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Protein language models (PLMs) have demonstrated remarkable success in protein modeling and design, yet their internal mechanisms for predicting structure and function remain poorly understood. Here we present a systematic approach to…

Biomolecules · Quantitative Biology 2024-12-18 Elana Simon , James Zou

Sparse autoencoders (SAEs) are a popular method for decomposing Large Langage Models (LLM) activations into interpretable latents. However, due to their substantial training cost, most academic research uses open-source SAEs which are only…

Machine Learning · Computer Science 2025-06-13 Patrick Leask , Neel Nanda , Noura Al Moubayed

Sparse Autoencoders (SAEs) are widely employed for mechanistic interpretability and model steering. Within this context, steering is by design performed by means of decoding altered SAE intermediate representations. This procedure…

Machine Learning · Computer Science 2025-12-08 Antonio Bărbălau , Cristian Daniel Păduraru , Teodor Poncu , Alexandru Tifrea , Elena Burceanu

Sparse autoencoders (SAEs) are a technique for sparse decomposition of neural network activations into human-interpretable features. However, current SAEs suffer from feature absorption, where specialized features capture instances of…

Machine Learning · Computer Science 2025-09-29 Anton Korznikov , Andrey Galichin , Alexey Dontsov , Oleg Rogov , Elena Tutubalina , Ivan Oseledets

LLMs increasingly require surgical model editing to enhance domain-specific capabilities without incurring the computational cost or catastrophic forgetting associated with full fine-tuning. Sparse Autoencoders (SAEs) have emerged as a…

Machine Learning · Computer Science 2026-05-28 Li Lei , Madalina Ciobanu , Qingqing Mao , Ritankar Das

Sparse Autoencoder (SAE) features have become essential tools for mechanistic interpretability research. SAE features are typically characterized by examining their activating examples, which are often "monosemantic" and align with human…

Artificial Intelligence · Computer Science 2025-09-30 Claire Tian , Katherine Tian , Nathan Hu

Large Language Models (LLMs) offer extensive knowledge across various domains, but they may inadvertently memorize sensitive, unauthorized, or malicious data, such as personal information in the medical and financial sectors. Machine…

Computation and Language · Computer Science 2024-10-16 YuXuan Wu , Bonaventure F. P. Dossou , Dianbo Liu

Current sparse autoencoder (SAE) approaches to neural network interpretability assume that activations can be decomposed through linear superposition into sparse, interpretable features. Despite high reconstruction fidelity, SAEs…

Neurons and Cognition · Quantitative Biology 2025-12-10 Omar Claflin

Protein language models have revolutionized structure prediction, but their nonlinear nature obscures how sequence representations inform structure prediction. While sparse autoencoders (SAEs) offer a path to interpretability here by…

Biomolecules · Quantitative Biology 2025-03-13 Nithin Parsan , David J. Yang , John J. Yang

Sparse autoencoders (SAEs) are now standard tools for decomposing language model activations into interpretable features, and automated interpretability pipelines routinely assign each feature a short natural-language explanation. Existing…

Machine Learning · Computer Science 2026-05-14 Jordan F. McCann

A popular new method in mechanistic interpretability is to train high-dimensional sparse autoencoders (SAEs) on neuron activations and use SAE features as the atomic units of analysis. However, the body of evidence on whether SAE feature…

Machine Learning · Computer Science 2024-09-10 Maheep Chaudhary , Atticus Geiger

Unlearning methods for vision-language models (VLMs) have primarily adapted techniques from large language models (LLMs), relying on weight updates that demand extensive annotated forget sets. Moreover, these methods perform unlearning at a…

Computer Vision and Pattern Recognition · Computer Science 2025-03-21 Qing Li , Jiahui Geng , Derui Zhu , Fengyu Cai , Chenyang Lyu , Fakhri Karray

Sparse autoencoders (SAEs) promise a unified approach for mechanistic interpretability, concept discovery, and model steering in LLMs and LVLMs. However, realizing this potential requires learned features to be both interpretable and…

Machine Learning · Computer Science 2026-04-01 Akshay Kulkarni , Tsui-Wei Weng , Vivek Narayanaswamy , Shusen Liu , Wesam A. Sakla , Kowshik Thopalli

Learning hierarchical features in Sparse Autoencoders (SAEs) is essential for capturing the structured nature of real-world data and mitigating issues like feature absorption or splitting. Existing works attempt to identify hierarchical…

Machine Learning · Computer Science 2026-05-12 Tue M. Cao , Hoang X. Nhat , Raed Alharbi , Phi Le Nguyen , My T. Thai

Existing works are dedicated to untangling atomized numerical components (features) from the hidden states of Large Language Models (LLMs). However, they typically rely on autoencoders constrained by some training-time regularization on…

Machine Learning · Computer Science 2026-02-13 Hakaze Cho , Haolin Yang , Yanshu Li , Brian M. Kurkoski , Naoya Inoue

Sparse autoencoders (SAEs) have emerged as a promising approach for learning interpretable features from neural network activations. However, the optimization landscape for SAE training can be challenging due to correlations in the input…

Machine Learning · Computer Science 2025-11-19 Ashwin Saraswatula , David Klindt

Despite their strong performance, Dense Passage Retrieval (DPR) models suffer from a lack of interpretability. In this work, we propose a novel interpretability framework that leverages Sparse Autoencoders (SAEs) to decompose previously…

Information Retrieval · Computer Science 2025-08-28 Seongwan Park , Taeklim Kim , Youngjoong Ko

Sparse Autoencoders (SAEs) are widely used to steer large language models (LLMs), based on the assumption that their interpretable features naturally enable effective model behavior steering. Yet, a fundamental question remains unanswered:…

Machine Learning · Computer Science 2025-10-07 Xu Wang , Yan Hu , Benyou Wang , Difan Zou

We identify semantically coherent, context-consistent network components in large language models (LLMs) using coactivation of sparse autoencoder (SAE) features collected from just a handful of prompts. Focusing on concept-relation…

Computation and Language · Computer Science 2026-04-21 Ruixuan Deng , Xiaoyang Hu , Miles Gilberti , Shane Storks , Aman Taxali , Mike Angstadt , Chandra Sripada , Joyce Chai

Sparse Autoencoders (SAEs) have emerged as a predominant tool in mechanistic interpretability, aiming to identify interpretable monosemantic features. However, how does sparse encoding organize the representations of activation vector from…

Machine Learning · Computer Science 2025-05-29 Wenjie Sun , Bingzhe Wu , Zhile Yang , Chengke Wu