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Current cervical cytopathology whole slide image (WSI) screening primarily relies on detection-based approaches, which are limited in performance due to the expense and time-consuming annotation process. Multiple Instance Learning (MIL), a…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Jialong Huang , Gaojie Li , Shichao Kan , Jianfeng Liu , Yixiong Liang

Multiple instance learning (MIL) stands as a powerful approach in weakly supervised learning, regularly employed in histological whole slide image (WSI) classification for detecting tumorous lesions. However, existing mainstream MIL methods…

Image and Video Processing · Electrical Eng. & Systems 2024-07-08 Wenhui Zhu , Xiwen Chen , Peijie Qiu , Aristeidis Sotiras , Abolfazl Razi , Yalin Wang

Knowledge Distillation (KD) has been used in image classification for model compression. However, rare studies apply this technology on single-stage object detectors. Focal loss shows that the accumulated errors of easily-classified samples…

Computer Vision and Pattern Recognition · Computer Science 2019-01-15 Shitao Tang , Litong Feng , Wenqi Shao , Zhanghui Kuang , Wei Zhang , Yimin Chen

In computational pathology, random sampling of patches during training of Multiple Instance Learning (MIL) methods is computationally efficient and serves as a regularization strategy. Despite its promising benefits, questions concerning…

Computer Vision and Pattern Recognition · Computer Science 2024-03-11 H. Keshvarikhojasteh , J. P. W. Pluim , M. Veta

Multiple Instance Learning (MIL) has been widely applied to medical imaging diagnosis, where bag labels are known and instance labels inside bags are unknown. Traditional MIL assumes that instances in each bag are independent samples from a…

Image and Video Processing · Electrical Eng. & Systems 2023-07-19 Yunan Wu , Francisco M. Castro-Macías , Pablo Morales-Álvarez , Rafael Molina , Aggelos K. Katsaggelos

Diffusion models produce high-quality text-to-image results, but their iterative denoising is computationally expensive.Distribution Matching Distillation (DMD) emerges as a promising path to few-step distillation, but suffers from…

Computer Vision and Pattern Recognition · Computer Science 2026-04-07 Haoyu Li , Tingyan Wen , Lin Qi , Zhe Wu , Yihuang Chen , Xing Zhou , Lifei Zhu , Xueqian Wang , Kai Zhang

The development of computer vision solutions for gigapixel images in digital pathology is hampered by significant computational limitations due to the large size of whole slide images. In particular, digitizing biopsies at high resolutions…

Computer Vision and Pattern Recognition · Computer Science 2024-01-12 Rocío del Amor , Julio Silva-Rodríguez , Adrián Colomer , Valery Naranjo

The recent surge of pervasive devices that generate dynamic data streams has underscored the necessity for learning systems to adapt continually to data distributional shifts. To tackle this challenge, the research community has put forth a…

Computer Vision and Pattern Recognition · Computer Science 2023-12-21 Jacopo Bonato , Francesco Pelosin , Luigi Sabetta , Alessandro Nicolosi

Whole slide images (WSIs) are gigapixel-scale digital images of H\&E-stained tissue samples widely used in pathology. The substantial size and complexity of WSIs pose unique analytical challenges. Multiple Instance Learning (MIL) has…

Computer Vision and Pattern Recognition · Computer Science 2024-08-20 Jun Wang , Yu Mao , Nan Guan , Chun Jason Xue

Whole-slide image (WSI) classification in computational pathology is commonly formulated as slide-level Multiple Instance Learning (MIL) with a single global bag representation. However, slide-level MIL is fundamentally underconstrained:…

Computer Vision and Pattern Recognition · Computer Science 2026-04-15 Syed Fahim Ahmed , Gnanesh Rasineni , Florian Koehler , Abu Zahid Bin Aziz , Mei Wang , Attila Gyulassy , Brian Summa , J. Quincy Brown , Valerio Pascucci , Shireen Y. Elhabian

