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The advances in data, computing and networking over the last two decades led to a shift in many application domains that includes machine learning on big data as a part of the scientific process, requiring new capabilities for integrated…

Distributed, Parallel, and Cluster Computing · Computer Science 2019-03-19 Ilkay Altintas , Kyle Marcus , Isaac Nealey , Scott L. Sellars , John Graham , Dima Mishin , Joel Polizzi , Daniel Crawl , Thomas DeFanti , Larry Smarr

Catalytic processes are vital in the chemical industry, with nitrogen-to-ammonia conversion being a major industrial process. Designing catalysts relies on computational chemistry methods like Density Functional Theory (DFT), which have…

Scientific computing applications have benefited greatly from high performance computing infrastructure such as supercomputers. However, we are seeing a paradigm shift in the computational structure, design, and requirements of these…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-11-15 Prateek Sharma , Vikram Jadhao

To facilitate rational molecular and materials design, this research proposes an integrated computational framework that combines stochastic simulation, ab initio quantum chemistry, and molecular docking. The suggested workflow allows…

Materials Science · Physics 2026-01-08 Md Rakibul Karim Akanda , Michael P. Richard

We conducted quantum simulations of strongly correlated systems using the quantum flow (QFlow) approach, which enables sampling large sub-spaces of the Hilbert space through coupled eigenvalue problems in reduced dimensionality active…

Quantum Physics · Physics 2023-08-09 Karol Kowalski , Nicholas P. Bauman

The flow matching has rapidly become a dominant paradigm in classical generative modeling, offering an efficient way to interpolate between two complex distributions. We extend this idea to the quantum realm and introduce the Quantum Flow…

Quantum Physics · Physics 2026-02-03 Zidong Cui , Pan Zhang , Ying Tang

Quantum computing (QC) offers a new computing paradigm that has the potential to provide significant speedups over classical computing. Each additional qubit doubles the size of the computational state space available to a quantum…

Quantum Physics · Physics 2022-05-13 Wei Tang , Margaret Martonosi

High Performance Computing (HPC), Artificial Intelligence (AI)/Machine Learning (ML), and Quantum Computing (QC) and communications offer immense opportunities for innovation and impact on society. Researchers in these areas depend on…

Computers and Society · Computer Science 2020-12-18 William Gropp , Sujata Banerjee , Ian Foster

Quantitative investment aims to maximize the return and minimize the risk in a sequential trading period over a set of financial instruments. Recently, inspired by rapid development and great potential of AI technologies in generating…

General Finance · Quantitative Finance 2020-09-24 Xiao Yang , Weiqing Liu , Dong Zhou , Jiang Bian , Tie-Yan Liu

Quantum computing enables parallelism through superposition and entanglement and offers advantages over classical computing architectures. However, due to the limitations of current quantum hardware in the noisy intermediate-scale quantum…

Quantum Physics · Physics 2025-09-09 Guolong Zhong , Yi Fan , Zhenyu Li

Drug discovery is lengthy and expensive, with traditional computer-aided design facing limits. This paper examines integrating quantum computing across the drug development cycle to accelerate and enhance workflows and rigorous…

Research collaborations are continuously emerging catalyzed by online platforms, where people can share their codes, calculations, data and results. These virtual research platforms are innovative, community oriented, flexible and secure as…

While significant progress has been made on the hardware side of quantum computing, support for high-level quantum programming abstractions remains underdeveloped compared to classical programming languages. In this article, we introduce…

To harness the power of quantum computing (QC) in the near future, tight and efficient integration of QC with high performance computing (HPC) infrastructure (both on the software (SW) and the hardware (HW) level) is crucial. This paper…

Emerging Technologies · Computer Science 2024-07-29 Amr Elsharkawy , Xiaorang Guo , Martin Schulz

Fraunhofer FIRST develops a computing service and collaborative workspace providing a convenient tool for simulation and investigation of quantum algorithms. To broaden the twenty qubit limit of workstation-based simulations to the next…

Scientific communities naturally tend to organize around data ecosystems created by the combination of their observational devices, their data repositories, and the workflows essential to carry their research from observation to discovery.…

Networking and Internet Architecture · Computer Science 2021-06-30 Mark Asch , François Bodin , Micah Beck , Terry Moore , Michela Taufer , Martin Swany , Jean-Pierre Vilotte

The acceleration of materials discovery requires digital platforms that go beyond data repositories to embed learning, optimization, and decision-making directly into research workflows. We introduce DataScribe, an AI-native, cloud-based…

Machine Learning · Computer Science 2026-01-14 Divyanshu Singh , Doguhan Sarıtürk , Cameron Lea , Md Shafiqul Islam , Raymundo Arroyave , Vahid Attari

Experimental materials science is experiencing significant growth due to automated experimentation and AI techniques. Integrated autonomous platforms are emerging, combining generative models, robotics, simulations, and automated systems…

Software Engineering · Computer Science 2024-05-31 Amarnath Gupta , Shweta Purawat , Subhasis Dasgupta , Pratyush Karmakar , Elaine Chi , Ilkay Altintas

One of the most promising suggested applications of quantum computing is solving classically intractable chemistry problems. This may help to answer unresolved questions about phenomena like: high temperature superconductivity, solid-state…

Quantum Physics · Physics 2020-04-08 Sam McArdle , Suguru Endo , Alan Aspuru-Guzik , Simon Benjamin , Xiao Yuan

Accurate quantum chemistry simulations remain challenging on classical computers for problems of industrially relevant sizes and there is reason for hope that quantum computing may help push the boundaries of what is technically feasible.…

Quantum Physics · Physics 2021-03-17 Vincent E. Elfving , Marta Millaruelo , José A. Gámez , Christian Gogolin
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