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Deep feedforward and recurrent rate-based neural networks have become successful functional models of the brain, but they neglect obvious biological details such as spikes and Dale's law. Here we argue that these details are crucial in…

Neurons and Cognition · Quantitative Biology 2023-12-29 William F. Podlaski , Christian K. Machens

Epilepsy is a neurological disease characterized by recurrent and spontaneous seizures. It affects approximately 50 million people worldwide. In majority of the cases accurate diagnosis of the disease can be made without using any…

Quantitative Methods · Quantitative Biology 2013-04-05 Roxana A. Stephanescu , R. G. Shivakeshavan , Sachin S. Talathi

Recurrent Neural Networks (RNNs) with sophisticated units that implement a gating mechanism have emerged as powerful technique for modeling sequential signals such as speech or electroencephalography (EEG). The latter is the focus on this…

Signal Processing · Electrical Eng. & Systems 2018-01-09 Meysam Golmohammadi , Saeedeh Ziyabari , Vinit Shah , Eva Von Weltin , Christopher Campbell , Iyad Obeid , Joseph Picone

A seizure's electrographic dynamics are characterised by its spatiotemporal evolution, also termed dynamical "pathway" and the time it takes to complete that pathway, which results in the seizure's duration. Both seizure pathways and…

There is a ongoing debate whether generic early warning signals for critical transitions exist that can be applied across diverse systems. The human epileptic brain is often considered as a prototypical system, given the devastating and, at…

Medical Physics · Physics 2019-10-23 Theresa Wilkat , Thorsten Rings , Klaus Lehnertz

A Magnetoencephalography (MEG) time-series recording consists of multi-channel signals collected by superconducting sensors, with each signal's intensity reflecting magnetic field changes over time at the sensor location. Automating…

Signal Processing · Electrical Eng. & Systems 2025-01-22 Hanyang Dong , Shurong Sheng , Xiongfei Wang , Jiahong Gao , Yi Sun , Wanli Yang , Kuntao Xiao , Pengfei Teng , Guoming Luan , Zhao Lv

The human brain receives complex inputs when performing cognitive tasks, which range from external inputs via the senses to internal inputs from other brain regions. However, the explicit inputs to the brain during a cognitive task remain…

Neurons and Cognition · Quantitative Biology 2024-04-26 Zhichao Liang , Yinuo Zhang , Jushen Wu , Quanying Liu

Mental disorders may exhibit pathological brain rhythms and neurostimulation promises to alleviate of patients' symptoms by modifying these rhythms. Today, most neurostimulation schemes are open-loop, i.e. administer experimental…

Neurons and Cognition · Quantitative Biology 2023-03-21 Thomas Wahl , Michel Duprez , Axel Hutt

Since the first recordings made of evoked action potentials it has become apparent that the responses of individual neurons to ongoing physiologically relevant input, are highly variable. This variability is manifested in non-stationary…

Neurons and Cognition · Quantitative Biology 2010-08-10 Avner Wallach , Danny Eytan , Asaf Gal , Christoph Zrenner , Ron Meir , Shimon Marom

Balance of excitation and inhibition is a fundamental feature of in vivo network activity and is important for its computations. However, its presence in the neocortex of higher mammals is not well established. We investigated the dynamics…

The information of spiking neural networks (SNNs) are propagated between the adjacent biological neuron by spikes, which provides a computing paradigm with the promise of simulating the human brain. Recent studies have found that the time…

Neural and Evolutionary Computing · Computer Science 2022-05-05 Pengfei Sun , Longwei Zhu , Dick Botteldooren

Visually induced neuronal activity in V1 displays a marked gamma-band component which is modulated by stimulus properties. It has been argued that synchronized oscillations contribute to these gamma-band activity [... however,] even when…

Neurons and Cognition · Quantitative Biology 2011-12-20 Demian Battaglia , David Hansel

Spiking neural networks (SNNs) are biologically inspired, event-driven models suited for temporal data processing and energy-efficient neuromorphic computing. In SNNs, richer neuronal dynamic allows capturing more complex temporal…

Machine Learning · Computer Science 2026-03-27 Sanja Karilanova , Subhrakanti Dey , Ayça Özçelikkale

What input signals will lead to synchrony vs. desynchrony in a group of biological oscillators? This question connects with both classical dynamical systems analyses of entrainment and phase locking and with emerging studies of stimulation…

Dynamical Systems · Mathematics 2015-03-17 Guillaume Lajoie , Eric Shea-Brown

Time--delayed feedback is exploited for controlling noise--induced motion in coherence resonance oscillators. Namely, under the proper choice of time delay, one can either increase or decrease the regularity of motion. It is shown that in…

Statistical Mechanics · Physics 2009-11-10 N. B. Janson , A. G. Balanov , E. Schoell

Epilepsy is a disorder of the nervous system that can affect people of any age group. With roughly 50 million people worldwide diagnosed with the disorder, it is one of the most common neurological disorders. The EEG is an indispensable…

Populations and Evolution · Quantitative Biology 2022-02-21 Niamh McCallan , Scot Davidson , Kok Yew Ng , Pardis Biglarbeigi , Dewar Finlay , Boon Leong Lan , James McLaughlin

Seizure events can manifest as transient disruptions in the control of movements which may be organized in distinct behavioral sequences, accompanied or not by other observable features such as altered facial expressions. The analysis of…

Computer Vision and Pattern Recognition · Computer Science 2024-03-05 David Ahmedt-Aristizabal , Mohammad Ali Armin , Zeeshan Hayder , Norberto Garcia-Cairasco , Lars Petersson , Clinton Fookes , Simon Denman , Aileen McGonigal

Biological neural networks can operate in qualitatively distinct dynamical regimes, and transitions between these regimes are thought to underlie changes in computation and behavior. The seminal work of Sompolinsky, Crisanti, and Sommers…

Disordered Systems and Neural Networks · Physics 2026-05-15 Carles Martorell , Rubén Calvo , Alessia Annibale , Miguel A. Muñoz

Although recent studies have proposed seizure detection algorithms with good sensitivity performance, there is a remained challenge that they were hard to achieve significantly short detection latency in real-time scenarios. In this…

Signal Processing · Electrical Eng. & Systems 2023-06-29 Yankun Xu , Jie Yang , Wenjie Ming , Shuang Wang , Mohamad Sawan

Objective: Forecasting epileptic seizures can reduce uncertainty for patients and allow preventative actions. While many models can predict the occurrence of seizures from features of the EEG, few models incorporate changes in features over…

Neurons and Cognition · Quantitative Biology 2023-09-19 Daniel E. Payne , Jordan D. Chambers , Anthony Burkitt , Mark J. Cook , Levin Kuhlman , Dean R. Freestone , David B. Grayden