Related papers: MIMOSA: Multi-parametric Imaging using Multiple-ec…
Molecule optimization is a fundamental task for accelerating drug discovery, with the goal of generating new valid molecules that maximize multiple drug properties while maintaining similarity to the input molecule. Existing generative…
Purpose: To develop a method for rapid sub-millimeter T1, T2, T2* and QSM mapping in a single scan using multi-contrast Learned Acquisition and Reconstruction Optimization (mcLARO). Methods: A pulse sequence was developed by interleaving…
Purpose: To develop and validate a multi-parametric SAturation-recovery single-SHot Acquisition (mSASHA) cardiac T1 and T2 mapping technique with high accuracy and precision in a single breath-hold. Methods: The mSASHA acquisition consists…
Purpose: Volumetric, high-resolution, quantitative mapping of brain tissue relaxation properties is hindered by long acquisition times and signal-to-noise (SNR) challenges. This study, for the first time, combines the time-efficient…
Purpose: To develop and evaluate methods for 1) reconstructing 3D-quantification using an interleaved Look-Locker acquisition sequence with T2 preparation pulse (3D-QALAS) time-series images using a low-rank subspace method, which enables…
Purpose: This study aims to develop a high-resolution whole-brain multi-parametric quantitative MRI approach for simultaneous mapping of myelin-water fraction (MWF), T1, T2, and proton-density (PD), all within a clinically feasible scan…
Purpose: To develop and evaluate a method for rapid estimation of multiparametric T1, T2, proton density (PD), and inversion efficiency (IE) maps from 3D-quantification using an interleaved Look-Locker acquisition sequence with T2…
Purpose: To improve the accuracy of multiparametric estimation, including myelin water fraction (MWF) quantification, and reduce scan time in 3D-QALAS by optimizing sequence parameters, using a self-supervised multilayer perceptron network.…
Purpose: T2* quantification from gradient echo magnetic resonance imaging is particularly affected by subject motion due to the high sensitivity to magnetic field inhomogeneities, which are influenced by motion and might cause signal loss.…
The 3D fast silent multi-parametric mapping sequence with zero echo time (MuPa-ZTE) is a novel quantitative MRI (qMRI) acquisition that enables nearly silent scanning by using a 3D phyllotaxis sampling scheme. MuPa-ZTE improves patient…
Novel methods for quantitative, transient-state multiparametric imaging are increasingly being demonstrated for assessment of disease and treatment efficacy. Here, we build on these by assessing the most common Non-Cartesian readout…
To realize Quantitative MRI (QMRI) with clinically acceptable scan time, acceleration factors achieved by conventional parallel imaging techniques are often inadequate. Further acceleration is possible using model-based reconstruction. We…
We propose PHIMO, a physics-informed learning-based motion correction method tailored to quantitative MRI. PHIMO leverages information from the signal evolution to exclude motion-corrupted k-space lines from a data-consistent…
Background: High-resolution MRI is critical for diagnosis, but long acquisition times limit clinical use. Super-resolution (SR) can enhance resolution post-scan, yet existing deep learning methods face fidelity-efficiency trade-offs.…
Quantitative magnetic resonance imaging might provide a more specific insight into disease process, progression and therapeutic response of multiple sclerosis. We present an extension of a previously published approach for the simultaneous…
Quantitative susceptibility mapping (QSM) involves acquisition and reconstruction of a series of images at multi-echo time points to estimate tissue field, which prolongs scan time and requires specific reconstruction technique. In this…
Quantification of tissue parameters using MRI is emerging as a powerful tool in clinical diagnosis and research studies. The need for multiple long scans with different acquisition parameters prohibits quantitative MRI from reaching…
This work addresses the problem of estimating proton density and T1 maps from two partially sampled K-space scans such that the total acquisition time remains approximately the same as a single scan. Existing multi parametric non linear…
We propose a dictionary-matching-free pipeline for multi-parametric quantitative MRI image computing. Our approach has two stages based on compressed sensing reconstruction and deep learned quantitative inference. The reconstruction phase…
Magnetic resonance imaging (MRI) is a cornerstone of clinical neuroimaging, yet conventional MRIs provide qualitative information heavily dependent on scanner hardware and acquisition settings. While quantitative MRI (qMRI) offers intrinsic…