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Grading precancerous lesions on whole slide images is a challenging task: the continuous space of morphological phenotypes makes clear-cut decisions between different grades often difficult, leading to low inter- and intra-rater agreements.…

Image and Video Processing · Electrical Eng. & Systems 2023-03-09 Mélanie Lubrano , Yaëlle Bellahsen-Harrar , Rutger Fick , Cécile Badoual , Thomas Walter

Purpose: Most studies evaluating artificial intelligence (AI) models that detect abnormalities in neuroimaging are either tested on unrepresentative patient cohorts or are insufficiently well-validated, leading to poor generalisability to…

Image and Video Processing · Electrical Eng. & Systems 2024-05-10 Siddharth Agarwal , David A. Wood , Mariusz Grzeda , Chandhini Suresh , Munaib Din , James Cole , Marc Modat , Thomas C Booth

Melanoma is the most malignant skin tumor and usually cancerates from normal moles, which is difficult to distinguish benign from malignant in the early stage. Therefore, many machine learning methods are trying to make auxiliary…

Image and Video Processing · Electrical Eng. & Systems 2022-04-22 Jiaqi Xue , Chentian Ma , Li Li , Xuan Wen

Computer-aided tumor detection has shown great potential in enhancing the interpretation of over 80 million CT scans performed annually in the United States. However, challenges arise due to the rarity of CT scans with tumors, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-09-11 Qi Chen , Yuxiang Lai , Xiaoxi Chen , Qixin Hu , Alan Yuille , Zongwei Zhou

Cases of laryngeal cancer are predicted to rise significantly in the coming years. Current diagnostic pathways are inefficient, putting undue stress on both patients and the medical system. Artificial intelligence offers a promising…

Sound · Computer Science 2025-05-14 Mary Paterson , James Moor , Luisa Cutillo

Despite the great promise that machine learning has offered in many fields of medicine, it has also raised concerns about potential biases and poor generalization across genders, age distributions, races and ethnicities, hospitals, and data…

Machine Learning · Computer Science 2023-02-01 Rongguang Wang , Pratik Chaudhari , Christos Davatzikos

Tumors can manifest in various forms and in different areas of the human body. Brain tumors are specifically hard to diagnose and treat because of the complexity of the organ in which they develop. Detecting them in time can lower the…

Image and Video Processing · Electrical Eng. & Systems 2024-03-18 Antonio Curci , Andrea Esposito

The past decade has witnessed a substantial increase in the number of startups and companies offering AI-based solutions for clinical decision support in medical institutions. However, the critical nature of medical decision-making raises…

Image and Video Processing · Electrical Eng. & Systems 2025-02-27 Solha Kang , Wesley De Neve , Francois Rameau , Utku Ozbulak

Mitotic activity is key for the assessment of malignancy in many tumors. Moreover, it has been demonstrated that the proportion of abnormal mitosis to normal mitosis is of prognostic significance. Atypical mitotic figures (MF) can be…

Computer Vision and Pattern Recognition · Computer Science 2022-12-13 Marc Aubreville , Jonathan Ganz , Jonas Ammeling , Taryn A. Donovan , Rutger H. J. Fick , Katharina Breininger , Christof A. Bertram

Alzheimer's Disease is challenging to diagnose due to our limited understanding of its mechanism and large heterogeneity among patients. Neurodegeneration is studied widely as a biomarker for clinical diagnosis, which can be measured from…

Machine Learning · Computer Science 2024-10-18 Rosemary He , Ichiro Takeuchi

Background: An increasing volume of prostate biopsies and a world-wide shortage of uro-pathologists puts a strain on pathology departments. Additionally, the high intra- and inter-observer variability in grading can result in over- and…

Purpose of review: Artificial intelligence (AI) has become popular in medical applications, specifically as a clinical support tool for computer-aided diagnosis. These tools are typically employed on medical data (i.e., image, molecular…

Machine Learning · Computer Science 2022-06-08 Ahmad Chaddad , Yousef Katib , Lama Hassan

Foundation models pretrained on large-scale pathology datasets have shown promising results across various diagnostic tasks. Here, we present a systematic evaluation of transfer learning strategies for brain tumor classification using these…

Image and Video Processing · Electrical Eng. & Systems 2025-04-09 Ken Enda , Yoshitaka Oda , Zen-ichi Tanei , Kenichi Satoh , Hiroaki Motegi , Terasaka Shunsuke , Shigeru Yamaguchi , Takahiro Ogawa , Wang Lei , Masumi Tsuda , Shinya Tanaka

Molecular classification has transformed the management of brain tumors by enabling more accurate prognostication and personalized treatment. However, timely molecular diagnostic testing for patients with brain tumors is limited,…

Melanoma is an aggressive neoplasm responsible for the majority of deaths from skin cancer. Specifically, spitzoid melanocytic tumors are one of the most challenging melanocytic lesions due to their ambiguous morphological features. The…

Image and Video Processing · Electrical Eng. & Systems 2021-04-21 Rocío del Amor , Laëtitia Launet , Adrián Colomer , Anaïs Moscardó , Andrés Mosquera-Zamudio , Carlos Monteagudo , Valery Naranjo

In the last decade, researchers working in the domain of computer vision and Artificial Intelligence (AI) have beefed up their efforts to come up with the automated framework that not only detects but also identifies stage of breast cancer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-10 Shahid Munir Shah , Rizwan Ahmed Khan , Sheeraz Arif , Unaiza Sajid

Accurate characterization of glioma is crucial for clinical decision making. A delineation of the tumor is also desirable in the initial decision stages but is a time-consuming task. Leveraging the latest GPU capabilities, we developed a…

Artificial intelligence (AI) systems have substantially improved dermatologists' diagnostic accuracy for melanoma, with explainable AI (XAI) systems further enhancing clinicians' confidence and trust in AI-driven decisions. Despite these…

Peripheral blood smears remain a cornerstone in the diagnosis of hematological neoplasms, offering rapid and valuable insights that inform subsequent diagnostic steps. However, since neoplastic transformations typically arise in the bone…

Despite the growing interest in human-AI decision making, experimental studies with domain experts remain rare, largely due to the complexity of working with domain experts and the challenges in setting up realistic experiments. In this…