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Wiener and Granger have introduced an intuitive concept of causality between two variables which is based on the idea that an effect never occurs before its cause. Later, Geweke has generalized this concept to a multivariate Granger…

Extracting causal connections can advance interpretable AI and machine learning. Granger causality (GC) is a robust statistical method for estimating directed influences (DC) between signals. While GC has been widely applied to analysing…

Neurons and Cognition · Quantitative Biology 2024-08-06 Abdoreza Asadpour , KongFatt Wong-Lin

When a dynamical system can be modeled as a sequence of observations, Granger causality is a powerful approach for detecting predictive interactions between its variables. However, traditional Granger causal inference has limited utility in…

Machine Learning · Computer Science 2022-10-20 Rohit Singh , Alexander P. Wu , Bonnie Berger

There is a recent trend to leverage the power of graph neural networks (GNNs) for brain-network based psychiatric diagnosis, which,in turn, also motivates an urgent need for psychiatrists to fully understand the decision behavior of the…

Machine Learning · Statistics 2024-01-30 Kaizhong Zheng , Shujian Yu , Badong Chen

Human brain development is a complex and dynamic process that is affected by several factors such as genetics, sex hormones, and environmental changes. A number of recent studies on brain development have examined functional connectivity…

Computer Vision and Pattern Recognition · Computer Science 2020-01-29 Peyman Hosseinzadeh Kassani , Li Xiao , Gemeng Zhang , Julia M. Stephen , Tony W. Wilson , Vince D. Calhoun , Yu Ping Wang

Granger causality has been employed to investigate causality relations between components of stationary multiple time series. We generalize this concept by developing statistical inference for local Granger causality for multivariate…

Methodology · Statistics 2025-08-12 Yan Liu , Masanobu Taniguchi , Hernando Ombao

Neural processes in the brain operate at a range of temporal scales. Granger causality, the most widely-used neuroscientific tool for inference of directed functional connectivity from neurophsyiological data, is traditionally deployed in…

Applications · Statistics 2019-07-17 Lionel Barnett , Anil K. Seth

Granger-Geweke causality (GGC) is a powerful and popular method for identifying directed functional (`causal') connectivity in neuroscience. In a recent paper, Stokes and Purdon [1] raise several concerns about its use. They make two…

Methodology · Statistics 2018-02-07 Lionel Barnett , Adam B. Barrett , Anil K. Seth

Exploratory analysis of time series data can yield a better understanding of complex dynamical systems. Granger causality is a practical framework for analysing interactions in sequential data, applied in a wide range of domains. In this…

Machine Learning · Computer Science 2021-01-20 Ričards Marcinkevičs , Julia E. Vogt

This paper is motivated by studies in neuroscience experiments to understand interactions between nodes in a brain network using different types of data modalities that capture different distinct facets of brain activity. To assess…

We study the problem of learning Granger causality between event types from asynchronous, interdependent, multi-type event sequences. Existing work suffers from either limited model flexibility or poor model explainability and thus fails to…

Machine Learning · Computer Science 2020-02-20 Wei Zhang , Thomas Kobber Panum , Somesh Jha , Prasad Chalasani , David Page

Granger causal inference is a contentious but widespread method used in fields ranging from economics to neuroscience. The original definition addresses the notion of causality in time series by establishing functional dependence…

Methodology · Statistics 2023-09-19 Noah D. Gade , Jordan Rodu

Alzheimer's disease is the most common cause of dementia. It is the fifth-leading cause of death among elderly people. With high genetic heritability (79%), finding disease causal genes is a crucial step in find treatment for AD. Following…

Applications · Statistics 2018-11-14 Sicheng Hao , Rui Wang , Yu Zhang , Hui Zhan

This report reviews the conceptual and theoretical links between Granger causality and directed information theory. We begin with a short historical tour of Granger causality, concentrating on its closeness to information theory. The…

Information Theory · Computer Science 2015-06-12 Pierre-Olivier Amblard , Olivier J. J. Michel

Inferring causal relationships in observational time series data is an important task when interventions cannot be performed. Granger causality is a popular framework to infer potential causal mechanisms between different time series. The…

Machine Learning · Computer Science 2022-07-22 Zexuan Yin , Paolo Barucca

Granger causality analysis is a popular method for inference on directed interactions in complex systems of many variables. A shortcoming of the standard framework for Granger causality is that it only allows for examination of interactions…

Neurons and Cognition · Quantitative Biology 2010-04-14 Adam B. Barrett , Lionel Barnett , Anil K. Seth

This reply is in response to commentaries by Barnett, Barrett, and Seth (arXiv:1708.08001) and Faes, Stramaglia, and Marinazzo (arXiv:1708.06990) on our paper entitled "A study of problems encountered in Granger causality analysis from a…

Methodology · Statistics 2017-10-02 Patrick A. Stokes , Patrick L. Purdon

Concepts of Granger causality (GC) and Granger autonomy (GA) are central to assess the dynamics of coupled physiologic processes. While causality measures have been already proposed and applied in time and frequency domains, measures…

Signal Processing · Electrical Eng. & Systems 2023-07-20 Laura Sparacino , Yuri Antonacci , Chiara Barà , Angela Valenti , Alberto Porta , Luca Faes

A novel approach is developed for discovering directed connectivity between specified pairs of nodes in a high-dimensional network (HDN) of brain signals. To accurately identify causal connectivity for such specified objectives, it is…

Applications · Statistics 2025-05-06 Sipan Aslan , Hernando Ombao

Multi-electrode neurophysiological recordings produce massive quantities of data. Multivariate time series analysis provides the basic framework for analyzing the patterns of neural interactions in these data. It has long been recognized…

Quantitative Methods · Quantitative Biology 2007-05-23 Mingzhou Ding , Yonghong Chen , Steven L. Bressler
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