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We construct optimal designs for group testing experiments where the goal is to estimate the prevalence of a trait by using a test with uncertain sensitivity and specificity. Using optimal design theory for approximate designs, we show that…

Statistics Theory · Mathematics 2017-01-05 Shih-Hao Huang , Mong-Na Lo Huang , Kerby Shedden , Weng Kee Wong

Choosing an optimal strategy for hierarchical group testing is an important problem for practitioners who are interested in disease screening with limited resources. For example, when screening for infectious diseases in large populations,…

Methodology · Statistics 2020-02-27 Yaakov Malinovsky , Gregory Haber , Paul S. Albert

For large classes of group testing problems, we derive lower bounds for the probability that all significant items are uniquely identified using specially constructed random designs. These bounds allow us to optimize parameters of the…

Statistics Theory · Mathematics 2022-02-17 Jack Noonan , Anatoly Zhigljavsky

We have a large number of samples and we want to find the infected ones using as few number of tests as possible. We can use group testing which tells about a small group of people whether at least one of them is infected. Group testing is…

Quantitative Methods · Quantitative Biology 2020-05-07 Endre Csóka

In the group testing problem the aim is to identify a small set of $k\sim n^\theta$ infected individuals out of a population size $n$, $0<\theta<1$. We avail ourselves of a test procedure capable of testing groups of individuals, with the…

Discrete Mathematics · Computer Science 2021-05-14 Amin Coja-Oghlan , Oliver Gebhard , Max Hahn-Klimroth , Philipp Loick

Accurate detection of infected individuals is one of the critical steps in stopping any pandemic. When the underlying infection rate of the disease is low, testing people in groups, instead of testing each individual in the population, can…

Group testing is an efficient method for testing a large population to detect infected individuals. In this paper, we consider an efficient adaptive two stage group testing scheme. Using a straightforward analysis, we characterize the…

Methodology · Statistics 2020-08-26 Arjun Kodialam

This paper analytically investigates the optimal design of gamma degradation tests, including the number of test units, the number of inspections, and inspection times. We first derive optimal designs with periodic inspection times under…

Methodology · Statistics 2025-08-14 Hung-Ping Tung , Yu-Wen Chen

Consider a very large (infinite) population of items, where each item independent from the others is defective with probability p, or good with probability q=1-p. The goal is to identify N good items as quickly as possible. The following…

Other Statistics · Statistics 2018-04-17 Yaakov Malinovsky

We consider a new group testing model wherein each item is a binary random variable defined by an a priori probability of being defective. We assume that each probability is small and that items are independent, but not necessarily…

Information Theory · Computer Science 2018-07-24 Tongxin Li , Chun Lam Chan , Wenhao Huang , Tarik Kaced , Sidharth Jaggi

A central goal in designing clinical trials is to find the test that maximizes power (or equivalently minimizes required sample size) for finding a false null hypothesis subject to the constraint of type I error. When there is more than one…

Methodology · Statistics 2022-09-21 Ruth Heller , Abba Krieger , Saharon Rosset

When the infection prevalence of a disease is low, Dorfman showed 80 years ago that testing groups of people can prove more efficient than testing people individually. Our goal in this paper is to propose new group testing algorithms that…

Methodology · Statistics 2020-07-23 Marco Cuturi , Olivier Teboul , Quentin Berthet , Arnaud Doucet , Jean-Philippe Vert

We study the problem usually referred to as group testing in the context of COVID-19. Given $n$ samples taken from patients, how should we select mixtures of samples to be tested, so as to maximize information and minimize the number of…

Methodology · Statistics 2020-05-14 Louis Abraham , Gary Bécigneul , Bernhard Schölkopf

In this paper, we propose algorithms that leverage a known community structure to make group testing more efficient. We consider a population organized in connected communities: each individual participates in one or more communities, and…

Information Theory · Computer Science 2021-03-18 Pavlos Nikolopoulos , Sundara Rajan Srinivasavaradhan , Tao Guo , Christina Fragouli , Suhas Diggavi

In epidemic or pandemic situations, resources for testing the infection status of individuals may be scarce. Although group testing can help to significantly increase testing capabilities, the (repeated) testing of entire populations can…

Populations and Evolution · Quantitative Biology 2021-10-29 Günther Koliander , Georg Pichler

In the group testing problem we aim to identify a small number of infected individuals within a large population. We avail ourselves to a procedure that can test a group of multiple individuals, with the test result coming out positive iff…

Discrete Mathematics · Computer Science 2021-05-14 Amin Coja-Oghlan , Oliver Gebhard , Max Hahn-Klimroth , Philipp Loick

In group testing, the goal is to identify a subset of defective items within a larger set of items based on tests whose outcomes indicate whether any defective item is present. This problem is relevant in areas such as medical testing, data…

Information Theory · Computer Science 2020-11-11 Nelvin Tan , Jonathan Scarlett

In the group testing problem, the goal is to identify a subset of defective items within a larger set of items based on tests whose outcomes indicate whether any defective item is present. This problem is relevant in areas such as medical…

Information Theory · Computer Science 2022-09-28 Nelvin Tan , Way Tan , Jonathan Scarlett

The problem of Group Testing is to identify defective items out of a set of objects by means of pool queries of the form "Does the pool contain at least a defective?". The aim is of course to perform detection with the fewest possible…

Statistical Mechanics · Physics 2009-11-13 M. Mézard , M. Tarzia , C. Toninelli

Large scale disease screening is a complicated process in which high costs must be balanced against pressing public health needs. When the goal is screening for infectious disease, one approach is group testing in which samples are…

Applications · Statistics 2021-03-02 Gregory Haber , Yaakov Malinovsky , Paul S. Albert
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