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In this paper we propose a solution to the need for a fast particle transport algorithm in Online Adaptive Proton Therapy capable of cheaply, but accurately computing the changes in patient dose metrics as a result of changes in the system…

Medical Physics · Physics 2022-08-26 Tiberiu Burlacu , Danny Lathouwers , Zoltán Perkó

Transport maps have become a popular mechanic to express complicated probability densities using sample propagation through an optimized push-forward. Beside their broad applicability and well-known success, transport maps suffer from…

Numerical Analysis · Mathematics 2020-08-11 Martin Eigel , Robert Gruhlke , Manuel Marschall

Currently, existing tensor recovery methods fail to recognize the impact of tensor scale variations on their structural characteristics. Furthermore, existing studies face prohibitive computational costs when dealing with large-scale…

Machine Learning · Computer Science 2025-07-09 Wenjin Qin , Hailin Wang , Jingyao Hou , Jianjun Wang

Effectively integrating molecular graph structures with Large Language Models (LLMs) is a key challenge in drug discovery. Most existing multi-modal alignment methods typically process these structures by fine-tuning the LLM or adding a…

Machine Learning · Computer Science 2025-10-15 Tao Yin , Xiaohong Zhang , Jiacheng Zhang , Li Huang , Zhibin Zhang , Yuansong Zeng , Jin Xie , Meng Yan

Weighted low-rank approximation (WLRA), a dimensionality reduction technique for data analysis, has been successfully used in several applications, such as in collaborative filtering to design recommender systems or in computer vision to…

Optimization and Control · Mathematics 2012-08-13 Nicolas Gillis , François Glineur

An efficient technique based on low-rank separated approximations is proposed for computation of three-dimensional integrals arising in the energy deposition model that describes ion-atomic collisions. Direct tensor-product quadrature…

Computational Physics · Physics 2015-11-17 M. S. Litsarev , I. V. Oseledets

In this paper, we propose SubLoRA, a rank determination method for Low-Rank Adaptation (LoRA) based on submodular function maximization. In contrast to prior approaches, such as AdaLoRA, that rely on first-order (linearized) approximations…

Machine Learning · Computer Science 2025-07-03 Yihang Gao , Vincent Y. F. Tan

A matrix algorithm runs at {\em sublinear cost} if it uses much fewer memory cells and arithmetic operations than the input matrix has entries. Such algorithms are indispensable for Big Data Mining and Analysis. Quite typically in that area…

Numerical Analysis · Mathematics 2021-04-02 Qi Luan , Victor Y. Pan , John Svadlenka

We consider dynamical low-rank approximations to parabolic problems on higher-order tensor manifolds in Hilbert spaces. In addition to existence of solutions and their stability with respect to perturbations to the problem data, we show…

Numerical Analysis · Mathematics 2025-05-19 Markus Bachmayr , Henrik Eisenmann , André Uschmajew

The dynamical low-rank approximation of time-dependent matrices is a low-rank factorization updating technique. It leads to differential equations for factors of the matrices, which need to be solved numerically. We propose and analyze a…

Numerical Analysis · Mathematics 2013-01-09 Christian Lubich , Ivan Oseledets

Low Rank Approximation (LRA) of a matrix is a hot research subject, fundamental for Matrix and Tensor Computations and Big Data Mining and Analysis. Computations with low rank matrices can be performed at sublinear cost -- by using much…

Numerical Analysis · Mathematics 2025-08-11 Qi Luan , Victor Y. Pan , John Svadlenka , Liang Zhao

A model for beam customization with collimators and a range-compensating filter based on the phase-space theory for beam transport is presented for dose distribution calculation in treatment planning of radiotherapy with protons and heavier…

Medical Physics · Physics 2008-05-27 Nobuyuki Kanematsu , Shunsuke Yonai , Azusa Ishizaki , Masami Torikoshi

Kinetic equations are difficult to solve numerically due to their high dimensionality. A promising approach for reducing computational cost is the dynamical low-rank algorithm, which decouples the dimensions of the phase space by proposing…

Numerical Analysis · Mathematics 2022-04-26 Jack Coughlin , Jingwei Hu

Purpose: Various dose calculation algorithms are available for radiation therapy for cancer patients. However, these algorithms are faced with the tradeoff between efficiency and accuracy. The fast algorithms are generally less accurate,…

Medical Physics · Physics 2020-07-01 Yixun Xing , Dan Nguyen , Weiguo Lu , Ming Yang , Steve Jiang

One of the most effective orthogonal moments, discrete Racah polynomials (DRPs) and their moments are used in many disciplines of sciences, including image processing, and computer vision. Moments are the projections of a signal on the…

Numerical Analysis · Mathematics 2023-02-02 Basheera M. Mahmmod , Sadiq H. Abdulhussain , Tomáš Suk

We develop two new sets of stable, rank-adaptive Dynamically Orthogonal Runge-Kutta (DORK) schemes that capture the high-order curvature of the nonlinear low-rank manifold. The DORK schemes asymptotically approximate the truncated singular…

Numerical Analysis · Mathematics 2023-08-08 Aaron Charous , Pierre F. J. Lermusiaux

This work addresses computing techniques for dose calculations in treatment planning with proton and ion beams, based on an efficient kernel-convolution method referred to as grid-dose spreading (GDS) and accurate heterogeneity-correction…

Medical Physics · Physics 2012-01-11 Nobuyuki Kanematsu

Low-rank methods have emerged as a promising strategy for reducing the memory footprint and computational cost of discrete-ordinates discretizations of the radiative transfer equation (RTE). However, most existing rank-adaptive approaches…

Numerical Analysis · Mathematics 2026-04-14 Wei Guo , Zhichao Peng

Low-rank modeling has a lot of important applications in machine learning, computer vision and social network analysis. While the matrix rank is often approximated by the convex nuclear norm, the use of nonconvex low-rank regularizers has…

Numerical Analysis · Computer Science 2016-05-02 Quanming Yao , James T. Kwok , Wenliang Zhong

In intensity-modulated radiation therapy, optimal intensity distributions of incoming beams are decomposed into linear combinations of leaf openings of a multileaf collimator (segments). In order to avoid inefficient dose delivery, the…

Medical Physics · Physics 2010-09-29 Antje Kiesel , Tobias Gauer