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While machine learning (ML) models have been able to achieve unprecedented accuracies across various prediction tasks in quantum chemistry, it is now apparent that accuracy on a test set alone is not a guarantee for robust chemical modeling…

Single-model ensembles (SMEs) have attracted attention as a way to approximate some of the benefits of deep ensembles within a single network. However, under an approximately matched parameter budget, it remains unclear whether model…

Machine Learning · Computer Science 2026-05-13 Tatsuhito Hasegawa , Taisei Tanaka

Many important physical processes have dynamics that are too complex to completely model analytically. Optimisation of such processes often relies on intuition, trial-and-error, or the construction of empirical models. Machine learning…

Estimated uncertainty by approximate posteriors in Bayesian neural networks are prone to miscalibration, which leads to overconfident predictions in critical tasks that have a clear asymmetric cost or significant losses. Here, we extend the…

Machine Learning · Computer Science 2022-06-17 Biraja Ghoshal , Allan Tucker

Shallow ensembles provide a convenient strategy for uncertainty quantification in machine learning interatomic potentials, that is computationally efficient because the different ensemble members share a large part of the model weights. In…

Chemical Physics · Physics 2026-02-18 Moritz Schäfer , Matthias Kellner , Johannes Kästner , Michele Ceriotti

Due to the computational complexity of evaluating interatomic forces from first principles, the creation of interatomic machine learning force fields has become a highly active field of research. However, the generation of training datasets…

Machine Learning · Computer Science 2025-07-21 Tim Rensmeyer , Denis Kramer , Oliver Niggemann

Multimodal semantic understanding often has to deal with uncertainty, which means the obtained messages tend to refer to multiple targets. Such uncertainty is problematic for our interpretation, including inter- and intra-modal uncertainty.…

Computer Vision and Pattern Recognition · Computer Science 2023-07-21 Yatai Ji , Junjie Wang , Yuan Gong , Lin Zhang , Yanru Zhu , Hongfa Wang , Jiaxing Zhang , Tetsuya Sakai , Yujiu Yang

Uncertainty estimation in machine learning is paramount for enhancing the reliability and interpretability of predictive models, especially in high-stakes real-world scenarios. Despite the availability of numerous methods, they often pose a…

Computer Vision and Pattern Recognition · Computer Science 2023-08-16 Anton Baumann , Thomas Roßberg , Michael Schmitt

Predictions of uncertainty-aware models are diverse, ranging from single point estimates (often averaged over prediction samples) to predictive distributions, to set-valued or credal-set representations. We propose a novel unified…

Machine Learning · Computer Science 2025-02-18 Shireen Kudukkil Manchingal , Muhammad Mubashar , Kaizheng Wang , Fabio Cuzzolin

Machine learned force fields typically require manual construction of training sets consisting of thousands of first principles calculations, which can result in low training efficiency and unpredictable errors when applied to structures…

Computational Physics · Physics 2019-11-21 Jonathan Vandermause , Steven B. Torrisi , Simon Batzner , Yu Xie , Lixin Sun , Alexie M. Kolpak , Boris Kozinsky

Decision Focused Learning has emerged as a critical paradigm for integrating machine learning with downstream optimisation. Despite its promise, existing methodologies predominantly rely on probabilistic models and focus narrowly on task…

Machine Learning · Computer Science 2025-03-21 Keivan Shariatmadar , Neil Yorke-Smith , Ahmad Osman , Fabio Cuzzolin , Hans Hallez , David Moens

Uranium mononitride (UN) is a promising accident-tolerant fuel because of its high fissile density and high thermal conductivity. In this study, we developed the first machine learning interatomic potentials for reliable atomic-scale…

This paper introduces an active learning approach to the fitting of machine learning interatomic potentials. Our approach is based on the D-optimality criterion for selecting atomic configurations on which the potential is fitted. It is…

Computational Physics · Physics 2017-09-19 Evgeny V. Podryabinkin , Alexander V. Shapeev

This paper presents a deep learning based model predictive control (MPC) algorithm for systems with unmatched and bounded state-action dependent uncertainties of unknown structure. We utilize a deep neural network (DNN) as an oracle in the…

Machine Learning · Computer Science 2023-04-25 Mateus V. Gasparino , Prabhat K. Mishra , Girish Chowdhary

Machine Learning-assisted directed evolution (MLDE) is a powerful tool for efficiently navigating antibody fitness landscapes. Many structure-aware MLDE pipelines rely on a single conformation or a single committee across all conformations,…

Machine Learning · Computer Science 2025-12-03 Mia Adler , Carrie Liang , Brian Peng , Oleg Presnyakov , Justin M. Baker , Jannelle Lauffer , Himani Sharma , Barry Merriman

Multi-agent systems are increasingly equipped with heterogeneous multimodal sensors, enabling richer perception but introducing modality-specific and agent-dependent uncertainty. Existing multi-agent collaboration frameworks typically…

Machine Learning · Computer Science 2026-02-05 Rui Liu , Pratap Tokekar , Ming Lin

In this work, we propose a method for efficient learning of a multi-dimensional function. This method combines the Bayesian neural networks and the query-by-committee method. A committee made of deep Bayesian neural networks not only can…

Computational Physics · Physics 2020-11-13 Li Chen , Xiao Liang , Hui Zhai

Recent advances in machine-learning interatomic potentials have enabled the efficient modeling of complex atomistic systems with an accuracy that is comparable to that of conventional quantum mechanics based methods. At the same time, the…

Materials Science · Physics 2021-05-06 April M. Miksch , Tobias Morawietz , Johannes Kästner , Alexander Urban , Nongnuch Artrith

The length and time scales of atomistic simulations are limited by the computational cost of the methods used to predict material properties. In recent years there has been great progress in the use of machine learning algorithms to develop…

Computational Physics · Physics 2022-11-03 Alberto Hernandez , Adarsh Balasubramanian , Fenglin Yuan , Simon Mason , Tim Mueller

Universal machine learning interatomic potentials (uMLIPs) are reshaping atomistic simulation as foundation models, delivering near \textit{ab initio} accuracy at a fraction of the cost. Yet the lack of reliable, general uncertainty…

Materials Science · Physics 2025-07-30 Kai Liu , Zixiong Wei , Wei Gao , Poulumi Dey , Marcel H. F. Sluiter , Fei Shuang