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This paper introduces a novel magnetic navigation system for cardiac ablation. The system is formed from two key elements: a magnetic ablation catheter consisting of a chain of spherical permanent magnets; and an actuation system comprised…

Large-scale microfluidic microsystems with complex three-dimensional (3D) configurations are highly in demand by both fundamental research and industrial application, holding the potentials for fostering a wide range of innovative…

Applied Physics · Physics 2020-01-13 Zijie Lin , Jian Xu , Yunpeng Song , Xiaolong Li , Peng Wang , Wei Chu , Zhenhua Wang , Ya Cheng

For minimally invasive endovascular surgery, the localization of catheters and guidewires inside the human body is essential. Electromagnetic (EM) tracking is one technology that allows localizing such surgical instruments. For localizing…

The intricate morphology of brain vessels poses significant challenges for automatic segmentation models, which usually focus on a single imaging modality. However, accurately treating brain-related conditions requires a comprehensive…

Computer Vision and Pattern Recognition · Computer Science 2025-10-03 Francesco Galati , Daniele Falcetta , Rosa Cortese , Ferran Prados , Ninon Burgos , Maria A. Zuluaga

Endoscopic optical coherence tomography (OCT) is a valuable tool for providing diagnostic images of internal organs and guiding interventions in real time. Miniaturized OCT endoscopes are essential for imaging small and convoluted luminal…

Instrumentation and Detectors · Physics 2023-11-28 Chao Xu , Xin Guan , Syeda Aimen Abbasi , Neng Xia , To Ngai , Li Zhang , Ho-Pui Ho , Sze Hang Calvin Ng , Wu Yuan

Vascular anastomosis, the surgical connection of blood vessels, is essential in procedures such as organ transplants and reconstructive surgeries. The precision required limits accessibility due to the extensive training needed, with manual…

This paper presents a microfluidic device for magnetophoretic separation red blood cells from blood under contionous flow. The separation method consist of continous flow of a blood sample (diluted in PBS) through a microfluidic channel…

Other Computer Science · Computer Science 2008-12-18 Ciprian Iliescu , Elena Barbarini , Marioara Avram , G. Xu , Andrei Avram

We develop a general analytical and numerical framework for estimating intra- and extra-neurite water fractions and diffusion coefficients, as well as neurite orientational dispersion, in each imaging voxel. By employing a set of rotational…

Biological Physics · Physics 2018-04-10 Dmitry S. Novikov , Jelle Veraart , Ileana O. Jelescu , Els Fieremans

In biological microscopy, light scattering represents the main limitation to image at depth. Recently, a set of wavefront shaping techniques has been developed in order to manipulate coherent light in strongly disordered materials. The…

Optics · Physics 2021-01-07 Antoine Boniface , Jonathan Dong , Sylvain Gigan

While micro-CT systems are instrumental in preclinical research, clinical micro-CT imaging has long been desired with cochlear implantation as a primary example. The structural details of the cochlear implant and the temporal bone require a…

Automated detection and segmentation of surgical devices, such as catheters or wires, in X-ray fluoroscopic images have the potential to enhance image guidance in minimally invasive heart surgeries. In this paper, we present a convolutional…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Lin Xi , Yingliang Ma , Ethan Koland , Sandra Howell , Aldo Rinaldi , Kawal S. Rhode

Early detection of cancer is essential for timely diagnosis and improved patient outcomes. Among emerging technologies, intra-body nanoscale communication offers an innovative solution to identify molecular cues within the human…

Emerging Technologies · Computer Science 2026-03-12 Abdollah Rezagholi , Sergi Abadal , Filip Lemic , Eduard Alarcon , Ethungshan Shitiri

There has been a consistent growth in research involving imaging of microvasculature over the past few decades. By 2008, publications mentioning the microcirculation had grown more than 2000 per annum. Many techniques have been demonstrated…

Medical Physics · Physics 2019-07-04 Cerine Lal , Martin J Leahy

High-precision micromanipulation techniques, including optical tweezers and hydrodynamic trapping, have garnered wide-spread interest. Recent advances in optofluidic multiplexed assembly and microrobotics demonstrate significant progress,…

Fluid Dynamics · Physics 2025-11-03 Elena Erben , Ivan Saraev , Weida Liao , Fan Nan , Eric Lauga , Moritz Kreysing

Abdominal Aortic Aneurysms (AAA) are often repaired through an Endovascular approach known as EVAR. The success and duration of these challenging procedures are primarily attributable to the accuracy and reliability of navigating…

Medical Physics · Physics 2024-06-28 Yara Alawneh , James J. Zhou , Alykhan Sewani , Andrew Dueck , M. Ali Tavallaei

Augmented Reality (AR) surgical navigation systems are emerging as the next generation of intraoperative surgical guidance, promising to overcome limitations of traditional navigation systems. However, known issues with AR depth perception…

Computer Vision and Pattern Recognition · Computer Science 2025-08-19 Marc J. Fischer , Jeffrey Potts , Gabriel Urreola , Dax Jones , Paolo Palmisciano , E. Bradley Strong , Branden Cord , Andrew D. Hernandez , Julia D. Sharma , E. Brandon Strong

Minimally invasive robotic surgery has gained significant attention over the past two decades. Telerobotic systems, combined with robot-mediated minimally invasive techniques, have enabled surgeons and clinicians to mitigate radiation…

Intra-operative image guidance using magnetic resonance imaging (MRI) can significantly enhance the precision of surgical procedures, such as deep brain tumor ablation. However, the powerful magnetic fields and limited space within an MRI…

Robotics · Computer Science 2024-08-19 Zhanyue Zhao , Haimi Tang , Paulo Carvalho , Cosme Furlong , Gregory S. Fischer

Powered by acoustics, existing therapeutic and diagnostic procedures will become less invasive and new methods will become available that have never been available before. Acoustically driven microrobot navigation based on microbubbles is a…

Robotics · Computer Science 2023-08-04 Matthijs Schrage , Mahmoud Medany , Daniel Ahmed

Cerebral aneurysms and arteriovenous malformations are life-threatening hemodynamic pathologies of the brain. While surgical intervention is often essential to prevent fatal outcomes, it carries significant risks both during the procedure…

Machine Learning · Computer Science 2026-03-17 Irem Topal , Alexander Cherevko , Yuri Bugay , Maxim Shishlenin , Jean Barbier , Deniz Eroglu , Édgar Roldán , Roman Belousov
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