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AI Foundation models are gaining traction in various applications, including medical fields like radiology. However, medical foundation models are often tested on limited tasks, leaving their generalisability and biases unexplored. We…

Brain MRI underpins a wide range of neuroscientific and clinical applications, yet most learning-based methods remain task-specific and require substantial labeled data. Here we show that a single self-supervised representation can…

Machine Learning · Computer Science 2026-05-27 Yizhou Wu , Shansong Wang , Yuheng Li , Mojtaba Safari , Mingzhe Hu , Chih-Wei Chang , Harini Veeraraghavan , Xiaofeng Yang

In hematology, computational models offer significant potential to improve diagnostic accuracy, streamline workflows, and reduce the tedious work of analyzing single cells in peripheral blood or bone marrow smears. However, clinical…

Computer Vision and Pattern Recognition · Computer Science 2024-04-09 Valentin Koch , Sophia J. Wagner , Salome Kazeminia , Ece Sancar , Matthias Hehr , Julia Schnabel , Tingying Peng , Carsten Marr

Foundation models have shown promise in medical imaging but remain underexplored for three-dimensional imaging modalities. No foundation model currently exists for Digital Breast Tomosynthesis (DBT), despite its use for breast cancer…

Skin diseases impose a substantial burden on global healthcare systems, driven by their high prevalence (affecting up to 70% of the population), complex diagnostic processes, and a critical shortage of dermatologists in resource-limited…

Foundation models in artificial intelligence (AI) are transforming medical imaging by enabling general-purpose feature learning from large-scale, unlabeled datasets. In this work, we introduce BrainFound, a self-supervised foundation model…

Computer Vision and Pattern Recognition · Computer Science 2026-01-01 Moona Mazher , Geoff J. M. Parker , Daniel C. Alexander

The integration of deep learning systems into healthcare has been hindered by the resource-intensive process of data annotation and the inability of these systems to generalize to different data distributions. Foundation models, which are…

Computer Vision and Pattern Recognition · Computer Science 2024-09-17 Mohammed Baharoon , Waseem Qureshi , Jiahong Ouyang , Yanwu Xu , Abdulrhman Aljouie , Wei Peng

Modeling of the red blood cell (RBC) shape is an integral part of the experimental and computer simulation investigations of light scattering by these cells for fundamental studies as well as diagnostic applications in techniques like…

Biological Physics · Physics 2024-06-18 Gaurav D. Bhabhor , Chetna Patel , Nishant Chhillar , Arun Anand , Kirit N. Lad

Digital pathology has recently been revolutionized by advancements in artificial intelligence, deep learning, and high-performance computing. With its advanced tools, digital pathology can help improve and speed up the diagnostic process,…

Image and Video Processing · Electrical Eng. & Systems 2024-03-28 Mohamed Elmanna , Ahmed Elsafty , Yomna Ahmed , Muhammad Rushdi , Ahmed Morsy

Remote sensing change detection (RSCD) aims to identify surface changes from co-registered bi-temporal images. However, many deep learning-based RSCD methods rely solely on change-map annotations and underuse the semantic information in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-21 Ching-Heng Cheng , Chih-Chung Hsu

The flow dynamics of red blood cells in vivo in blood capillaries and in vitro in microfluidic channels is complex. Cells can obtain differnet shapes such as discoid, parachute, slipper-like shapes and various intermediate states depending…

Biological Physics · Physics 2023-04-17 Andreas Link , a Irene Luna Pardo , Bernd Porr , Thomas Franke

Language-supervised pre-training has proven to be a valuable method for extracting semantically meaningful features from images, serving as a foundational element in multimodal systems within the computer vision and medical imaging domains.…

Bone marrow cell cytomorphology analysis is critical for the diagnosis of hematological malignancies but remains a labor-intensive process subject to significant inter-observer variability. While recent foundation models have shown promise…

Other Quantitative Biology · Quantitative Biology 2025-12-23 Aziz Muminov , Anne Pham

We present a rigorous procedure to derive coarse-grained red blood cell (RBC) models, which lead to accurate mechanical properties of realistic RBCs. Based on a semi-analytic theory linear and non-linear elastic properties of the RBC…

Cell Behavior · Quantitative Biology 2009-05-04 Dmitry A. Fedosov , Bruce Caswell , George E. Karniadakis

Skin cancer is one of the most prevalent and potentially life-threatening diseases worldwide, necessitating early and accurate diagnosis to improve patient outcomes. Conventional diagnostic methods, reliant on clinical expertise and…

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Recent breakthroughs in self-supervised learning have enabled the use of large unlabeled datasets to train visual foundation models that can generalize to a variety of downstream tasks. While this training paradigm is well suited for the…

Current self-supervised learning methods for 3D medical imaging rely on simple pretext formulations and organ- or modality-specific datasets, limiting their generalizability and scalability. We present 3DINO, a cutting-edge SSL method…

Image and Video Processing · Electrical Eng. & Systems 2025-01-22 Tony Xu , Sepehr Hosseini , Chris Anderson , Anthony Rinaldi , Rahul G. Krishnan , Anne L. Martel , Maged Goubran

Unsupervised graph representation learning has recently gained interest in several application domains such as neuroscience, where modeling the diverse morphology of cell types in the brain is one of the key challenges. It is currently…

Machine Learning · Statistics 2023-07-12 Marissa A. Weis , Laura Hansel , Timo Lüddecke , Alexander S. Ecker

Foundation vision models are increasingly adopted in medical image analysis. Due to domain shift, these pretrained models misalign with medical image segmentation needs without being fully fine-tuned or lightly adapted. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Zhuonan Liang , Wei Guo , Jie Gan , Yaxuan Song , Runnan Chen , Hang Chang , Weidong Cai

The advent of foundation models (FMs) is transforming medical domain. In ophthalmology, RETFound, a retina-specific FM pre-trained sequentially on 1.4 million natural images and 1.6 million retinal images, has demonstrated high adaptability…

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