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Existing depression screening predominantly relies on standardized questionnaires (e.g., PHQ-9, BDI), which suffer from high misdiagnosis rates (18-34% in clinical studies) due to their static, symptom-counting nature and susceptibility to…

Neurons and Cognition · Quantitative Biology 2025-04-24 Zhenguang Zhong , Zhixuan Wang

Depression remains widely underdiagnosed and undertreated because stigma and subjective symptom ratings hinder reliable screening. To address this challenge, we propose a coarse-to-fine, multi-stage framework that leverages large language…

Artificial Intelligence · Computer Science 2026-04-14 Shiyu Teng , Jiaqing Liu , Hao Sun , Yu Li , Shurong Chai , Ruibo Hou , Tomoko Tateyama , Lanfen Lin , Yen-Wei Chen

Depression is a growing concern gaining attention in both public discourse and AI research. While deep neural networks (DNNs) have been used for recognition, they still lack real-world effectiveness. Large language models (LLMs) show strong…

Human-Computer Interaction · Computer Science 2025-08-27 Yupei Li , Shuaijie Shao , Manuel Milling , Björn W. Schuller

Accurate and interpretable detection of depressive language in social media is useful for early interventions of mental health conditions, and has important implications for both clinical practice and broader public health efforts. In this…

Computation and Language · Computer Science 2025-06-10 Samuel Kim , Oghenemaro Imieye , Yunting Yin

Automated depression diagnosis aims to analyze multimodal information from interview videos to predict participants' depression scores. Previous studies often lack clear explanations of how these scores were determined, limiting their…

Artificial Intelligence · Computer Science 2026-03-19 Wei Zhang , Juan Chen , En Zhu , Wenhong Cheng , YunPeng Li , Yanbo J. Wang

Passively collected behavioral health data from ubiquitous sensors holds significant promise to provide mental health professionals insights from patient's daily lives; however, developing analysis tools to use this data in clinical…

Depression poses significant challenges to patients and healthcare organizations, necessitating efficient assessment methods. Existing paradigms typically focus on a patient-doctor way that overlooks multi-role interactions, such as family…

Human-Computer Interaction · Computer Science 2026-03-10 Zhiyuan Zhou , Jilong Liu , Sanwang Wang , Shijie Hao , Yanrong Guo , Richang Hong

The current work investigates the capability of Large language models (LLMs) that are explicitly trained on large corpuses of medical knowledge (Med-PaLM 2) to predict psychiatric functioning from patient interviews and clinical…

Computation and Language · Computer Science 2023-08-04 Isaac R. Galatzer-Levy , Daniel McDuff , Vivek Natarajan , Alan Karthikesalingam , Matteo Malgaroli

Depression remains a pressing global mental health issue, driving considerable research into AI-driven detection approaches. While pre-trained models, particularly speech self-supervised models (SSL Models), have been applied to depression…

Audio and Speech Processing · Electrical Eng. & Systems 2025-03-11 Xiangyu Zhang , Beena Ahmed , Julien Epps

Early detection of depression from social media data offers a valuable opportunity for timely intervention. However, this task poses significant challenges, requiring both professional medical knowledge and the development of accurate and…

Computation and Language · Computer Science 2025-03-20 Xiangyong Chen , Xiaochuan Lin

Major depressive disorder (MDD) impacts more than 300 million people worldwide, highlighting a significant public health issue. However, the uneven distribution of medical resources and the complexity of diagnostic methods have resulted in…

Computation and Language · Computer Science 2025-05-02 Yuyang Sha , Hongxin Pan , Wei Xu , Weiyu Meng , Gang Luo , Xinyu Du , Xiaobing Zhai , Henry H. Y. Tong , Caijuan Shi , Kefeng Li

This study investigates the use of Large Language Models (LLMs) for improved depression detection from users social media data. Through the use of fine-tuned GPT 3.5 Turbo 1106 and LLaMA2-7B models and a sizable dataset from earlier…

Computer Vision and Pattern Recognition · Computer Science 2024-09-24 Shahid Munir Shah , Syeda Anshrah Gillani , Mirza Samad Ahmed Baig , Muhammad Aamer Saleem , Muhammad Hamzah Siddiqui

This paper proposes a new depression detection system based on LLMs that is both interpretable and interactive. It not only provides a diagnosis, but also diagnostic evidence and personalized recommendations based on natural language…

Computation and Language · Computer Science 2023-05-10 Wei Qin , Zetong Chen , Lei Wang , Yunshi Lan , Weijieying Ren , Richang Hong

We employ a Large Language Model (LLM) to convert unstructured psychological interviews into structured questionnaires spanning various psychiatric and personality domains. The LLM is prompted to answer these questionnaires by impersonating…

Computation and Language · Computer Science 2024-06-12 Gony Rosenman , Lior Wolf , Talma Hendler

This study investigates clinicians' perceptions and attitudes toward an assistive artificial intelligence (AI) system that employs a speech-based explainable ML algorithm for detecting depression. The AI system detects depression from…

Human-Computer Interaction · Computer Science 2024-10-25 Kexin Feng , Theodora Chaspari

Anxiety and depression are the most common mental health issues worldwide, affecting a non-negligible part of the population. Accordingly, stakeholders, including governments' health systems, are developing new strategies to promote early…

Artificial Intelligence · Computer Science 2024-12-24 Francisco de Arriba-Pérez , Silvia García-Méndez

Depression is one of the most prevalent mental health disorders globally. In recent years, multi-modal data, such as speech, video, and transcripts, has been increasingly used to develop AI-assisted depression assessment systems. Large…

Depression is a widespread mental health disorder, and clinical interviews are the gold standard for assessment. However, their reliance on scarce professionals highlights the need for automated detection. Current systems mainly employ…

Computation and Language · Computer Science 2025-03-04 Linhai Zhang , Ziyang Gao , Deyu Zhou , Yulan He

Depression is one of the most prevalent and debilitating mental health conditions worldwide, frequently underdiagnosed and undertreated. The proliferation of social media platforms provides a rich source of naturalistic linguistic signals…

Computation and Language · Computer Science 2026-04-23 Giorgia Gulino , Manuel Petrucci

Users of social platforms often perceive these sites as supportive spaces to post about their mental health issues. Those conversations contain important traces about individuals' health risks. Recently, researchers have exploited this…

Computation and Language · Computer Science 2024-08-21 Eliseo Bao , Anxo Pérez , Javier Parapar
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