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Quantum annealing provides a promising route for the development of quantum optimization devices, but the usefulness of such devices will be limited in part by the range of implementable problems as dictated by hardware constraints. To…

Quantum Physics · Physics 2015-10-14 Walter Vinci , Tameem Albash , Gerardo Paz-Silva , Itay Hen , Daniel A. Lidar

In this note, we describe an experiment on portfolio optimization using the Quadratic Unconstrained Binary Optimization (QUBO) formulation. The dataset we use is taken from a real-world problem for which a classical solution is currently…

The recent emergence of novel computational devices, such as quantum computers, coherent Ising machines, and digital annealers presents new opportunities for hardware-accelerated hybrid optimization algorithms. Unfortunately, demonstrations…

Optimization and Control · Mathematics 2020-10-21 Yuchen Pang , Carleton Coffrin , Andrey Y. Lokhov , Marc Vuffray

The Quadratic Unconstrained Binary Optimization (QUBO) model has gained prominence in recent years with the discovery that it unifies a rich variety of combinatorial optimization problems. By its association with the Ising problem in…

Data Structures and Algorithms · Computer Science 2019-11-06 Fred Glover , Gary Kochenberger , Yu Du

We explore the potential application of quantum annealing to address the protein structure problem. To this end, we compare several proposed ab initio protein folding models for quantum computers and analyze their scaling and performance…

Quantum Physics · Physics 2026-04-27 Timon Scheiber , Matthias Heller , Andreas Giebel

Stochastic Unit Commitment (SUC) has been proposed to manage the uncertainties driven by renewable integration, but it leads to significant computational complexity. When accelerated by Benders Decomposition (BD), the master problem becomes…

Quantum Physics · Physics 2026-02-25 Wei Hong , Wangkun Xu , Fei Teng

Protein folding is a central challenge in computational biology, with important applications in molecular biology, drug discovery and catalyst design. As a hard combinatorial optimisation problem, it has been studied as a potential target…

Assessing cyber risk in complex IT infrastructures poses significant challenges due to the dynamic, interconnected nature of digital systems. Traditional methods often fall short, relying on static and largely qualitative models that do not…

Quantum Physics · Physics 2026-04-22 Remo Marini , Riccardo Arpe

Clustering is a powerful machine learning technique that groups "similar" data points based on their characteristics. Many clustering algorithms work by approximating the minimization of an objective function, namely the sum of…

Quantum Physics · Physics 2018-01-29 Vaibhaw Kumar , Gideon Bass , Casey Tomlin , Joseph Dulny

Beam Placement (BP) is a well-known problem in Low-Earth Orbit (LEO) satellite communication (SatCom) systems, which can be modelled as an NP-hard clique cover problem. Recently, quantum computing has emerged as a novel technology which…

Information Theory · Computer Science 2022-10-13 Thinh Q. Dinh , Son Hoang Dau , Eva Lagunas , Symeon Chatzinotas

The even distribution and optimization of tasks across resources and workstations is a critical process in manufacturing aimed at maximizing efficiency, productivity, and profitability, known as Robotic Assembly Line Balancing (RALB). With…

Quantum Physics · Physics 2024-12-13 Moritz Willmann , Marcel Albus , Jan Schnabel , Marco Roth

Quadratic unconstrained binary optimization (QUBO) problems are well-studied, not least because they can be approached using contemporary quantum annealing or classical hardware acceleration. However, due to limited precision and hardware…

Quantum Physics · Physics 2023-07-06 Sascha Mücke , Thore Gerlach , Nico Piatkowski

Entanglement lies at the core of quantum algorithms designed to solve problems that are intractable by classical approaches. One such algorithm, quantum annealing (QA), provides a promising path to a practical quantum processor. We have…

Several combinatorial optimization problems can be solved with NISQ devices once that a corresponding quadratic unconstrained binary optimization (QUBO) form is derived. The aim of this work is to drastically reduce the variables needed for…

Quantum Physics · Physics 2026-02-25 Dario De Santis , Salvatore Tirone , Stefano Marmi , Vittorio Giovannetti

Quantum computers have the potential of solving problems more efficiently than classical computers. While first commercial prototypes have become available, the performance of such machines in practical application is still subject to…

Emerging Technologies · Computer Science 2020-05-13 Tom Krüger , Wolfgang Mauerer

Combinatorial optimization problems play a central role in computer science with many real world applications. A number of relevant problems remain computationally difficult to solve as they lie in the NP-hard complexity class. We present a…

Quantum Physics · Physics 2026-05-11 Kapil Goswami , Peter Schmelcher

A challenge for scalability of demand-responsive, elastic optical Dense Wavelength Division Multiplexing (DWDM) and Flexgrid networks is the computational complexity of allocating many optical routes on large networks. We demonstrate that…

Networking and Internet Architecture · Computer Science 2024-02-13 Ethan Davies , Darren Banfield , Vlad Carare , Ben Weaver , Catherine White , Nigel Walker

The Hubbard model has occupied the minds of condensed matter physicists for most part of the last century. This model provides insight into a range of phenomena in correlated electron systems. We wish to examine the paradigm of quantum…

Quantum Physics · Physics 2026-05-12 Kunal Vyas , Fengping Jin , Hans De Raedt , Kristel Michielsen

In this paper, we review some features of quantum annealing and related topics from viewpoints of statistical physics, condensed matter physics, and computational physics. We can obtain a better solution of optimization problems in many…

Disordered Systems and Neural Networks · Physics 2017-08-23 Shu Tanaka , Ryo Tamura

Quantum computers show potential for achieving computational advantage over classical computers, with many candidate applications in combinatorial optimisation. We present an application level benchmarking framework for near-term quantum…

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