Whole slide image (WSI) classification is a fundamental task for the diagnosis and treatment of diseases; but, curation of accurate labels is time-consuming and limits the application of fully-supervised methods. To address this, multiple…

Computer Vision and Pattern Recognition · Computer Science 2022-07-25 Philip Chikontwe , Soo Jeong Nam , Heounjeong Go , Meejeong Kim , Hyun Jung Sung , Sang Hyun Park

Whole-slide images (WSIs) are an important data modality in computational pathology, yet their gigapixel resolution and lack of fine-grained annotations challenge conventional deep learning models. Multiple instance learning (MIL) offers a…

Computer Vision and Pattern Recognition · Computer Science 2025-12-22 Qian Zeng , Yihui Wang , Shu Yang , Yingxue Xu , Fengtao Zhou , Jiabo Ma , Dejia Cai , Zhengyu Zhang , Lijuan Qu , Yu Wang , Li Liang , Hao Chen

Dataset distillation (DD) aims to minimize the time and memory consumption needed for training deep neural networks on large datasets, by creating a smaller synthetic dataset that has similar performance to that of the full real dataset.…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Xinhao Zhong , Bin Chen , Hao Fang , Xulin Gu , Shu-Tao Xia , En-Hui Yang

High-quality annotation of fine-grained visual categories demands great expert knowledge, which is taxing and time consuming. Alternatively, learning fine-grained visual representation from enormous unlabeled images (e.g., species, brands)…

Computer Vision and Pattern Recognition · Computer Science 2025-06-25 Qi Bi , Wei Ji , Jingjun Yi , Haolan Zhan , Gui-Song Xia

The inference latency of diffusion models remains a critical barrier to their real-time application. While trajectory-based and distribution-based step distillation methods offer solutions, they present a fundamental trade-off.…

Computer Vision and Pattern Recognition · Computer Science 2025-11-13 Hanbo Cheng , Peng Wang , Kaixiang Lei , Qi Li , Zhen Zou , Pengfei Hu , Jun Du

Discrete diffusion models (DDMs) have shown powerful generation ability for discrete data modalities like text and molecules. However, their practical application is hindered by inefficient sampling, requiring a large number of sampling…

Machine Learning · Computer Science 2025-09-25 Feiyang Fu , Tongxian Guo , Zhaoqiang Liu

Hierarchical Imitation Learning (HIL) is an effective way for robots to learn sub-skills from long-horizon unsegmented demonstrations. However, the learned hierarchical structure lacks the mechanism to transfer across multi-tasks or to new…

Robotics · Computer Science 2022-02-22 Chongkai Gao , Yizhou Jiang , Feng Chen

Dataset distillation compresses large training sets into compact synthetic datasets while preserving downstream performance. As modern systems increasingly operate on paired vision-language inputs, multimodal distillation must preserve…

Computer Vision and Pattern Recognition · Computer Science 2026-05-25 Jongoh Jeong , Hoyong Kwon , Minseok Kim , Kuk-Jin Yoon

Distribution Matching Distillation (DMD) is a widely used paradigm for accelerating inference in few-step video diffusion models. However, DMD-style video distillation faces two coupled challenges: the fake score must track a continuously…

Computer Vision and Pattern Recognition · Computer Science 2026-05-29 Zhuguanyu Wu , Ruihao Gong , Yang Yong , Yushi Huang , Xiangyu Fan , Lei Yang , Dahua Lin , Xianglong Liu

Treatment approaches for colorectal cancer (CRC) are highly dependent on the molecular subtype, as immunotherapy has shown efficacy in cases with microsatellite instability (MSI) but is ineffective for the microsatellite stable (MSS)…

Computer Vision and Pattern Recognition · Computer Science 2024-11-13 Hadar Hezi , Matan Gelber , Alexander Balabanov , Yosef E. Maruvka , Moti Freiman