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We present a machine learning method capable of accurately detecting chromosome abnormalities that cause blood cancers directly from microscope images of the metaphase stage of cell division. The pipeline is built on a series of fine-tuned…

Quality assurance is a critical but underexplored area in digital pathology, where even minor artifacts can have significant effects. Artifacts have been shown to negatively impact the performance of AI diagnostic models. In current…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Meredith VandeHaar , M. Clinch , I. Yilmaz , M. A. Rahman , Y. Xiao , F. Dogany , H. M. Alazab , A. Nassar , Z. Akkus , B. Dangott

An improved image mining technique for brain tumor classification using pruned association rule with MARI algorithm is presented in this paper. The method proposed makes use of association rule mining technique to classify the CT scan brain…

Computer Vision and Pattern Recognition · Computer Science 2010-01-13 P. Rajendran , M. Madheswaran

We present a novel spectral machine learning (SML) method in screening for pancreatic mass using CT imaging. Our algorithm is trained with approximately 30,000 images from 250 patients (50 patients with normal pancreas and 200 patients with…

Computer Vision and Pattern Recognition · Computer Science 2021-05-04 Yiming Liu , Ying Chen , Guangming Pan , Weichung Wang , Wei-Chih Liao , Yee Liang Thian , Cheng E. Chee , Constantinos P. Anastassiades

Artificial intelligence (AI) models trained using medical images for clinical tasks often exhibit bias in the form of disparities in performance between subgroups. Since not all sources of biases in real-world medical imaging data are…

Computer Vision and Pattern Recognition · Computer Science 2024-07-02 Emma A. M. Stanley , Raissa Souza , Anthony Winder , Vedant Gulve , Kimberly Amador , Matthias Wilms , Nils D. Forkert

Background: Accurate diagnosis of skull base tumors is essential for providing personalized surgical treatment strategies. Intraoperative diagnosis can be challenging due to tumor diversity and lack of intraoperative pathology resources.…

Aimed to develop and validate a CT radiomics-based explainable machine learning model for precise diagnosing malignancy and benignity specifically in endometrial cancer (EC) patients. A total of 83 EC patients from two centers, including 46…

Image and Video Processing · Electrical Eng. & Systems 2025-11-11 Tingrui Zhang , Honglin Wu , Zekun Jiang , Yingying Wang , Rui Ye , Huiming Ni , Chang Liu , Jin Cao , Xuan Sun , Rong Shao , Xiaorong Wei , Yingchun Sun

Thyroid cancer is common worldwide, with a rapid increase in prevalence across North America in recent years. While most patients present with palpable nodules through physical examination, a large number of small and medium-sized nodules…

Image and Video Processing · Electrical Eng. & Systems 2020-06-11 Fatemeh Abdolali , Atefeh Shahroudnejad , Abhilash Rakkunedeth Hareendranathan , Jacob L Jaremko , Michelle Noga , Kumaradevan Punithakumar

Recent advances in attention-based multiple instance learning (MIL) have improved our insights into the tissue regions that models rely on to make predictions in digital pathology. However, the interpretability of these approaches is still…

Quantitative Methods · Quantitative Biology 2023-09-11 Willem Bonnaffé , CRUK ICGC Prostate Group , Freddie Hamdy , Yang Hu , Ian Mills , Jens Rittscher , Clare Verrill , Dan J. Woodcock

Recognition of mitotic figures in histologic tumor specimens is highly relevant to patient outcome assessment. This task is challenging for algorithms and human experts alike, with deterioration of algorithmic performance under shifts in…

The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

In this paper we present an efficient computer aided mass classification method in digitized mammograms using Artificial Neural Network (ANN), which performs benign-malignant classification on region of interest (ROI) that contains mass.…

Computer Vision and Pattern Recognition · Computer Science 2010-07-30 Mohammed J. Islam , Majid Ahmadi , Maher A. Sid-Ahmed

Appropriate reliance is critical to achieving synergistic human-AI collaboration. For instance, when users over-rely on AI assistance, their human-AI team performance is bounded by the model's capability. This work studies how the…

Human-Computer Interaction · Computer Science 2024-01-17 Shiye Cao , Anqi Liu , Chien-Ming Huang

Gleason grading of prostate cancer is an important prognostic factor but suffers from poor reproducibility, particularly among non-subspecialist pathologists. Although artificial intelligence (A.I.) tools have demonstrated Gleason grading…

Purpose: In this work, we present a collaboration to create a validation dataset of pathologist annotations for algorithms that process whole slide images (WSIs). We focus on data collection and evaluation of algorithm performance in the…

Artificial intelligence (AI) classification holds promise as a novel and affordable screening tool for clinical management of ocular diseases. Rural and underserved areas, which suffer from lack of access to experienced ophthalmologists may…

Quantitative Methods · Quantitative Biology 2019-06-19 Minhaj Alam , David Le , Jennifer I. Lim , R. V. P. Chan , Xincheng Yao

In recent years, the field of medicine has been increasingly adopting artificial intelligence (AI) technologies to provide faster and more accurate disease detection, prediction, and assessment. In this study, we propose an interpretable AI…

The majority of cancer treatments end in failure due to Intra-Tumor Heterogeneity (ITH). ITH in cancer is represented by clonal evolution where different sub-clones compete with each other for resources under conditions of Darwinian natural…

The number of studies on deep learning for medical diagnosis is expanding, and these systems are often claimed to outperform clinicians. However, only a few systems have shown medical efficacy. From this perspective, we examine a wide range…

Image and Video Processing · Electrical Eng. & Systems 2023-04-04 Numan Saeed , Muhammad Ridzuan , Hussain Alasmawi , Ikboljon Sobirov , Mohammad Yaqub