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The current work investigates the capability of Large language models (LLMs) that are explicitly trained on large corpuses of medical knowledge (Med-PaLM 2) to predict psychiatric functioning from patient interviews and clinical…

Computation and Language · Computer Science 2023-08-04 Isaac R. Galatzer-Levy , Daniel McDuff , Vivek Natarajan , Alan Karthikesalingam , Matteo Malgaroli

Background: Advancements in large language models (LLMs) have opened new possibilities in psychiatric interviews, an underexplored area where LLMs could be valuable. This study focuses on enhancing psychiatric interviews by analyzing…

Artificial Intelligence · Computer Science 2025-02-11 Jae-hee So , Joonhwan Chang , Eunji Kim , Junho Na , JiYeon Choi , Jy-yong Sohn , Byung-Hoon Kim , Sang Hui Chu

As demand for mental health care outpaces clinician-delivered assessment, scalable screening tools are increasingly needed. Large language models (LLMs) may identify psychiatric risk from patient narratives, but their reliability across…

Computation and Language · Computer Science 2026-05-26 Jianfeng Zhu , Megan Korhummel , Ruoming Jin , Karin G. Coifman

Large language models (LLMs) are increasingly being used in a zero-shot fashion to assess mental health conditions, yet we have limited knowledge on what factors affect their accuracy. In this study, we utilize a clinical dataset of natural…

Patients with diabetes are at increased risk of comorbid depression or anxiety, complicating their management. This study evaluated the performance of large language models (LLMs) in detecting these symptoms from secure patient messages. We…

The advent of Large Language Models (LLMs) offers potential solutions to address problems such as shortage of medical resources and low diagnostic consistency in psychiatric clinical practice. Despite this potential, a robust and…

Computation and Language · Computer Science 2025-06-19 Shuyu Liu , Ruoxi Wang , Ling Zhang , Xuequan Zhu , Rui Yang , Xinzhu Zhou , Fei Wu , Zhi Yang , Cheng Jin , Gang Wang

Psychological support hotlines serve as critical lifelines for crisis intervention but encounter significant challenges due to rising demand and limited resources. Large language models (LLMs) offer potential support in crisis assessments,…

Computation and Language · Computer Science 2025-12-19 Guifeng Deng , Shuyin Rao , Tianyu Lin , Anlu Dai , Pan Wang , Junyi Xie , Haidong Song , Ke Zhao , Dongwu Xu , Zhengdong Cheng , Tao Li , Haiteng Jiang

NLP in mental health has been primarily social media focused. Real world practitioners also have high case loads and often domain specific variables, of which modern LLMs lack context. We take a dataset made by recruiting 644 participants,…

Computation and Language · Computer Science 2024-06-19 Ankit Aich , Avery Quynh , Pamela Osseyi , Amy Pinkham , Philip Harvey , Brenda Curtis , Colin Depp , Natalie Parde

Large Language Models (LLMs) have shown promise in various domains, including healthcare, with significant potential to transform mental health applications by enabling scalable and accessible solutions. This study aims to provide a…

Artificial Intelligence · Computer Science 2025-11-25 Abdelrahman Hanafi , Mohammed Saad , Noureldin Zahran , Radwa J. Hanafy , Mohammed E. Fouda

Large language models (LLMs) are increasingly attracting the attention of healthcare professionals for their potential to assist in diagnostic assessments, which could alleviate the strain on the healthcare system caused by a high patient…

Computation and Language · Computer Science 2025-01-03 Kaushik Roy , Harshul Surana , Darssan Eswaramoorthi , Yuxin Zi , Vedant Palit , Ritvik Garimella , Amit Sheth

We employ a Large Language Model (LLM) to convert unstructured psychological interviews into structured questionnaires spanning various psychiatric and personality domains. The LLM is prompted to answer these questionnaires by impersonating…

Computation and Language · Computer Science 2024-06-12 Gony Rosenman , Lior Wolf , Talma Hendler

Large language models (LLMs) have attracted significant attention for potential applications in digital health, while their application in mental health is subject to ongoing debate. This systematic review aims to evaluate the usage of LLMs…

Computers and Society · Computer Science 2024-08-14 Zhijun Guo , Alvina Lai , Johan Hilge Thygesen , Joseph Farrington , Thomas Keen , Kezhi Li

We investigate the use of Large Language Models (LLMs) for zero-shot prediction of Ryff Psychological Well-Being (PWB) scores from spontaneous speech. Using a few minutes of voice recordings from 111 participants in the PsyVoiD database, we…

Computation and Language · Computer Science 2026-05-13 Erfan Loweimi , Sofia de la Fuente Garcia , Saturnino Luz

The emergence of Small Language Models (SLMs) as privacy-preserving alternatives for sensitive applications raises a fundamental question about their inherent understanding capabilities compared to Large Language Models (LLMs). This paper…

Computation and Language · Computer Science 2025-07-15 Hong Jia , Shiya Fu , Feng Xia , Vassilis Kostakos , Ting Dang

Physicians considering clinical trials for their patients are met with the laborious process of checking many text based eligibility criteria. Large Language Models (LLMs) have shown to perform well for clinical information extraction and…

Machine Learning · Computer Science 2023-06-30 Danny M. den Hamer , Perry Schoor , Tobias B. Polak , Daniel Kapitan

Large language models (LLMs) have attracted growing interest as supportive tools for psychiatric assessment and clinical decision support. However, existing mental health benchmarks largely rely on social media data or supportive dialogue…

Computation and Language · Computer Science 2026-05-19 Hoyun Song , Migyeong Kang , Jisu Shin , Jihyun Kim , Chanbi Park , Hangyeol Yoo , Jihyun An , Alice Oh , Jinyoung Han , KyungTae Lim

Objectieve:This review aims to deliver a comprehensive analysis of Large Language Models (LLMs) utilization in mental health care, evaluating their effectiveness, identifying challenges, and exploring their potential for future application.…

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Large language models (LLMs) offer significant potential in enhancing psychiatric practice, from improving diagnostic accuracy to streamlining clinical documentation and therapeutic support. However, existing evaluation resources heavily…

Computation and Language · Computer Science 2025-11-25 Aya E. Fouda , Abdelrahamn A. Hassan , Radwa J. Hanafy , Mohammed E. Fouda

Disorganized thinking is a key diagnostic indicator of schizophrenia-spectrum disorders. Recently, clinical estimates of the severity of disorganized thinking have been shown to correlate with measures of how difficult speech transcripts…

Computation and Language · Computer Science 2025-03-27 Changye Li , Weizhe Xu , Serguei Pakhomov , Ellen Bradley , Dror Ben-Zeev , Trevor Cohen
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