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A fundamental challenge in the empirical sciences involves uncovering causal structure through observation and experimentation. Causal discovery entails linking the conditional independence (CI) invariances in observational data to their…

Machine Learning · Statistics 2025-11-04 Zihan Zhou , Muhammad Qasim Elahi , Murat Kocaoglu

This article presents a novel method for causal discovery with generalized structural equation models suited for analyzing diverse types of outcomes, including discrete, continuous, and mixed data. Causal discovery often faces challenges…

Methodology · Statistics 2023-10-26 Minjie Wang , Xiaotong Shen , Wei Pan

Inferring causal structures from experimentation is a central task in many domains. For example, in biology, recent advances allow us to obtain single-cell expression data under multiple interventions such as drugs or gene knockouts.…

Machine Learning · Computer Science 2023-02-24 Alexander Hägele , Jonas Rothfuss , Lars Lorch , Vignesh Ram Somnath , Bernhard Schölkopf , Andreas Krause

Unmeasured confounding is a fundamental obstacle to causal inference from observational data. Latent-variable methods address this challenge by imputing unobserved confounders, yet many lack explicit model-based identification guarantees…

Computation · Statistics 2026-03-03 Yaxin Fang , Faming Liang

Latent confounding has been a long-standing obstacle for causal reasoning from observational data. One popular approach is to model the data using acyclic directed mixed graphs (ADMGs), which describe ancestral relations between variables…

Machine Learning · Computer Science 2023-03-23 Matthew Ashman , Chao Ma , Agrin Hilmkil , Joel Jennings , Cheng Zhang

Causal deep learning (CDL) is a new and important research area in the larger field of machine learning. With CDL, researchers aim to structure and encode causal knowledge in the extremely flexible representation space of deep learning…

Machine Learning · Computer Science 2022-12-05 Jeroen Berrevoets , Krzysztof Kacprzyk , Zhaozhi Qian , Mihaela van der Schaar

Directed acyclic graphs (DAGs) are central to science and engineering applications including causal inference, scheduling, and neural architecture search. In this work, we introduce the DAG Convolutional Network (DCN), a novel graph neural…

Signal Processing · Electrical Eng. & Systems 2026-05-20 Samuel Rey , Hamed Ajorlou , Gonzalo Mateos

Owing to the cross-pollination between causal discovery and deep learning, non-statistical data (e.g., images, text, etc.) encounters significant conflicts in terms of properties and methods with traditional causal data. To unify these data…

Machine Learning · Computer Science 2023-08-14 Hang Chen , Xinyu Yang , Qing Yang

Causal discovery algorithms aim at untangling complex causal relationships from data. Here, we study causal discovery and inference methods based on staged tree models, which can represent complex and asymmetric causal relationships between…

Methodology · Statistics 2023-03-02 Manuele Leonelli , Gherardo Varando

Learning causal relationships between variables is a well-studied problem in statistics, with many important applications in science. However, modeling real-world systems remain challenging, as most existing algorithms assume that the…

Biomarker discovery from high-throughput transcriptomic data is crucial for advancing precision medicine. However, existing methods often neglect gene-gene regulatory relationships and lack stability across datasets, leading to conflation…

Quantitative Methods · Quantitative Biology 2025-11-18 Chaowang Lan , Jingxin Wu , Yulong Yuan , Chuxun Liu , Huangyi Kang , Caihua Liu

Detecting unobserved confounders is crucial for reliable causal inference in observational studies. Existing methods require either linearity assumptions or multiple heterogeneous environments, limiting applicability to nonlinear…

Machine Learning · Statistics 2026-01-05 Yikai Chen , Yunxin Mao , Chunyuan Zheng , Hao Zou , Shanzhi Gu , Shixuan Liu , Yang Shi , Wenjing Yang , Kun Kuang , Haotian Wang

Despite their success and widespread adoption, the opaque nature of deep neural networks (DNNs) continues to hinder trust, especially in critical applications. Current interpretability solutions often yield inconsistent or oversimplified…

Machine Learning · Computer Science 2024-10-10 Alec F. Diallo , Vaishak Belle , Paul Patras

The discovery of causal relationships between random variables is an important yet challenging problem that has applications across many scientific domains. Differentiable causal discovery (DCD) methods are effective in uncovering causal…

Machine Learning · Computer Science 2024-10-29 Shiv Kampani , David Hidary , Constantijn van der Poel , Martin Ganahl , Brenda Miao

Causal discovery aims to recover graphs that represent causal relations among given variables from observations, and new methods are constantly being proposed. Increasingly, the community raises questions about how much progress is made,…

Machine Learning · Computer Science 2025-10-30 Zhufeng Li , Niki Kilbertus

We live in a world full of complex systems which we need to improve our understanding of. To accomplish this, purely probabilistic investigations are often not enough. They are only the first step and must be followed by learning the…

Machine Learning · Statistics 2024-12-24 Boris Lorbeer , Axel Küpper

Dynamic Uncertain Causality Graph(DUCG) is a recently proposed model for diagnoses of complex systems. It performs well for industry system such as nuclear power plants, chemical system and spacecrafts. However, the variable state…

Artificial Intelligence · Computer Science 2021-06-29 Hao Nie , Qin Zhang

Learning the unique directed acyclic graph corresponding to an unknown causal model is a challenging task. Methods based on functional causal models can identify a unique graph, but either suffer from the curse of dimensionality or impose…

Machine Learning · Computer Science 2025-01-14 Sujai Hiremath , Jacqueline R. M. A. Maasch , Mengxiao Gao , Promit Ghosal , Kyra Gan

This article proposes a novel causal discovery and inference method called GrIVET for a Gaussian directed acyclic graph with unmeasured confounders. GrIVET consists of an order-based causal discovery method and a likelihood-based…

Methodology · Statistics 2023-09-22 Li Chen , Chunlin Li , Xiaotong Shen , Wei Pan

Learning the dynamic causal structure of time series is a challenging problem. Most existing approaches rely on distributional or structural invariance to uncover underlying causal dynamics, assuming stationary or partially stationary…

Machine Learning · Computer Science 2026-02-27 Dezhi Yang , Qiaoyu Tan , Carlotta Domeniconi , Jun Wang , Lizhen Cui , Guoxian Yu