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From social to biological systems, many real-world systems are characterized by higher-order, non-dyadic interactions. Such systems are conveniently described by hypergraphs, where hyperedges encode interactions among an arbitrary number of…

Cine magnetic resonance imaging (MRI) is the current gold standard for the assessment of cardiac anatomy and function. However, it typically only acquires a set of two-dimensional (2D) slices of the underlying three-dimensional (3D) anatomy…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Marcel Beetz , Abhirup Banerjee , Julius Ossenberg-Engels , Vicente Grau

A better fundamental understanding of human induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) has the potential to advance applications ranging from drug discovery to cardiac repair. Automated quantitative analysis of beating…

Quantitative Methods · Quantitative Biology 2021-11-17 Bill Zhao , Kehan Zhang , Christopher S. Chen , Emma Lejeune

The enhancement and detection of elongated structures in noisy image data is relevant for many biomedical imaging applications. To handle complex crossing structures in 2D images, 2D orientation scores $U: \mathbb{R} ^ 2\times S ^ 1…

Computer Vision and Pattern Recognition · Computer Science 2017-11-28 M. H. J. Janssen , A. J. E. M. Janssen , E. J. Bekkers , J. Olivan Bescos , R. Duits

Heart is one of the vital organs of human body. A minor dysfunction of heart even for a short time interval can be fatal, therefore, efficient monitoring of its physiological state is essential for the patients with cardiovascular diseases.…

Image and Video Processing · Electrical Eng. & Systems 2019-11-22 Shakeel Muhammad Ibrahim , Muhammad Sohail Ibrahim , Muhammad Usman , Imran Naseem , Muhammad Moinuddin

Accurate estimation of shape thickness from medical images is crucial in clinical applications. For example, the thickness of myocardium is one of the key to cardiac disease diagnosis. While mathematical models are available to obtain…

Image and Video Processing · Electrical Eng. & Systems 2020-08-26 Qiaoying Huang , Eric Z. Chen , Hanchao Yu , Yimo Guo , Terrence Chen , Dimitris Metaxas , Shanhui Sun

A holographic microscope captures interference patterns, or holograms, that encode three-dimensional (3D) information about the object being viewed. Computation is essential to extracting that 3D information. By wrapping low-level…

Image and Video Processing · Electrical Eng. & Systems 2018-06-04 Solomon Barkley , Thomas G. Dimiduk , Jerome Fung , David M. Kaz , Vinothan N. Manoharan , Ryan McGorty , Rebecca W. Perry , Anna Wang

Estimating the shape and motion state of the myocardium is essential in diagnosing cardiovascular diseases.However, cine magnetic resonance (CMR) imaging is dominated by 2D slices, whose large slice spacing challenges inter-slice shape…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Xiaohan Yuan , Cong Liu , Yangang Wang

The sharp rise in medical tomography examinations has created a demand for automated systems that can reliably extract informative features for downstream tasks such as tumor characterization. Although 3D volumes contain richer information…

Image and Video Processing · Electrical Eng. & Systems 2025-12-17 Johannes Kiechle , Stefan M. Fischer , Daniel M. Lang , Cosmin I. Bercea , Matthew J. Nyflot , Lina Felsner , Julia A. Schnabel , Jan C. Peeken

Deep learning-based cardiac segmentation has seen significant advancements over the years. Many studies have tackled the challenge of anatomically incorrect segmentation predictions by introducing auxiliary modules. These modules either…

Computer Vision and Pattern Recognition · Computer Science 2025-02-24 Zahid Ullah , Jihie Kim

Accurate ECG interpretation is vital, yet complex cardiac data and "black-box" AI models limit clinical utility. Inspired by Transformer architectures' success in NLP for understanding sequential data, we frame ECG as the heart's unique…

Signal Processing · Electrical Eng. & Systems 2025-06-09 Berat Kutay Uğraş , Ömer Nezih Gerek , İbrahim Talha Saygı

This article presents our steps to integrate complex and partly unstructured medical data into a clinical research database with subsequent decision support. Our main application is an integrated faceted search tool, accompanied by the…

Human-Computer Interaction · Computer Science 2018-10-31 Daniel Sonntag , Hans-Jürgen Profitlich

Information theory, i.e. the mathematical analysis of information and of its processing, has become a tenet of modern science; yet, its use in real-world studies is usually hindered by its computational complexity, the lack of coherent…

Physics and Society · Physics 2025-08-18 Carlson Moses Büth , Kishor Acharya , Massimiliano Zanin

Myocardial point tracking (MPT) has recently emerged as a promising direction for motion estimation in echocardiography, driven by advances in general-purpose point tracking methods. However, myocardial motion fundamentally differs from…

Computer Vision and Pattern Recognition · Computer Science 2026-05-13 Md Abulkalam Azad , Vegard Holmstrøm , John Nyberg , Lasse Lovstakken , Håvard Dalen , Bjørnar Grenne , Andreas Østvik

Purpose AI-based methods for anatomy segmentation can help automate characterization of large imaging datasets. The growing number of similar in functionality models raises the challenge of evaluating them on datasets that do not contain…

This article presents a dataset used in the article "Kinematics of Abdominal Aortic Aneurysms", published in the Journal of Biomechanics. The dataset is publicly available for download from the Zenodo data repository…

Global single-valued biomarkers of cardiac function typically used in clinical practice, such as ejection fraction, provide limited insight on the true 3D cardiac deformation process and hence, limit the understanding of both healthy and…

Image and Video Processing · Electrical Eng. & Systems 2023-07-21 Marcel Beetz , Abhirup Banerjee , Vicente Grau

Diffusion Tensor Cardiac Magnetic Resonance (DT-CMR) is the only in vivo method to non-invasively examine the microstructure of the human heart. Current research in DT-CMR aims to improve the understanding of how the cardiac microstructure…

Image and Video Processing · Electrical Eng. & Systems 2026-05-19 Yinzhe Wu , Jiahao Huang , Fanwen Wang , Pedro Ferreira , Andrew Scott , Sonia Nielles-Vallespin , Guang Yang

Echocardiography is routine for cardiac examination. However, 2D ultrasound (US) struggles with accurate metric calculation and direct observation of 3D cardiac structures. Moreover, 3D US is limited by low resolution, small field of view…

Predicting the structure of a protein from its sequence is a cornerstone task of molecular biology. Established methods in the field, such as homology modeling and fragment assembly, appeared to have reached their limit. However, this year…

Machine Learning · Computer Science 2018-12-05 Georgy Derevyanko , Guillaume Lamoureux