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Parameter-efficient fine-tuning has demonstrated promising results across various visual adaptation tasks, such as classification and segmentation. Typically, prompt tuning techniques have harnessed knowledge from a single pre-trained…

Computer Vision and Pattern Recognition · Computer Science 2026-02-27 Shentong Mo , Xufang Luo , Dongsheng Li

Graph Neural Networks (GNNs) face a fundamental adaptability challenge: their fixed message-passing architectures struggle with the immense diversity of real-world graphs, where optimal computational strategies vary by local structure and…

Machine Learning · Computer Science 2025-10-27 Yunlong Chu , Minglai Shao , Zengyi Wo , Bing Hao , Yuhang Liu , Ruijie Wang , Jianxin Li

Advances in natural language processing and large language models have sparked growing interest in modeling DNA, often referred to as the "language of life". However, DNA modeling poses unique challenges. First, it requires the ability to…

While RNA has recently been recognized as an interesting small-molecule drug target, many challenges remain to be addressed before we take full advantage of it. This emphasizes the necessity to improve our understanding of its structures…

Biomolecules · Quantitative Biology 2025-07-15 Rafael Josip Penić , Tin Vlašić , Roland G. Huber , Yue Wan , Mile Šikić

Large Language Models (LLMs) are increasingly employed as AI tutors due to their scalability and potential for personalized instruction. However, off-the-shelf LLMs often underperform in educational settings: they frequently reveal answers…

Computation and Language · Computer Science 2025-08-13 Shuzhou Yuan , William LaCroix , Hardik Ghoshal , Ercong Nie , Michael Färber

Molecular property prediction is essential for applications such as drug discovery and toxicity assessment. While Graph Neural Networks (GNNs) have shown promising results by modeling molecules as molecular graphs, their reliance on…

Machine Learning · Computer Science 2025-04-09 Tianyi Jiang , Zeyu Wang , Shanqing Yu , Qi Xuan

While Low-Rank Adaptation (LoRA) enables parameter-efficient fine-tuning for Large Language Models (LLMs), its performance often falls short of Full Fine-Tuning (Full FT). Current methods optimize LoRA by initializing with static singular…

Computation and Language · Computer Science 2026-03-04 Chenghao Fan , Zhenyi Lu , Sichen Liu , Chengfeng Gu , Xiaoye Qu , Wei Wei , Yu Cheng

By increasing model parameters but activating them sparsely when performing a task, the use of Mixture-of-Experts (MoE) architecture significantly improves the performance of Large Language Models (LLMs) without increasing the inference…

Computation and Language · Computer Science 2025-06-10 Zeliang Zhang , Xiaodong Liu , Hao Cheng , Chenliang Xu , Jianfeng Gao

Sparse Mixture of Experts (MoE) large language models (LLMs) are gradually becoming the mainstream approach for ultra-large-scale models. Existing optimization efforts for MoE models have focused primarily on coarse-grained MoE…

Computation and Language · Computer Science 2025-05-07 Haoqi Yang , Luohe Shi , Qiwei Li , Zuchao Li , Ping Wang , Bo Du , Mengjia Shen , Hai Zhao

We present Uni-MoE 2.0 from the Lychee family. As a fully open-source omnimodal large model (OLM), it substantially advances Lychee's Uni-MoE series in language-centric multimodal understanding, reasoning, and generating. Based on the dense…

Computation and Language · Computer Science 2025-11-25 Yunxin Li , Xinyu Chen , Shenyuan Jiang , Haoyuan Shi , Zhenyu Liu , Xuanyu Zhang , Nanhao Deng , Zhenran Xu , Yicheng Ma , Meishan Zhang , Baotian Hu , Min Zhang

Given the recent impressive accomplishments of language models (LMs) for code generation, we explore the use of LMs as adaptive mutation and crossover operators for an evolutionary neural architecture search (NAS) algorithm. While NAS still…

Neural and Evolutionary Computing · Computer Science 2023-11-17 Angelica Chen , David M. Dohan , David R. So

Mixture-of-Experts (MoE) architectures have emerged as a promising paradigm for scaling large language models (LLMs) with sparse activation of task-specific experts. Despite their computational efficiency during inference, the massive…

Computation and Language · Computer Science 2025-04-11 Hongcheng Guo , Juntao Yao , Boyang Wang , Junjia Du , Shaosheng Cao , Donglin Di , Shun Zhang , Zhoujun Li

The scaling of large language models (LLMs) has revolutionized their capabilities in various tasks, yet this growth must be matched with efficient computational strategies. The Mixture-of-Experts (MoE) architecture stands out for its…

Computation and Language · Computer Science 2025-03-20 Zihan Qiu , Zeyu Huang , Shuang Cheng , Yizhi Zhou , Zili Wang , Ivan Titov , Jie Fu

Large Language Models (LLMs) have the potential to revolutionize data analytics by simplifying tasks such as data discovery and SQL query synthesis through natural language interactions. This work serves as a pivotal first step toward the…

Aligning pretrained audio encoders and Large Language Models (LLMs) offers a promising, parameter-efficient path to building powerful multimodal agents. However, existing methods often require costly full-model finetuning or rely on static…

Sound · Computer Science 2025-10-16 Ruitao Feng , Bixi Zhang , Sheng Liang , Zheng Yuan

The rapid evolution of artificial intelligence in drug discovery encounters challenges with generalization and extensive training, yet Large Language Models (LLMs) offer promise in reshaping interactions with complex molecular data. Our…

Biomolecules · Quantitative Biology 2024-12-20 He Cao , Zijing Liu , Xingyu Lu , Yuan Yao , Yu Li

Adapting medical Large Language Models to local languages can reduce barriers to accessing healthcare services, but data scarcity remains a significant challenge, particularly for low-resource languages. To address this, we first construct…

Computation and Language · Computer Science 2025-02-11 Guorui Zheng , Xidong Wang , Juhao Liang , Nuo Chen , Yuping Zheng , Benyou Wang

LoRA-MoE has emerged as an effective paradigm for parameter-efficient fine-tuning, combining the low training cost of LoRA with the increased adaptation capacity of Mixture-of-Experts (MoE). However, existing LoRA-MoE frameworks typically…

Machine Learning · Computer Science 2026-04-30 Weihang Li , Jianchun Liu , Hongli Xu

Graph neural networks excel at graph representation learning but struggle with heterophilous data and long-range dependencies. And graph transformers address these issues through self-attention, yet face scalability and noise challenges on…

Machine Learning · Computer Science 2025-02-13 Xuanze Chen , Jiajun Zhou , Shanqing Yu , Qi Xuan

We present a unified Vision-Language pretrained Model (VLMo) that jointly learns a dual encoder and a fusion encoder with a modular Transformer network. Specifically, we introduce Mixture-of-Modality-Experts (MoME) Transformer, where each…

Computer Vision and Pattern Recognition · Computer Science 2022-05-30 Hangbo Bao , Wenhui Wang , Li Dong , Qiang Liu , Owais Khan Mohammed , Kriti Aggarwal , Subhojit Som , Furu Wei