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Respiratory diseases remain major global health challenges, and traditional auscultation is often limited by subjectivity, environmental noise, and inter-clinician variability. This study presents an explainable multimodal deep learning…

Sound · Computer Science 2025-12-02 S M Asiful Islam Saky , Md Rashidul Islam , Md Saiful Arefin , Shahaba Alam

Importance: We introduce a novel Retrieval Augmented Generation (RAG)-Large Language Model (LLM) framework as a Clinical Decision Support Systems (CDSS) to support safe medication prescription. Objective: To evaluate the efficacy of…

The recent mass adoption of DNNs, even in safety-critical scenarios, has shifted the focus of the research community towards the creation of inherently intrepretable models. Concept Bottleneck Models (CBMs) constitute a popular approach…

Machine Learning · Computer Science 2023-08-22 Konstantinos P. Panousis , Dino Ienco , Diego Marcos

Concept Bottleneck Models (CBMs) aim to deliver interpretable predictions by routing decisions through a human-understandable concept layer, yet they often suffer reduced accuracy and concept leakage that undermines faithfulness. We…

Machine Learning · Computer Science 2026-02-17 Karim Galliamov , Syed M Ahsan Kazmi , Adil Khan , Adín Ramírez Rivera

Explainable AI seeks to bring light to the decision-making processes of black-box models. Traditional saliency-based methods, while highlighting influential data segments, often lack semantic understanding. Recent advancements, such as…

Artificial Intelligence · Computer Science 2023-10-12 Bo Pan , Zhenke Liu , Yifei Zhang , Liang Zhao

Machine learning accelerates molecular property prediction, yet state-of-the-art Large Language Models and Graph Neural Networks operate as black boxes. In drug discovery, where safety is critical, this opacity risks masking false…

Machine Learning · Computer Science 2026-03-03 Oscar Rivera , Ziqing Wang , Matthieu Dagommer , Abhishek Pandey , Kaize Ding

Early diagnosis of Alzheimer's Disease (AD) faces multiple data-related challenges, including high variability in patient data, limited access to specialized diagnostic tests, and overreliance on single-type indicators. These challenges are…

Quantitative Methods · Quantitative Biology 2025-03-05 Yizong Xing , Dhita Putri Pratama , Yuke Wang , Yufan Zhang , Brian E. Chapman

Medical and public health experts must make real-time resource decisions, such as expanding hospital bed capacity, based on projected hospitalization trends during large-scale healthcare disruptions (e.g., operational failures or…

Artificial Intelligence · Computer Science 2026-04-28 Rhea Makkuni , Ananya Joshi

The biomedical field relies heavily on concept linking in various areas such as literature mining, graph alignment, information retrieval, question-answering, data, and knowledge integration. Although large language models (LLMs) have made…

Computation and Language · Computer Science 2023-07-04 Qinyong Wang , Zhenxiang Gao , Rong Xu

This paper explores the integration of Large Language Models (LLMs) into Automatic Speech Recognition (ASR) systems to improve transcription accuracy. The increasing sophistication of LLMs, with their in-context learning capabilities and…

Computation and Language · Computer Science 2025-06-03 Zeping Min , Jinbo Wang

Visual explanation methods have an important role in the prognosis of the patients where the annotated data is limited or unavailable. There have been several attempts to use gradient-based attribution methods to localize pathology from…

Image and Video Processing · Electrical Eng. & Systems 2021-06-24 Ugur Demir , Ismail Irmakci , Elif Keles , Ahmet Topcu , Ziyue Xu , Concetto Spampinato , Sachin Jambawalikar , Evrim Turkbey , Baris Turkbey , Ulas Bagci

Concept Bottleneck Models (CBMs) offer inherent interpretability by initially translating images into human-comprehensible concepts, followed by a linear combination of these concepts for classification. However, the annotation of concepts…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Hangzhou He , Lei Zhu , Xinliang Zhang , Shuang Zeng , Qian Chen , Yanye Lu

Concept bottleneck models are interpretable predictive models that are often used in domains where model trust is a key priority, such as healthcare. They identify a small number of human-interpretable concepts in the data, which they then…

Machine Learning · Computer Science 2024-12-25 Katrina Brown , Marton Havasi , Finale Doshi-Velez

The shortage of clinical workforce presents significant challenges in mental healthcare, limiting access to formal diagnostics and services. We aim to tackle this shortage by integrating a customized large language model (LLM) into the…

Computation and Language · Computer Science 2025-05-02 Sichang Tu , Abigail Powers , Natalie Merrill , Negar Fani , Sierra Carter , Stephen Doogan , Jinho D. Choi

Concept Bottleneck Models (CBMs) introduce interpretability to black-box deep learning models by predicting labels through human-understandable concepts. However, unlike humans, who identify objects at different levels of abstraction using…

Computer Vision and Pattern Recognition · Computer Science 2026-04-06 Haodong Xie , Yujun Cai , Rahul Singh Maharjan , Yiwei Wang , Federico Tavella , Angelo Cangelosi

Concept Bottleneck Models (CBMs) use a set of human-interpretable concepts to predict the final task label, enabling domain experts to not only validate the CBM's predictions, but also intervene on incorrect concepts at test time. However,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Eric Enouen , Sainyam Galhotra

There is vivid research on adapting Large Language Models (LLMs) to perform a variety of tasks in high-stakes domains such as healthcare. Despite their popularity, there is a lack of understanding of the extent and contributing factors that…

Computation and Language · Computer Science 2024-06-07 Anand Subramanian , Viktor Schlegel , Abhinav Ramesh Kashyap , Thanh-Tung Nguyen , Vijay Prakash Dwivedi , Stefan Winkler

This paper describes a multi-modal approach for the automatic detection of Alzheimer's disease proposed in the context of the INESC-ID Human Language Technology Laboratory participation in the ADReSS 2020 challenge. Our classification…

Audio and Speech Processing · Electrical Eng. & Systems 2020-06-01 Anna Pompili , Thomas Rolland , Alberto Abad

The exponential growth of data and advancements in big data technologies have created a demand for more efficient and automated approaches to data analysis and storytelling. However, automated data analysis systems still face challenges in…

Computation and Language · Computer Science 2025-01-03 Chengze Zhang , Changshan Li , Shiyang Gao

This study addresses the critical need for enhanced situational awareness in autonomous driving (AD) by leveraging the contextual reasoning capabilities of large language models (LLMs). Unlike traditional perception systems that rely on…

Artificial Intelligence · Computer Science 2025-01-09 Xuewen Luo , Fan Ding , Fengze Yang , Yang Zhou , Junnyong Loo , Hwa Hui Tew , Chenxi Liu