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We propose the Multimodal Clinical Benchmark for Emergency Care (MC-BEC), a comprehensive benchmark for evaluating foundation models in Emergency Medicine using a dataset of 100K+ continuously monitored Emergency Department visits from…

Machine Learning · Computer Science 2023-11-10 Emma Chen , Aman Kansal , Julie Chen , Boyang Tom Jin , Julia Rachel Reisler , David A Kim , Pranav Rajpurkar

While Large Language Models (LLMs) achieve expert-level performance on standard medical benchmarks through single-hop factual recall, they severely struggle with the complex, multi-hop diagnostic reasoning required in real-world clinical…

Computation and Language · Computer Science 2026-03-16 Xing Zi , Xinying Zhou , Jinghao Xiao , Catarina Moreira , Mukesh Prasad

Deep Research Agents (DRAs) generate citation-rich reports via multi-step search and synthesis, yet existing benchmarks mainly target text-only settings or short-form multimodal QA, missing end-to-end multimodal evidence use. We introduce…

Computer Vision and Pattern Recognition · Computer Science 2026-01-21 Peizhou Huang , Zixuan Zhong , Zhongwei Wan , Donghao Zhou , Samiul Alam , Xin Wang , Zexin Li , Zhihao Dou , Li Zhu , Jing Xiong , Chaofan Tao , Yan Xu , Dimitrios Dimitriadis , Tuo Zhang , Mi Zhang

Multi-hop question answering (MQA) is one of the challenging tasks to evaluate machine's comprehension and reasoning abilities, where large language models (LLMs) have widely achieved the human-comparable performance. Due to the dynamics of…

Computation and Language · Computer Science 2024-02-16 Hengrui Gu , Kaixiong Zhou , Xiaotian Han , Ninghao Liu , Ruobing Wang , Xin Wang

Model editing aims to precisely alter the behaviors of large language models (LLMs) in relation to specific knowledge, while leaving unrelated knowledge intact. This approach has proven effective in addressing issues of hallucination and…

Computation and Language · Computer Science 2024-09-24 Derong Xu , Ziheng Zhang , Zhihong Zhu , Zhenxi Lin , Qidong Liu , Xian Wu , Tong Xu , Wanyu Wang , Yuyang Ye , Xiangyu Zhao , Enhong Chen , Yefeng Zheng

In recent years, AI models that mine intrinsic patterns from molecular structures and protein sequences have shown promise in accelerating drug discovery. However, these methods partly lag behind real-world pharmaceutical approaches of…

Machine Learning · Computer Science 2023-10-17 Yizhen Luo , Xing Yi Liu , Kai Yang , Kui Huang , Massimo Hong , Jiahuan Zhang , Yushuai Wu , Zaiqing Nie

Large language models (LLMs) encode vast amounts of world knowledge but remain static once trained, making the timely integration of emerging facts prohibitively expensive via full retraining. Knowledge-editing techniques have thus emerged…

Computation and Language · Computer Science 2025-09-03 Yuchen Wu , Liang Ding , Li Shen , Dacheng Tao

With the rapid growth of large language models (LLMs) and vision-language models (VLMs) in medicine, simply integrating clinical text and medical imaging does not guarantee reliable reasoning. Existing multimodal models often produce…

Artificial Intelligence · Computer Science 2025-12-29 Zelin Zang , Wenyi Gu , Siqi Ma , Dan Yang , Yue Shen , Zhu Zhang , Guohui Fan , Wing-Kuen Ling , Fuji Yang

Large language models (LLMs) are increasingly used as knowledge bases, but keeping them up to date requires targeted knowledge editing (KE). However, it remains unclear how edits are implemented inside the model once applied. In this work,…

Computation and Language · Computer Science 2026-03-24 Yuan Cao , Mingyang Wang , Hinrich Schütze

Recently, large language models (LLMs) have demonstrated impressive results but still suffer from hallucinations. Model editing has been proposed to correct factual inaccuracies in LLMs. A challenging case is sequential model editing (SME),…

Computation and Language · Computer Science 2025-06-24 Taolin Zhang , Haidong Kang , Dongyang Li , Qizhou Chen , Chengyu Wang Xiaofeng He , Richang Hong

Text-guided image editing has seen significant progress in natural image domains, but its application in medical imaging remains limited and lacks standardized evaluation frameworks. Such editing could revolutionize clinical practices by…

Computer Vision and Pattern Recognition · Computer Science 2025-10-07 Minghao Liu , Zhitao He , Zhiyuan Fan , Qingyun Wang , Yi R. Fung

Vision-Language Models (VLMs) have demonstrated remarkable progress in multimodal understanding, yet their capabilities for scientific reasoning remain inadequately assessed. Current multimodal benchmarks predominantly evaluate generic…

Computer Vision and Pattern Recognition · Computer Science 2025-06-18 Ai Jian , Weijie Qiu , Xiaokun Wang , Peiyu Wang , Yunzhuo Hao , Jiangbo Pei , Yichen Wei , Yi Peng , Xuchen Song

Computer-assisted diagnostic and prognostic systems of the future should be capable of simultaneously processing multimodal data. Multimodal deep learning (MDL), which involves the integration of multiple sources of data, such as images and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Zhaoyi Sun , Mingquan Lin , Qingqing Zhu , Qianqian Xie , Fei Wang , Zhiyong Lu , Yifan Peng

Large language models (LLMs) show significant potential in healthcare, prompting numerous benchmarks to evaluate their capabilities. However, concerns persist regarding the reliability of these benchmarks, which often lack clinical…

Computation and Language · Computer Science 2026-04-30 Wenting Chen , Guo Yu , Yiu-Fai Cheung , Meidan Ding , Jie Liu , Zizhan Ma , Wenxuan Wang , Linlin Shen

Multimodal Large Language Models are primarily trained and evaluated on aligned image-text pairs, which leaves their ability to detect and resolve real-world inconsistencies largely unexplored. In open-domain applications visual and textual…

Recent advances in multi-modal generative models have driven substantial improvements in image editing. However, current generative models still struggle with handling diverse and complex image editing tasks that require implicit reasoning,…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Feng Han , Yibin Wang , Chenglin Li , Zheming Liang , Dianyi Wang , Yang Jiao , Zhipeng Wei , Chao Gong , Cheng Jin , Jingjing Chen , Jiaqi Wang

The training of large language models (LLMs) necessitates substantial data and computational resources, and updating outdated LLMs entails significant efforts and resources. While numerous model editing techniques (METs) have emerged to…

Computation and Language · Computer Science 2024-02-06 Himanshu Beniwal , Kowsik Nandagopan D , Mayank Singh

Medical image analysis is essential to clinical diagnosis and treatment, which is increasingly supported by multi-modal large language models (MLLMs). However, previous research has primarily focused on 2D medical images, leaving 3D images…

Computer Vision and Pattern Recognition · Computer Science 2024-04-02 Fan Bai , Yuxin Du , Tiejun Huang , Max Q. -H. Meng , Bo Zhao

Model editing aims to correct inaccurate knowledge, update outdated information, and incorporate new data into Large Language Models (LLMs) without the need for retraining. This task poses challenges in lifelong scenarios where edits must…

Computation and Language · Computer Science 2025-03-17 Qizhou Chen , Chengyu Wang , Dakan Wang , Taolin Zhang , Wangyue Li , Xiaofeng He

Knowledge editing allows for efficient adaptation of large language models (LLMs) to new information or corrections without requiring full retraining. However, prior methods typically focus on either single-language editing or basic…

Computation and Language · Computer Science 2025-05-26 Yuchen Wu , Liang Ding , Li Shen , Dacheng Tao