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Diffusion models achieve state-of-the-art generative performance but suffer from high computational costs during inference due to the repeated evaluation of a heavy neural network. In this work, we propose Dual-Rate Diffusion, a method to…

Machine Learning · Computer Science 2026-05-19 Grigory Bartosh , David Ruhe , Emiel Hoogeboom , Jonathan Heek , Thomas Mensink , Tim Salimans

Score-based generative models (SGMs) have recently emerged as a promising class of generative models. However, a fundamental limitation is that their inference is very slow due to a need for many (e.g., 2000) iterations of sequential…

Computer Vision and Pattern Recognition · Computer Science 2022-12-06 Hengyuan Ma , Li Zhang , Xiatian Zhu , Jianfeng Feng

Low-dose CT (LDCT) imaging attracted a considerable interest for the reduction of the object's exposure to X-ray radiation. In recent years, supervised deep learning (DL) has been extensively studied for LDCT image reconstruction, which…

Image and Video Processing · Electrical Eng. & Systems 2022-10-06 Qiaoqiao Ding , Hui Ji , Yuhui Quan , Xiaoqun Zhang

While contrast-enhanced CT (CECT) is standard for assessing abdominal aortic aneurysms (AAA), the required iodinated contrast agents pose significant risks, including nephrotoxicity, patient allergies, and environmental harm. To reduce…

Computer Vision and Pattern Recognition · Computer Science 2025-12-08 Yuxuan Ou , Ning Bi , Jiazhen Pan , Jiancheng Yang , Boliang Yu , Usama Zidan , Regent Lee , Vicente Grau

Low-dose CT (LDCT) imaging is desirable in many clinical applications to reduce X-ray radiation dose to patients. Inspired by deep learning (DL), a recent promising direction of model-based iterative reconstruction (MBIR) methods for LDCT…

Image and Video Processing · Electrical Eng. & Systems 2021-02-18 Qiaoqiao Ding , Yuesong Nan , Hao Gao , Hui Ji

Diffusion magnetic resonance imaging datasets suffer from low Signal-to-Noise Ratio, especially at high b-values. Acquiring data at high b-values contains relevant information and is now of great interest for microstructural and…

Computer Vision and Pattern Recognition · Computer Science 2016-06-27 Samuel St-Jean , Pierrick Coupé , Maxime Descoteaux

Efficiently characterizing quantum dot (QD) devices is a critical bottleneck when scaling quantum processors based on confined spins. Measuring high-resolution charge stability diagrams (or CSDs, data maps which crucially define the…

Accurate quantification in positron emission tomography (PET) is essential for accurate diagnostic results and effective treatment tracking. A major issue encountered in PET imaging is attenuation. Attenuation refers to the diminution of…

A major challenge in X-ray computed tomography (CT) is reducing radiation dose while maintaining high quality of reconstructed images. To reduce the radiation dose, one can reduce the number of projection views (sparse-view CT); however, it…

Machine Learning · Statistics 2019-09-17 Xuehang Zheng , Il Yong Chun , Zhipeng Li , Yong Long , Jeffrey A. Fessler

Guided diffusion is a technique for conditioning the output of a diffusion model at sampling time without retraining the network for each specific task. One drawback of diffusion models, however, is their slow sampling process. Recent…

Computer Vision and Pattern Recognition · Computer Science 2023-01-30 Suttisak Wizadwongsa , Supasorn Suwajanakorn

Background: Daily or weekly cone-beam computed tomography (CBCT) scans are commonly used for accurate patient positioning during the image-guided radiotherapy (IGRT) process, making it an ideal option for adaptive radiotherapy (ART)…

Objective: Positron Emission Tomography (PET) has been a commonly used imaging modality in broad clinical applications. One of the most important tradeoffs in PET imaging is between image quality and radiation dose: high image quality comes…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Shaoyan Pan , Elham Abouei , Junbo Peng , Joshua Qian , Jacob F Wynne , Tonghe Wang , Chih-Wei Chang , Justin Roper , Jonathon A Nye , Hui Mao , Xiaofeng Yang

Diffusion models have found valuable applications in anomaly detection by capturing the nominal data distribution and identifying anomalies via reconstruction. Despite their merits, they struggle to localize anomalies of varying scales,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-25 Justin Tebbe , Jawad Tayyub

While diffusion-based image restoration (IR) methods have achieved remarkable success, they are still limited by the low inference speed attributed to the necessity of executing hundreds or even thousands of sampling steps. Existing…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Zongsheng Yue , Jianyi Wang , Chen Change Loy

Computed tomography is a widely used imaging modality with applications ranging from medical imaging to material analysis. One major challenge arises from the lack of scanning information at certain angles, resulting in distortion or…

The application of iodinated contrast media (ICM) improves the sensitivity and specificity of computed tomography (CT) for a wide range of clinical indications. However, overdose of ICM can cause problems such as kidney damage and…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Genyuan Zhang , Zihao Wang , Zhifan Gao , Lei Xu , Zhen Zhou , Haijun Yu , Jianjia Zhang , Xiujian Liu , Weiwei Zhang , Shaoyu Wang , Huazhu Fu , Fenglin Liu , Weiwen Wu

Denoising diffusion models have emerged as the go-to generative framework for solving inverse problems in imaging. A critical concern regarding these models is their performance on out-of-distribution tasks, which remains an under-explored…

Computer Vision and Pattern Recognition · Computer Science 2025-01-29 Riccardo Barbano , Alexander Denker , Hyungjin Chung , Tae Hoon Roh , Simon Arridge , Peter Maass , Bangti Jin , Jong Chul Ye

Inverse problems arise in a multitude of applications, where the goal is to recover a clean signal from noisy and possibly (non)linear observations. The difficulty of a reconstruction problem depends on multiple factors, such as the ground…

Image and Video Processing · Electrical Eng. & Systems 2024-08-21 Zalan Fabian , Berk Tinaz , Mahdi Soltanolkotabi

Diffusion models excel at image restoration via probabilistic modeling of forward noise addition and reverse denoising, and their ability to handle complex noise while preserving fine details makes them well-suited for Low-Light Image…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Ying Liu , Junchao Zhang , Caiyun Wu

Computed Tomography (CT) is widely used in healthcare for detailed imaging. However, Low-dose CT, despite reducing radiation exposure, often results in images with compromised quality due to increased noise. Traditional methods, including…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Herman Verinaz-Jadan , Su Yan