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A common way of studying the relationship between neural activity and behavior is through the analysis of neuronal spike trains that are recorded using one or more electrodes implanted in the brain. Each spike train typically contains…

Applications · Statistics 2011-04-15 Mengxin Li , Wei-Liem Loh

The mammalian hippocampus plays a principal role in producing a cognitive map of space---an internalized representation of the animal's environment. The neuronal mechanisms producing this map depend primarily on the temporal structure of…

Neurons and Cognition · Quantitative Biology 2016-03-22 Edward Basso , Mamiko Arai , Yuri Dabaghian

Identification of patterns from discrete data time-series for statistical inference, threat detection, social opinion dynamics, brain activity prediction has received recent momentum. In addition to the huge data size, the associated…

Machine Learning · Computer Science 2019-02-22 Ruochen Yang , Gaurav Gupta , Paul Bogdan

There is extensive evidence that biological neural networks encode information in the precise timing of the spikes generated and transmitted by neurons, which offers several advantages over rate-based codes. Here we adopt a vector space…

Neurons and Cognition · Quantitative Biology 2019-07-16 Dorian Florescu , Daniel Coca

In recent years, new technologies in neuroscience have made it possible to measure the activities of large numbers of neurons simultaneously in behaving animals. For each neuron, a fluorescence trace is measured; this can be seen as a…

Applications · Statistics 2017-11-15 Sean Jewell , Daniela Witten

The brain exhibits capabilities of fast incremental learning from few noisy examples, as well as the ability to associate similar memories in autonomously-created categories and to combine contextual hints with sensory perceptions. Together…

In the brain, both neurons and glial cells work in conjunction with each other during information processing. Stimulation of neurons can cause calcium oscillations in astrocytes which in turn can affect neuronal calcium dynamics. The…

Neurons and Cognition · Quantitative Biology 2023-08-16 Bhanu Sharma , Spandan Kumar , Subhendu Ghosh , Vikram Singh

The precise timing of spikes emitted by neurons plays a crucial role in shaping the response of efferent biological neurons. This temporal dimension of neural activity holds significant importance in understanding information processing in…

Neurons and Cognition · Quantitative Biology 2023-07-27 Antoine Grimaldi , Laurent U Perrinet

Now over 20 years old, functional MRI (fMRI) has a large and growing literature that is best synthesised with meta-analytic tools. As most authors do not share image data, only the peak activation coordinates (foci) reported in the paper…

Multi-electrode arrays covering several square millimeters of neural tissue provide simultaneous access to population signals such as extracellular potentials and spiking activity of one hundred or more individual neurons. The…

Neurons and Cognition · Quantitative Biology 2024-11-11 Johanna Senk , Espen Hagen , Sacha J. van Albada , Markus Diesmann

Bayesian inference provides a principled framework for understanding brain function, while neural activity in the brain is inherently spike-based. This paper bridges these two perspectives by designing spiking neural networks that simulate…

Neurons and Cognition · Quantitative Biology 2026-01-01 Sepideh Adamiat , Wouter M. Kouw , Bert de Vries

In cognition, response times and choices in decision-making tasks are commonly modeled using Drift Diffusion Models (DDMs), which describe the accumulation of evidence for a decision as a stochastic process, specifically a Brownian motion,…

Machine Learning · Computer Science 2025-06-12 Sophie Jaffard , Giulia Mezzadri , Patricia Reynaud-Bouret , Etienne Tanré

In this paper, we focus on identifying differentially activated brain regions using a light sheet fluorescence microscopy - a recently developed technique for whole-brain imaging. Most existing statistical methods solve this problem by…

Brain activity following stimulus presentation and during resting state are often the result of highly coordinated responses of large numbers of neurons both locally and globally. Coordinated activity of neurons can give rise to…

Applications · Statistics 2015-07-20 Carolina Euan , Hernando Ombao , Joaquin Ortega

While traditional feed-forward filter models can reproduce the rate responses of retinal ganglion neurons to simple stimuli, they cannot explain why synchrony between spikes is much higher than expected by Poisson firing [6], and can be…

Neurons and Cognition · Quantitative Biology 2020-05-07 Christopher Warner , Friedrich T. Sommer

A goal of low-level neural processes is to build an efficient code extracting the relevant information from the sensory input. It is believed that this is implemented in cortical areas by elementary inferential computations dynamically…

Neurons and Cognition · Quantitative Biology 2007-05-23 Laurent Perrinet

The detection of neuronal communities is addressed with basis on two important concepts from neuroscience: facilitation of neuronal firing and nearly simultaneous beginning of activation of sets of neurons. More specifically,…

Physics and Society · Physics 2008-01-29 Luciano da Fontoura Costa

Oscillations of free intracellular calcium concentration are thought to be important in the control of a wide variety of physiological phenomena, and there is long-standing interest in understanding these oscillations via the investigation…

Dynamical Systems · Mathematics 2024-01-31 Behnaz Rahmani , Samuel Jelbart , Vivien Kirk , James Sneyd

Biological neurons and their in-silico emulations for neuromorphic artificial intelligence (AI) use extraordinarily energy-efficient mechanisms, such as spike-based communication and local synaptic plasticity. It remains unclear whether…

Neural and Evolutionary Computing · Computer Science 2021-06-17 Timoleon Moraitis , Abu Sebastian , Evangelos Eleftheriou

A common analytical problem in neuroscience is the interpretation of neural activity with respect to sensory input or behavioral output. This is typically achieved by regressing measured neural activity against known stimuli or behavioral…

Computation · Statistics 2016-06-28 Kamiar Rahnama Rad , Timothy A. Machado , Liam Paninski
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