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Diffusion MRI (dMRI) is an advanced imaging technique characterizing tissue microstructure and white matter structural connectivity of the human brain. The demand for high-quality dMRI data is growing, driven by the need for better…

Image and Video Processing · Electrical Eng. & Systems 2024-08-26 Xi Zhu , Wei Zhang , Yijie Li , Lauren J. O'Donnell , Fan Zhang

Diffusion MRI (dMRI) provides a distinctive means to probe the microstructural architecture of living tissue, facilitating applications such as brain connectivity analysis, modeling across multiple conditions, and the estimation of…

Image and Video Processing · Electrical Eng. & Systems 2025-11-20 Jongyeon Yoon , Elyssa M. McMaster , Michael E. Kim , Gaurav Rudravaram , Kurt G. Schilling , Bennett A. Landman , Daniel Moyer

Machine Learning (ML) is increasingly being used for computer aided diagnosis of brain related disorders based on structural magnetic resonance imaging (MRI) data. Most of such work employs biologically and medically meaningful hand-crafted…

Machine Learning · Computer Science 2018-05-04 Ayush Jaiswal , Dong Guo , Cauligi S. Raghavendra , Paul Thompson

Segmentation is one of the most important tasks in MRI medical image analysis and is often the first and the most critical step in many clinical applications. In brain MRI analysis, head segmentation is commonly used for measuring and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-11 Haleh Akrami , Wenhui Cui , Anand A Joshi , Richard M. Leahy

Brain segmentation is a fundamental first step in neuroimage analysis. In the case of fetal MRI, it is particularly challenging and important due to the arbitrary orientation of the fetus, organs that surround the fetal head, and…

Multimodal MRI offers complementary multi-scale information to characterize the brain structure. However, it remains challenging to effectively integrate multimodal MRI while achieving neuroscience interpretability. Here we propose to use…

Neurons and Cognition · Quantitative Biology 2025-12-15 Chengzhi Xia , Jianwei Chen , Yixuan Jiang , Qi Yan , Chao Li

Deep learning has a great potential for estimating biomarkers in diffusion weighted magnetic resonance imaging (dMRI). Atlases, on the other hand, are a unique tool for modeling the spatio-temporal variability of biomarkers. In this paper,…

Medical Physics · Physics 2022-05-09 Davood Karimi , Ali Gholipour

Finding an appropriate representation of dynamic activities in the brain is crucial for many downstream applications. Due to its highly dynamic nature, temporally averaged fMRI (functional magnetic resonance imaging) can only provide a…

Machine Learning · Computer Science 2022-08-18 Sikun Lin , Shuyun Tang , Scott Grafton , Ambuj Singh

Cytoarchitectonic mapping provides anatomically grounded parcellations of brain structure and forms a foundation for integrative, multi-modal neuroscience analyses. These parcellations are defined based on the shape, density, and spatial…

Image and Video Processing · Electrical Eng. & Systems 2026-01-16 Shiqi Zhang , Fang Xu , Pengcheng Zhou

The use of functional brain imaging for research and diagnosis has benefitted greatly from the recent advancements in neuroimaging technologies, as well as the explosive growth in size and availability of fMRI data. While it has been shown…

Data Structures and Algorithms · Computer Science 2017-08-10 Milad Makkie , Xiang Li , Binbin Lin , Jieping Ye , Mojtaba Sedigh Fazli , Tianming Liu , Shannon Quinn

Magnetic Resonance Imaging (MRI) of the brain has benefited from deep learning (DL) to alleviate the burden on radiologists and MR technologists, and improve throughput. The easy accessibility of DL tools have resulted in the rapid increase…

Image and Video Processing · Electrical Eng. & Systems 2023-01-04 Kunal Aggarwal , Marina Manso Jimeno , Keerthi Sravan Ravi , Gilberto Gonzalez , Sairam Geethanath

Nonrigid registration is vital to medical image analysis but remains challenging for diffusion MRI (dMRI) due to its high-dimensional, orientation-dependent nature. While classical methods are accurate, they are computationally demanding,…

Image and Video Processing · Electrical Eng. & Systems 2025-01-13 Gianfranco Cortes , Xiaoda Qu , Baba C. Vemuri

Segmentation of structural and diffusion MRI (sMRI/dMRI) is usually performed independently in neuroimaging pipelines. However, some brain structures (e.g., globus pallidus, thalamus and its nuclei) can be extracted more accurately by…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Juan Eugenio Iglesias , Koen Van Leemput , Polina Golland , Anastasia Yendiki

Recently, segmentation methods based on Convolutional Neural Networks (CNNs) showed promising performance in automatic Multiple Sclerosis (MS) lesions segmentation. These techniques have even outperformed human experts in controlled…

Image and Video Processing · Electrical Eng. & Systems 2021-07-26 Reda Abdellah Kamraoui , Vinh-Thong Ta , Thomas Tourdias , Boris Mansencal , José V Manjon , Pierrick Coupé

Diffusion probabilistic models (DPMs) have exhibited significant effectiveness in computer vision tasks, particularly in image generation. However, their notable performance heavily relies on labelled datasets, which limits their…

Computer Vision and Pattern Recognition · Computer Science 2024-05-09 Keqiang Fan , Xiaohao Cai , Mahesan Niranjan

Accurate automatic segmentation of brain anatomy from $T_1$-weighted~($T_1$-w) magnetic resonance images~(MRI) has been a computationally intensive bottleneck in neuroimaging pipelines, with state-of-the-art results obtained by unsupervised…

Computer Vision and Pattern Recognition · Computer Science 2018-08-01 Amod Jog , Bruce Fischl

Resting-state functional magnetic resonance imaging (rs-fMRI) is a noninvasive technique pivotal for understanding human neural mechanisms of intricate cognitive processes. Most rs-fMRI studies compute a single static functional…

Neurons and Cognition · Quantitative Biology 2025-02-25 Bishal Thapaliya , Robyn Miller , Jiayu Chen , Yu-Ping Wang , Esra Akbas , Ram Sapkota , Bhaskar Ray , Pranav Suresh , Santosh Ghimire , Vince Calhoun , Jingyu Liu

Diffusion Tensor Imaging (DTI) provides the possibility of estimating the location and course of eloquent structures in the human brain. Knowledge about this is of high importance for preoperative planning of neurosurgical interventions and…

Computer Vision and Pattern Recognition · Computer Science 2011-03-11 Miriam H. A. Bauer , Jan Egger , Daniela Kuhnt , Sebastiano Barbieri , Jan Klein , Horst K. Hahn , Bernd Freisleben , Christopher Nimsky

Accurate medical image segmentation is crucial for precise anatomical delineation. Deep learning models like U-Net have shown great success but depend heavily on large datasets and struggle with domain shifts, complex structures, and…

Computer Vision and Pattern Recognition · Computer Science 2025-03-11 Hantao Zhang , Yuhe Liu , Jiancheng Yang , Weidong Guo , Xinyuan Wang , Pascal Fua

In this paper, we present a fully automatic brain tumor segmentation and classification model using a Deep Convolutional Neural Network that includes a multiscale approach. One of the differences of our proposal with respect to previous…

Image and Video Processing · Electrical Eng. & Systems 2024-02-12 Francisco Javier Díaz-Pernas , Mario Martínez-Zarzuela , Míriam Antón-Rodríguez , David González-Ortega