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Artificial Intelligence is rapidly advancing and radically impacting everyday life, driven by the increasing availability of computing power. Despite this trend, the adoption of AI in real-world healthcare is still limited. One of the main…

Artificial Intelligence · Computer Science 2024-12-02 Akshat Dubey , Zewen Yang , Georges Hattab

Large language models (LLMs) excel at clinical information extraction but their computational demands limit practical deployment. Knowledge distillation--the process of transferring knowledge from larger to smaller models--offers a…

Computation and Language · Computer Science 2025-01-03 Karthik S. Vedula , Annika Gupta , Akshay Swaminathan , Ivan Lopez , Suhana Bedi , Nigam H. Shah

Explainable Artificial Intelligence has become a crucial area of research, aiming to demystify the decision-making processes of deep learning models. Among various explainability techniques, counterfactual explanations have been proven…

Machine Learning · Computer Science 2025-10-14 Flavio Giorgi , Matteo Silvestri , Cesare Campagnano , Fabrizio Silvestri , Gabriele Tolomei

As AI becomes fundamental in sectors like healthcare, explainable AI (XAI) tools are essential for trust and transparency. However, traditional user studies used to evaluate these tools are often costly, time consuming, and difficult to…

Artificial Intelligence · Computer Science 2024-10-24 Francesco Bombassei De Bona , Gabriele Dominici , Tim Miller , Marc Langheinrich , Martin Gjoreski

Despite strong performance in medical question-answering, the clinical adoption of Large Language Models (LLMs) is critically hampered by their opaque 'black-box' reasoning, limiting clinician trust. This challenge is compounded by the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Chao Ding , Mouxiao Bian , Pengcheng Chen , Hongliang Zhang , Tianbin Li , Lihao Liu , Jiayuan Chen , Zhuoran Li , Yabei Zhong , Yongqi Liu , Haiqing Huang , Dongming Shan , Junjun He , Jie Xu

Accurate clinical diagnosis requires extensive domain knowledge and complex clinical reasoning capabilities. Although large language models (LLMs) hold great potential for clinical reasoning, their high computational and memory requirements…

Computers and Society · Computer Science 2026-05-12 Xinchun Su , Chunxu Luo , Lipeng Ma , Yixuan Li , Weidong Yang

As the field of healthcare increasingly adopts artificial intelligence, it becomes important to understand which types of explanations increase transparency and empower users to develop confidence and trust in the predictions made by…

Artificial Intelligence · Computer Science 2025-05-16 Felix Liedeker , Olivia Sanchez-Graillet , Moana Seidler , Christian Brandt , Jörg Wellmer , Philipp Cimiano

Explainable Artificial Intelligence (XAI) addresses the growing need for transparency and interpretability in AI systems, enabling trust and accountability in decision-making processes. This book offers a comprehensive guide to XAI,…

Large Language Models (LLMs) offer a promising approach to enhancing Explainable AI (XAI) by transforming complex machine learning outputs into easy-to-understand narratives, making model predictions more accessible to users, and helping…

Artificial Intelligence · Computer Science 2025-04-02 Ahsan Bilal , David Ebert , Beiyu Lin

The growing application of artificial intelligence in sensitive domains has intensified the demand for systems that are not only accurate but also explainable and trustworthy. Although explainable AI (XAI) methods have proliferated, many do…

Artificial Intelligence · Computer Science 2026-01-06 Marilyn Bello , Rafael Bello , Maria-Matilde García , Ann Nowé , Iván Sevillano-García , Francisco Herrera

The detection of mental health problems from social media and the interpretation of these results have been extensively explored. Research has shown that incorporating clinical symptom information into a model enhances domain expertise,…

Computation and Language · Computer Science 2025-10-28 Hoyun Song , Huije Lee , Jisu Shin , Sukmin Cho , Changgeon Ko , Jong C. Park

Interpretation is critical for disease diagnosis, but existing models struggle to balance predictive accuracy with human-understandable rationales. While large language models (LLMs) offer strong reasoning abilities, their clinical use is…

Computation and Language · Computer Science 2025-07-15 Shuai Niu , Jing Ma , Hongzhan Lin , Liang Bai , Zhihua Wang , Yida Xu , Yunya Song , Xian Yang

Although machine learning (ML) models of AI achieve high performances in medicine, they are not free of errors. Empowering clinicians to identify incorrect model recommendations is crucial for engendering trust in medical AI. Explainable AI…

Artificial Intelligence · Computer Science 2022-12-20 Isil Guzey , Ozlem Ucar , Nukhet Aladag Ciftdemir , Betul Acunas

Explainable Artificial Intelligence (XAI) is a rising field in AI. It aims to produce a demonstrative factor of trust, which for human subjects is achieved through communicative means, which Machine Learning (ML) algorithms cannot solely…

Machine Learning · Computer Science 2021-03-09 Jamie Andrew Duell

The lack of transparency and explainability hinders the clinical adoption of Machine learning (ML) algorithms. While explainable artificial intelligence (XAI) methods have been proposed, little research has focused on the agreement between…

Machine Learning · Computer Science 2023-11-29 Aida Brankovic , Wenjie Huang , David Cook , Sankalp Khanna , Konstanty Bialkowski

Background: Despite the current ubiquity of Large Language Models (LLMs) across the medical domain, there is a surprising lack of studies which address their reasoning behaviour. We emphasise the importance of understanding reasoning…

Computation and Language · Computer Science 2025-07-29 Shamus Sim , Tyrone Chen

Interpretable machine learning aims to provide transparent models whose decision-making processes can be readily understood by humans. Recent advances in rule-based approaches, such as expressive Boolean formulas (BoolXAI), offer faithful…

Artificial Intelligence · Computer Science 2026-05-13 Du Cheng , Serdar Kadioglu , Xin Wang

Explainable AI (XAI) techniques are necessary to help clinicians make sense of AI predictions and integrate predictions into their decision-making workflow. In this work, we conduct a survey study to understand clinician preference among…

Computation and Language · Computer Science 2025-08-28 Jun Hou , Lucy Lu Wang

Deep learning models show significant potential for advancing AI-assisted medical diagnostics, particularly in detecting lung cancer through medical image modalities such as chest X-rays. However, the black-box nature of these models poses…

Machine Learning · Computer Science 2025-03-31 Amy Rafferty , Rishi Ramaesh , Ajitha Rajan

Large Language Models (LLMs) have demonstrated remarkable performance across a wide range of natural language processing tasks. However, their enormous parameter size and extremely high requirements for compute power pose challenges for…

Computation and Language · Computer Science 2024-03-26 Bohao Yang , Chen Tang , Kun Zhao , Chenghao Xiao , Chenghua Lin
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