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Low-dose Computed Tomography (LDCT) reconstruction is an important task in medical image analysis. Recent years have seen many deep learning based methods, proved to be effective in this area. However, these methods mostly follow a…

Image and Video Processing · Electrical Eng. & Systems 2023-02-08 Runyi Li

Low-dose computed tomography (LDCT) is an important topic in the field of radiology over the past decades. LDCT reduces ionizing radiation-induced patient health risks but it also results in a low signal-to-noise ratio (SNR) and a potential…

Image and Video Processing · Electrical Eng. & Systems 2022-10-03 Wenjun Xia , Qing Lyu , Ge Wang

Low-dose computed tomography (LDCT) reduces radiation exposure but suffers from image artifacts and loss of detail due to quantum and electronic noise, potentially impacting diagnostic accuracy. Transformer combined with diffusion models…

Image and Video Processing · Electrical Eng. & Systems 2025-07-01 Qiqing Liu , Guoquan Wei , Zekun Zhou , Yiyang Wen , Liu Shi , Qiegen Liu

The generalization of deep learning-based low-dose computed tomography (CT) reconstruction models to doses unseen in the training data is important and remains challenging. Previous efforts heavily rely on paired data to improve the…

Image and Video Processing · Electrical Eng. & Systems 2025-06-30 Qi Gao , Zhihao Chen , Dong Zeng , Junping Zhang , Jianhua Ma , Hongming Shan

Low-dose computed tomography (LDCT) reduces patient radiation exposure but introduces substantial noise that degrades image quality and hinders diagnostic accuracy. Existing denoising approaches often require many diffusion steps, limiting…

Medical Physics · Physics 2025-10-29 Qiang Li , Mojtaba Safari , Shansong Wang , Huiqiao Xie , Jie Ding , Tonghe Wang , Xiaofeng Yang

Low-dose computed tomography (CT) images suffer from noise and artifacts due to photon starvation and electronic noise. Recently, some works have attempted to use diffusion models to address the over-smoothness and training instability…

Image and Video Processing · Electrical Eng. & Systems 2024-01-10 Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Hongming Shan

Score-based diffusion models have significantly advanced generative deep learning for image processing. Measurement conditioned models have also been applied to inverse problems such as CT reconstruction. However, the conventional approach,…

Medical Physics · Physics 2025-02-24 Matthew Tivnan , Dufan Wu , Quanzheng Li

While diffusion models have set a new benchmark for quality in Low-Dose Computed Tomography (LDCT) denoising, their clinical adoption is critically hindered by extreme computational costs, with inference times often exceeding thousands of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-30 Tangtangfang Fang , Jingxi Hu , Xiangjian He , Jiaqi Yang

Limited-Angle Computed Tomography (LACT) is a challenging inverse problem where missing angular projections lead to incomplete sinograms and severe artifacts in the reconstructed images. While recent learning-based methods have demonstrated…

Image and Video Processing · Electrical Eng. & Systems 2025-07-09 Jiaqi Guo , Santiago López-Tapia

Computed tomography (CT) involves a patient's exposure to ionizing radiation. To reduce the radiation dose, we can either lower the X-ray photon count or down-sample projection views. However, either of the ways often compromises image…

Image and Video Processing · Electrical Eng. & Systems 2023-10-12 Wenjun Xia , Yongyi Shi , Chuang Niu , Wenxiang Cong , Ge Wang

Dose reduction in computed tomography (CT) is essential for decreasing radiation risk in clinical applications. Iterative reconstruction is one of the most promising ways to compensate for the increased noise due to reduction of photon…

Image and Video Processing · Electrical Eng. & Systems 2021-03-24 Zhuonan He , Yikun Zhang , Yu Guan , Shanzhou Niu , Yi Zhang , Yang Chen , Qiegen Liu

Diffusion models have significant impact on wide range of generative tasks, especially on image inpainting and restoration. Although the improvements on aiming for decreasing number of function evaluations (NFE), the iterative results are…

Image and Video Processing · Electrical Eng. & Systems 2024-11-20 Mahmut S. Gokmen , Jie Zhang , Ge Wang , Jin Chen , Cody Bumgardner

Low-dose computed tomography (CT) denoising is crucial for reduced radiation exposure while ensuring diagnostically acceptable image quality. Despite significant advancements driven by deep learning (DL) in recent years, existing DL-based…

Computer Vision and Pattern Recognition · Computer Science 2025-08-26 Zhihao Chen , Qi Gao , Zilong Li , Junping Zhang , Yi Zhang , Jun Zhao , Hongming Shan

Positron Emission Tomography (PET) is an important clinical imaging tool but inevitably introduces radiation hazards to patients and healthcare providers. Reducing the tracer injection dose and eliminating the CT acquisition for attenuation…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Tianqi Chen , Jun Hou , Yinchi Zhou , Huidong Xie , Xiongchao Chen , Qiong Liu , Xueqi Guo , Menghua Xia , James S. Duncan , Chi Liu , Bo Zhou

Low-Dose computer tomography (LDCT) is an ideal alternative to reduce radiation risk in clinical applications. Although supervised-deep-learning-based reconstruction methods have demonstrated superior performance compared to conventional…

Image and Video Processing · Electrical Eng. & Systems 2024-05-24 Feng Wang , Renfang Wang , Hong Qiu

Reducing scan times, radiation dose, and enhancing image quality for lower-performance scanners, are critical in low-dose PET imaging. Deep learning techniques have been investigated for PET image denoising. However, existing models have…

Limited-Angle Computed Tomography (LACT) is a non-destructive evaluation technique used in a variety of applications ranging from security to medicine. The limited angle coverage in LACT is often a dominant source of severe artifacts in the…

Image and Video Processing · Electrical Eng. & Systems 2022-11-23 Jiaming Liu , Rushil Anirudh , Jayaraman J. Thiagarajan , Stewart He , K. Aditya Mohan , Ulugbek S. Kamilov , Hyojin Kim

Diffusion models have been demonstrated as powerful deep learning tools for image generation in CT reconstruction and restoration. Recently, diffusion posterior sampling, where a score-based diffusion prior is combined with a likelihood…

Medical Physics · Physics 2024-09-02 Shudong Li , Xiao Jiang , Matthew Tivnan , Grace J. Gang , Yuan Shen , J. Webster Stayman

Objective: Cone-beam computed tomography (CBCT) provides a low-dose imaging alternative to conventional CT, but suffers from noise, scatter, and artifacts that degrade image quality. Synthetic CT (sCT) aims to translate CBCT to high-quality…

Medical Physics · Physics 2025-09-23 Alzahra Altalib , Chunhui Li , Alessandro Perelli

As PET imaging is accompanied by substantial radiation exposure and cancer risk, reducing radiation dose in PET scans is an important topic. Recently, diffusion models have emerged as the new state-of-the-art generative model to generate…

Image and Video Processing · Electrical Eng. & Systems 2023-11-30 Huidong Xie , Weijie Gan , Bo Zhou , Xiongchao Chen , Qiong Liu , Xueqi Guo , Liang Guo , Hongyu An , Ulugbek S. Kamilov , Ge Wang , Chi Liu
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