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Denoising diffusion models (DDMs) have recently attracted increasing attention by showing impressive synthesis quality. DDMs are built on a diffusion process that pushes data to the noise distribution and the models learn to denoise. In…

Machine Learning · Computer Science 2023-05-16 Jaemoo Choi , Yesom Park , Myungjoo Kang

Conditional medical image generation plays an important role in many clinically relevant imaging tasks. However, existing methods still face a fundamental challenge in balancing inference efficiency, patient-specific fidelity, and…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Zirong Li , Siyuan Mei , Weiwen Wu , Andreas Maier , Lina Gölz , Yan Xia

AI models for lung cancer screening are limited by data scarcity, impacting generalizability and clinical applicability. Generative models address this issue but are constrained by training data variability. We introduce SYN-LUNGS, a…

The reconstruction of X-rays CT images from sparse or limited-angle geometries is a highly challenging task. The lack of data typically results in artifacts in the reconstructed image and may even lead to object distortions. For this…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Davide Evangelista , Pasquale Cascarano , Elena Loli Piccolomini

Lung cancer is a severe menace to human health, due to which millions of people die because of late diagnoses of cancer; thus, it is vital to detect the disease as early as possible. The Computerized chest analysis Tomography of scan is…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Ahmed Saihood , Hossein Karshenas , AhmadReza Naghsh Nilchi

Deep learning is widely applied in computer-aided pathological diagnosis, which alleviates the pathologist workload and provide timely clinical analysis. However, most models generally require large-scale annotated data for training, which…

Computer Vision and Pattern Recognition · Computer Science 2024-03-12 Zeyu Liu , Tianyi Zhang , Yufang He , Yunlu Feng , Yu Zhao , Guanglei Zhang

Annual low dose computed tomography (CT) lung screening is currently advised for individuals at high risk of lung cancer (e.g., heavy smokers between 55 and 80 years old). The recommended screening practice significantly reduces all-cause…

Computer Vision and Pattern Recognition · Computer Science 2020-02-18 Riqiang Gao , Lingfeng Li , Yucheng Tang , Sanja L. Antic , Alexis B. Paulson , Yuankai Huo , Kim L. Sandler , Pierre P. Massion , Bennett A. Landman

Real-world data often has a long-tailed distribution, where the scarcity of tail samples significantly limits the model's generalization ability. Denoising Diffusion Probabilistic Models (DDPM) are generative models based on stochastic…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Jingyu Kong , Yuan Guo , Yu Wang , Yuping Duan

Denoising Diffusion Probabilistic Models (DDPMs) have garnered popularity for data generation across various domains. However, a significant bottleneck is the necessity for whole-network computation during every step of the generative…

Computer Vision and Pattern Recognition · Computer Science 2024-05-27 Shuai Yang , Yukang Chen , Luozhou Wang , Shu Liu , Yingcong Chen

Diffusion Probabilistic Models (DPMs) suffer from inefficient inference due to their slow sampling and high memory consumption, which limits their applicability to various medical imaging applications. In this work, we propose a novel…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Fahim Ahmed Zaman , Mathews Jacob , Amanda Chang , Kan Liu , Milan Sonka , Xiaodong Wu

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Artifact removal is critical for accurate analysis and interpretation of Electroencephalogram (EEG) signals. Traditional methods perform poorly with strong artifact-EEG correlations or single-channel data. Recent advances in diffusion-based…

Image and Video Processing · Electrical Eng. & Systems 2025-09-19 Feixue Shao , Xueyu Liu , Yongfei Wu , Jianbo Lu , Guiying Yan , Weihua Yang

Non-contrast CT (NCCT) imaging may reduce image contrast and anatomical visibility, potentially increasing diagnostic uncertainty. In contrast, contrast-enhanced CT (CECT) facilitates the observation of regions of interest (ROI). Leading…

Image and Video Processing · Electrical Eng. & Systems 2024-11-18 Tingyi Lin , Pengju Lyu , Jie Zhang , Yuqing Wang , Cheng Wang , Jianjun Zhu

Computational fluid dynamics (CFD) is a powerful tool for modeling turbulent flow and is commonly used for urban microclimate simulations. However, traditional CFD methods are computationally intensive, requiring substantial hardware…

One-shot medical image segmentation faces fundamental challenges in prototype representation due to limited annotated data and significant anatomical variability across patients. Traditional prototype-based methods rely on deterministic…

Computer Vision and Pattern Recognition · Computer Science 2025-12-23 Ziyuan Gao , Philippe Morel

Deep learning methods have impacted almost every research field, demonstrating notable successes in medical imaging tasks such as denoising and super-resolution. However, the prerequisite for deep learning is data at scale, but data sharing…

Medical Physics · Physics 2024-02-16 Yongyi Shi , Wenjun Xia , Chuang Niu , Christopher Wiedeman , Ge Wang

Generating diverse, all-atom conformational ensembles of dynamic proteins such as G-protein-coupled receptors (GPCRs) is critical for understanding their function, yet most generative models simplify atomic detail or ignore conformational…

Biomolecules · Quantitative Biology 2025-08-19 Aditya Sengar , Ali Hariri , Daniel Probst , Patrick Barth , Pierre Vandergheynst

Tumor synthesis enables the creation of artificial tumors in medical images, facilitating the training of AI models for tumor detection and segmentation. However, success in tumor synthesis hinges on creating visually realistic tumors that…

Image and Video Processing · Electrical Eng. & Systems 2024-03-29 Qi Chen , Xiaoxi Chen , Haorui Song , Zhiwei Xiong , Alan Yuille , Chen Wei , Zongwei Zhou

Aside from offering state-of-the-art performance in medical image generation, denoising diffusion probabilistic models (DPM) can also serve as a representation learner to capture semantic information and potentially be used as an image…

Image and Video Processing · Electrical Eng. & Systems 2024-07-09 Chun-Mei Feng

We propose a novel pipeline for the generation of synthetic ultrasound images via Denoising Diffusion Probabilistic Models (DDPMs) guided by cardiac semantic label maps. We show that these synthetic images can serve as a viable substitute…

Image and Video Processing · Electrical Eng. & Systems 2023-08-16 David Stojanovski , Uxio Hermida , Pablo Lamata , Arian Beqiri , Alberto Gomez
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