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Microbiome data analysis is essential for understanding host health and disease, yet its inherent sparsity and noise pose major challenges for accurate imputation, hindering downstream tasks such as biomarker discovery. Existing imputation…

Machine Learning · Computer Science 2025-08-01 Rabeya Tus Sadia , Qiang Cheng

Cancer diagnosis, prognosis, and therapeutic response predictions are based on morphological information from histology slides and molecular profiles from genomic data. However, most deep learning-based objective outcome prediction and…

Computer Vision and Pattern Recognition · Computer Science 2020-09-04 Richard J. Chen , Ming Y. Lu , Jingwen Wang , Drew F. K. Williamson , Scott J. Rodig , Neal I. Lindeman , Faisal Mahmood

Removing the bias and variance of multicentre data has always been a challenge in large scale digital healthcare studies, which requires the ability to integrate clinical features extracted from data acquired by different scanners and…

Doctors often make diagonostic decisions based on patient's image scans, such as magnetic resonance imaging (MRI), and patient's electronic health records (EHR) such as age, gender, blood pressure and so on. Despite a lot of automatic…

Computer Vision and Pattern Recognition · Computer Science 2021-12-23 Cheng Jiang , Yihao Chen , Jianbo Chang , Ming Feng , Renzhi Wang , Jianhua Yao

Major pathological response (pR) following neoadjuvant therapy is a clinically meaningful endpoint in non-small cell lung cancer, strongly associated with improved survival. However, accurate preoperative prediction of pR remains…

Electronic Health Records (EHRs) have become increasingly popular to support clinical decision-making and healthcare in recent decades. EHRs usually contain heterogeneous information, such as structural data in tabular form and unstructured…

Machine Learning · Computer Science 2024-03-15 Hejie Cui , Xinyu Fang , Ran Xu , Xuan Kan , Joyce C. Ho , Carl Yang

Incomplete multi-modal medical image segmentation faces critical challenges from modality imbalance, including imbalanced modality missing rates and heterogeneous modality contributions. Due to their reliance on idealized assumptions of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-16 Libin Lan , Hongxing Li , Zunhui Xia , Yudong Zhang

As Vision-Language Models (VLMs) increasingly gain traction in medical applications, clinicians are progressively expecting AI systems not only to generate textual diagnoses but also to produce corresponding medical images that integrate…

Computer Vision and Pattern Recognition · Computer Science 2025-11-19 Junjie Yang , Yuhao Yan , Gang Wu , Yuxuan Wang , Ruoyu Liang , Xinjie Jiang , Xiang Wan , Fenglei Fan , Yongquan Zhang , Feiwei Qin , Changmiao Wang

Automatic radiology report generation can alleviate the workload for physicians and minimize regional disparities in medical resources, therefore becoming an important topic in the medical image analysis field. It is a challenging task, as…

Computer Vision and Pattern Recognition · Computer Science 2025-03-07 Xinyi Wang , Grazziela Figueredo , Ruizhe Li , Wei Emma Zhang , Weitong Chen , Xin Chen

Electronic health records arise from the complex interaction between patients and the healthcare system. This observation process of interactions, referred to as clinical presence, often impacts observed outcomes. When using electronic…

Machine Learning · Computer Science 2025-08-08 Vincent Jeanselme , Glen Martin , Matthew Sperrin , Niels Peek , Brian Tom , Jessica Barrett

Medical vision-language pretraining models (VLPM) have achieved remarkable progress in fusing chest X-rays (CXR) with clinical texts, introducing image-text data binding approaches that enable zero-shot learning and downstream clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yuan Gao , Sangwook Kim , David E Austin , Chris McIntosh

Recent advancements in multimodal foundation models have showcased impressive capabilities in understanding and reasoning with visual and textual information. Adapting these foundation models trained for general usage to specialized domains…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Hejie Cui , Lingjun Mao , Xin Liang , Jieyu Zhang , Hui Ren , Quanzheng Li , Xiang Li , Carl Yang

The joint interpretation of multi-modal and multi-view fundus images is critical for retinopathy prevention, as different views can show the complete 3D eyeball field and different modalities can provide complementary lesion areas. Compared…

Computer Vision and Pattern Recognition · Computer Science 2025-04-15 Yonghao Huang , Leiting Chen , Chuan Zhou

Visual transformers have driven major progress in remote sensing image analysis, particularly in object detection and segmentation. Recent vision-language and multimodal models further extend these capabilities by incorporating auxiliary…

Computer Vision and Pattern Recognition · Computer Science 2026-02-03 Yu Li , Guilherme N. DeSouza , Praveen Rao , Chi-Ren Shyu

Multimodal approaches that integrate histology and genomics hold strong potential for precision oncology. However, phenotypic and genotypic heterogeneity limits the quality of intra-modal representations and hinders effective inter-modal…

Computer Vision and Pattern Recognition · Computer Science 2025-12-01 Yupei Zhang , Yating Huang , Wanming Hu , Lequan Yu , Hujun Yin , Chao Li

Multimodal survival prediction, a crucial yet challenging task, demands the integration of multimodal medical data (\eg Whole Slide Images (WSIs) and Genomic Profiles) to achieve accurate prognostic modeling. Given the inherent…

Computer Vision and Pattern Recognition · Computer Science 2026-05-21 Huayi Wang , Haochao Ying , Yuyang Xu , Qiyao Zheng , jun wang , Cheng Zhang , Ying Sun , Jian Wu

Foundation models have become a promising paradigm for advancing medical image analysis, particularly for segmentation tasks where downstream applications often emerge sequentially. Existing fine-tuning strategies, however, remain limited:…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Yiwen Ye , Yicheng Wu , Xiangde Luo , He Zhang , Ziyang Chen , Ting Dang , Yanning Zhang , Yong Xia

Machine learning and deep learning methods have become essential for computer-assisted prediction in medicine, with a growing number of applications also in the field of mammography. Typically these algorithms are trained for a specific…

Image and Video Processing · Electrical Eng. & Systems 2021-12-03 Maria Wimmer , Gert Sluiter , David Major , Dimitrios Lenis , Astrid Berg , Theresa Neubauer , Katja Bühler

Cancer prognosis and survival outcome predictions are crucial for therapeutic response estimation and for stratifying patients into various treatment groups. Medical domains concerned with cancer prognosis are abundant with multiple…

Image and Video Processing · Electrical Eng. & Systems 2024-02-29 Ruining Deng , Nazim Shaikh , Gareth Shannon , Yao Nie

Multimodal semantic segmentation shows significant potential for enhancing segmentation accuracy in complex scenes. However, current methods often incorporate specialized feature fusion modules tailored to specific modalities, thereby…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Bingyu Li , Da Zhang , Zhiyuan Zhao , Junyu Gao , Xuelong Li