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Organ segmentation in CT volumes is an important pre-processing step in many computer assisted intervention and diagnosis methods. In recent years, convolutional neural networks have dominated the state of the art in this task. However,…

Protein-Protein Interactions (PPIs) perform essential roles in biological functions. Although some experimental techniques have been developed to detect PPIs, they suffer from high false positive and high false negative rates. Consequently,…

Video Anomaly Detection (VAD) involves detecting anomalous events in videos, presenting a significant and intricate task within intelligent video surveillance. Existing studies often concentrate solely on features acquired from limited…

Recently, probabilistic predictive coding that directly models the conditional distribution of latent features across successive frames for temporal redundancy removal has yielded promising results. Existing methods using a single-scale…

The generation of protein crystals is necessary for the study of protein molecular function and structure. This is done empirically by processing large numbers of crystallization trials and inspecting them regularly in search of those with…

Protein function and dynamics are closely related to its sequence and structure. However prediction of protein function and dynamics from its sequence and structure is still a fundamental challenge in molecular biology. Protein…

Recently, deep convolutional neural networks have shown good results for image recognition. In this paper, we use convolutional neural networks with a finder module, which discovers the important region for recognition and extracts that…

Learning effective protein representations is critical in a variety of tasks in biology such as predicting protein function or structure. Existing approaches usually pretrain protein language models on a large number of unlabeled amino acid…

Structural information about protein-protein interactions, often missing at the interactome scale, is important for mechanistic understanding of cells and rational discovery of therapeutics. Protein docking provides a computational…

Convolutional neural networks (CNNs) define the current state-of-the-art for image recognition. With their emerging popularity, especially for critical applications like medical image analysis or self-driving cars, confirmability is…

X-ray phase-contrast imaging offers enhanced sensitivity for weakly-attenuating materials, such as breast and brain tissue, but has yet to be widely implemented clinically due to high coherence requirements and expensive x-ray optics.…

Directed evolution is an iterative laboratory process of designing proteins with improved function by iteratively synthesizing new protein variants and evaluating their desired property with expensive and time-consuming biochemical…

Proteins are miniature machines whose function depends on their three-dimensional (3D) structure. Determining this structure computationally remains an unsolved grand challenge. A major bottleneck involves selecting the most accurate…

During the past decade, with the significant progress of computational power as well as ever-rising data availability, deep learning techniques became increasingly popular due to their excellent performance on computer vision problems. The…

Despite the great success of convolutional neural networks (CNN) for the image classification task on datasets like Cifar and ImageNet, CNN's representation power is still somewhat limited in dealing with object images that have large…

Designing protein sequences that fold into a target 3D structure, known as protein inverse folding, is a fundamental challenge in protein engineering. While recent deep learning methods have achieved impressive performance by recovering…

This work presents and analyzes three convolutional neural network (CNN) models for efficient pixelwise classification of images. When using convolutional neural networks to classify single pixels in patches of a whole image, a lot of…

This work introduces NeuroQuant, a novel post-training quantization (PTQ) approach tailored to non-generalized Implicit Neural Representations for variable-rate Video Coding (INR-VC). Unlike existing methods that require extensive weight…

MOTIVATION: Proteins fold into complex structures that are crucial for their biological functions. Experimental determination of protein structures is costly and therefore limited to a small fraction of all known proteins. Hence, different…

Parkinson's disease (PD) is a progressive neurodegenerative condition characterized by the death of dopaminergic neurons, leading to various movement disorder symptoms. Early diagnosis of PD is crucial to prevent adverse effects, yet…