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Fetal Magnetic Resonance Imaging (MRI) is used in prenatal diagnosis and to assess early brain development. Accurate segmentation of the different brain tissues is a vital step in several brain analysis tasks, such as cortical surface…

Image and Video Processing · Electrical Eng. & Systems 2022-05-18 Liu Li , Qiang Ma , Matthew Sinclair , Antonios Makropoulos , Joseph Hajnal , A. David Edwards , Bernhard Kainz , Daniel Rueckert , Amir Alansary

Characterizing in-utero brain development is essential for understanding typical and atypical neurodevelopment. Building on prior spatiotemporal fetal brain MRI atlases, we present the CRL-2025 fetal brain atlas, a spatiotemporal (4D) atlas…

Longitudinal fetal brain atlas is a powerful tool for understanding and characterizing the complex process of fetus brain development. Existing fetus brain atlases are typically constructed by averaged brain images on discrete time points…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Lixuan Chen , Jiangjie Wu , Qing Wu , Hongjiang Wei , Yuyao Zhang

It is critical to quantitatively analyse the developing human fetal brain in order to fully understand neurodevelopment in both normal fetuses and those with congenital disorders. To facilitate this analysis, automatic multi-tissue fetal…

Automatic fetal brain tissue segmentation can enhance the quantitative assessment of brain development at this critical stage. Deep learning methods represent the state of the art in medical image segmentation and have also achieved…

Image and Video Processing · Electrical Eng. & Systems 2023-01-05 Davood Karimi , Caitlin K. Rollins , Clemente Velasco-Annis , Abdelhakim Ouaalam , Ali Gholipour

This paper presents FeTal-SAM, a novel adaptation of the Segment Anything Model (SAM) tailored for fetal brain MRI segmentation. Traditional deep learning methods often require large annotated datasets for a fixed set of labels, making them…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Qi Zeng , Weide Liu , Bo Li , Ryne Didier , P. Ellen Grant , Davood Karimi

Accurate automatic tissue segmentation in fetal brain MRI is a crucial step in clinical diagnosis but remains challenging, particularly due to the dynamically changing anatomy and tissue contrast during fetal development. Existing…

Image and Video Processing · Electrical Eng. & Systems 2025-03-12 Haoan Xu , Tianshu Zheng , Xinyi Xu , Yao Shen , Jiwei Sun , Cong Sun , Guangbin Wang , Zhaopeng Cui , Dan Wu

Fetal brain segmentation is an important first step for slice-level motion correction and slice-to-volume reconstruction in fetal MRI. Fast and accurate segmentation of the fetal brain on fetal MRI is required to achieve real-time fetal…

Image and Video Processing · Electrical Eng. & Systems 2022-05-05 Razieh Faghihpirayesh , Davood Karimi , Deniz Erdogmus , Ali Gholipour

Segmentation and spatial alignment of ultrasound (US) imaging data acquired in the in first trimester are crucial for monitoring human embryonic growth and development throughout this crucial period of life. Current approaches are either…

Image and Video Processing · Electrical Eng. & Systems 2023-08-29 W. A. P. Bastiaansen , M. Rousian , R. P. M. Steegers-Theunissen , W. J. Niessen , A. H. J. Koning , S. Klein

We propose an unsupervised deep learning method for atlas based registration to achieve segmentation and spatial alignment of the embryonic brain in a single framework. Our approach consists of two sequential networks with a specifically…

Image and Video Processing · Electrical Eng. & Systems 2020-05-14 Wietske A. P. Bastiaansen , Melek Rousian , Régine P. M. Steegers-Theunissen , Wiro J. Niessen , Anton Koning , Stefan Klein

Brain segmentation is a fundamental first step in neuroimage analysis. In the case of fetal MRI, it is particularly challenging and important due to the arbitrary orientation of the fetus, organs that surround the fetal head, and…

MR images of fetuses allow clinicians to detect brain abnormalities in an early stage of development. The cornerstone of volumetric and morphologic analysis in fetal MRI is segmentation of the fetal brain into different tissue classes.…

Image and Video Processing · Electrical Eng. & Systems 2019-06-12 N. Khalili , N. Lessmann , E. Turk , N. Claessens , R. de Heus , T. Kolk , M. A. Viergever , M. J. N. L. Benders , I. Isgum

Early brain development is crucial for lifelong neurodevelopmental health. However, current clinical practice offers limited knowledge of normal embryonic brain anatomy on ultrasound, despite the brain undergoing rapid changes within the…

The automatic segmentation of perinatal brain structures in magnetic resonance imaging (MRI) is of utmost importance for the study of brain growth and related complications. While different methods exist for adult and pediatric MRI data,…

We introduce a conditional implicit neural atlas (CINA) for spatio-temporal atlas generation from Magnetic Resonance Images (MRI) of the neurotypical and pathological fetal brain, that is fully independent of affine or non-rigid…

We present a method for fast biomedical image atlas construction using neural fields. Atlases are key to biomedical image analysis tasks, yet conventional and deep network estimation methods remain time-intensive. In this preliminary work,…

Image and Video Processing · Electrical Eng. & Systems 2023-11-15 Zeen Chi , Zhongxiao Cong , Clinton J. Wang , Yingcheng Liu , Esra Abaci Turk , P. Ellen Grant , S. Mazdak Abulnaga , Polina Golland , Neel Dey

Fetal cortical plate segmentation is essential in quantitative analysis of fetal brain maturation and cortical folding. Manual segmentation of the cortical plate, or manual refinement of automatic segmentations is tedious and…

Computer Vision and Pattern Recognition · Computer Science 2021-04-05 Haoran Dou , Davood Karimi , Caitlin K. Rollins , Cynthia M. Ortinau , Lana Vasung , Clemente Velasco-Annis , Abdelhakim Ouaalam , Xin Yang , Dong Ni , Ali Gholipour

Fetal brain imaging is a cornerstone of prenatal screening and early diagnosis of congenital anomalies. Knowledge of fetal gestational age is the key to the accurate assessment of brain development. This study develops an attention-based…

Computer Vision and Pattern Recognition · Computer Science 2018-12-19 Liyue Shen , Katie Shpanskaya , Edward Lee , Emily McKenna , Maryam Maleki , Quin Lu , Safwan Halabi , John Pauly , Kristen Yeom

Magnetic resonance imaging (MRI) has played a crucial role in fetal neurodevelopmental research. Structural annotations of MR images are an important step for quantitative analysis of the developing human brain, with Deep Learning providing…

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