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Real-world problems are often dependent on multiple data modalities, making multimodal fusion essential for leveraging diverse information sources. In high-stakes domains, such as in healthcare, understanding how each modality contributes…

Neural and Evolutionary Computing · Computer Science 2025-05-19 Mafalda Malafaia , Thalea Schlender , Tanja Alderliesten , Peter A. N. Bosman

Multimodal clinical data are characterized by high dimensionality, heterogeneous representations, and structured missingness, posing significant challenges for predictive modeling, data integration, and interpretability. We propose BIONIC…

The integration of diverse clinical modalities such as medical imaging and the tabular data extracted from patients' Electronic Health Records (EHRs) is a crucial aspect of modern healthcare. Integrative analysis of multiple sources can…

Computer Vision and Pattern Recognition · Computer Science 2025-04-22 Daniel Duenias , Brennan Nichyporuk , Tal Arbel , Tammy Riklin Raviv

Secure and interoperable integration of heterogeneous medical data remains a grand challenge in digital health. Current federated learning (FL) frameworks offer privacy-preserving model training but lack standardized mechanisms to…

Cryptography and Security · Computer Science 2025-10-03 Aueaphum Aueawatthanaphisut

Healthcare systems generate diverse multimodal data, including Electronic Health Records (EHR), clinical notes, and medical images. Effectively leveraging this data for clinical prediction is challenging, particularly as real-world samples…

Machine Learning · Computer Science 2025-09-01 Xiaoyang Wang , Christopher C. Yang

Limited-angle computed tomography (LACT) offers improved temporal resolution and reduced radiation dose for cardiac imaging, but suffers from severe artifacts due to truncated projections. To address the ill-posedness of LACT…

Computer Vision and Pattern Recognition · Computer Science 2026-03-30 Yu Shi , Shuyi Fan , Changsheng Fang , Shuo Han , Haodong Li , Li Zhou , Bahareh Morovati , Dayang Wang , Hengyong Yu

As medical diagnoses increasingly leverage multimodal data, machine learning models are expected to effectively fuse heterogeneous information while remaining robust to missing modalities. In this work, we propose a novel multimodal…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Yi Gu , Kuniaki Saito , Jiaxin Ma

Machine learning methods in healthcare have traditionally focused on using data from a single modality, limiting their ability to effectively replicate the clinical practice of integrating multiple sources of information for improved…

Machine Learning · Computer Science 2024-02-13 Felix Krones , Umar Marikkar , Guy Parsons , Adam Szmul , Adam Mahdi

Routine clinical visits of a patient produce not only image data, but also non-image data containing clinical information regarding the patient, i.e., medical data is multi-modal in nature. Such heterogeneous modalities offer different and…

Computer Vision and Pattern Recognition · Computer Science 2023-03-16 Sein Kim , Namkyeong Lee , Junseok Lee , Dongmin Hyun , Chanyoung Park

Multi-modal medical imaging enables comprehensive diagnostics, yet current foundation models process 2D (e.g. X-ray) and 3D (e.g. CT) data with separate, dimensionality-specific architectures. We present MultiMedVision, a unified framework…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Frank Li , Bardia Khosravi , Mohammadreza Chavoshi , Young Seok Jeon , Theo Dapamede , Hari Trivedi , Janice Newsome , Judy Gichoya

Multi-modal medical image fusion (MMIF) is increasingly recognized as an essential technique for enhancing diagnostic precision and facilitating effective clinical decision-making within computer-aided diagnosis systems. MMIF combines data…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Muhammad Zubair , Muzammil Hussai , Mousa Ahmad Al-Bashrawi , Malika Bendechache , Muhammad Owais

As machine learning and artificial intelligence are more frequently being leveraged to tackle problems in the health sector, there has been increased interest in utilizing them in clinical decision-support. This has historically been the…

Machine Learning · Computer Science 2022-04-12 Adrienne Kline , Hanyin Wang , Yikuan Li , Saya Dennis , Meghan Hutch , Zhenxing Xu , Fei Wang , Feixiong Cheng , Yuan Luo

This research presents a novel multimodal data fusion methodology for pain behavior recognition, integrating statistical correlation analysis with human-centered insights. Our approach introduces two key innovations: 1) integrating…

Artificial Intelligence · Computer Science 2025-01-22 Xingrui Gu , Zhixuan Wang , Irisa Jin , Zekun Wu

Deep learning-based modeling of multimodal Electronic Health Records (EHRs) has become an important approach for clinical diagnosis and risk prediction. However, due to diverse clinical workflows and privacy constraints, raw EHRs are…

Machine Learning · Computer Science 2026-04-09 Bohao Li , Tao Zou , Junchen Ye , Yan Gong , Bowen Du

Foundation models in digital pathology use massive datasets to learn useful compact feature representations of complex histology images. However, there is limited transparency into what drives the correlation between dataset size and…

Clinical time series derived from electronic health records (EHRs) are inherently irregular, with asynchronous sampling, missing values, and heterogeneous feature dynamics. While numerical laboratory measurements are highly informative,…

Artificial Intelligence · Computer Science 2025-11-13 Yi-Hsien Hsieh , Ta-Jung Chien , Chun-Kai Huang , Shao-Hua Sun , Che Lin

Multimodal deep learning harnesses diverse imaging modalities, such as MRI sequences, to enhance diagnostic accuracy in medical imaging. A key challenge is determining the optimal timing for integrating these modalities-specifically,…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Valerio Guarrasi , Klara Mogensen , Sara Tassinari , Sara Qvarlander , Paolo Soda

Multimodal data modeling has emerged as a powerful approach in clinical research, enabling the integration of diverse data types such as imaging, genomics, wearable sensors, and electronic health records. Despite its potential to improve…

Multimodal fusion focuses on integrating information from multiple modalities with the goal of more accurate prediction, which has achieved remarkable progress in a wide range of scenarios, including autonomous driving and medical…

Machine Learning · Computer Science 2024-11-04 Qingyang Zhang , Yake Wei , Zongbo Han , Huazhu Fu , Xi Peng , Cheng Deng , Qinghua Hu , Cai Xu , Jie Wen , Di Hu , Changqing Zhang

Metadata are general characteristics of the data in a well-curated and condensed format, and have been proven to be useful for decision making, knowledge discovery, and also heterogeneous data organization of biobank. Among all data types…

Computer Vision and Pattern Recognition · Computer Science 2019-09-18 Wei-Hung Weng , Yuannan Cai , Angela Lin , Fraser Tan , Po-Hsuan Cameron Chen