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Large Language Models (LLMs) are increasingly applied in healthcare, yet ensuring their ethical integrity and safety compliance remains a major barrier to clinical deployment. This work introduces a multi-agent refinement framework designed…

Automating radiology report generation poses a dual challenge: building clinically reliable systems and designing rigorous evaluation protocols. We introduce a multi-agent reinforcement learning framework that serves as both a benchmark and…

Artificial Intelligence · Computer Science 2025-09-23 Ahmed T. Elboardy , Ghada Khoriba , Essam A. Rashed

Recent advances in large language models (LLMs) have shown strong reasoning capabilities through large-scale pretraining and post-training reinforcement learning, demonstrated by DeepSeek-R1. However, current post-training methods, such as…

Artificial Intelligence · Computer Science 2025-12-04 Boyang Gu , Hongjian Zhou , Bradley Max Segal , Jinge Wu , Zeyu Cao , Hantao Zhong , Lei Clifton , Fenglin Liu , David A. Clifton

Large language models (LLMs) have demonstrated strong performance on medical benchmarks, including question answering and diagnosis. To enable their use in clinical settings, LLMs are typically further adapted through continued pretraining…

The potential of Multimodal Large Language Models (MLLMs) in domain of medical imaging raise the demands of systematic and rigorous evaluation frameworks that are aligned with the real-world medical imaging practice. Existing practices that…

Computation and Language · Computer Science 2026-04-16 Zhijie Bao , Fangke Chen , Licheng Bao , Chenhui Zhang , Wei Chen , Jiajie Peng , Zhongyu Wei

Fueled by breakthrough technology developments, the biological, biomedical, and behavioral sciences are now collecting more data than ever before. There is a critical need for time- and cost-efficient strategies to analyze and interpret…

State-of-the-art medical multi-modal LLMs (med-MLLMs), such as LLaVA-Med and BioMedGPT, primarily depend on scaling model size and data volume, with training driven largely by autoregressive objectives. However, we reveal that this approach…

Biomedical language understanding benchmarks are the driving forces for artificial intelligence applications with large language model (LLM) back-ends. However, most current benchmarks: (a) are limited to English which makes it challenging…

Computation and Language · Computer Science 2023-10-24 Wei Zhu , Xiaoling Wang , Huanran Zheng , Mosha Chen , Buzhou Tang

Vision-Language Models (VLMs) can generate convincing clinical narratives, yet frequently struggle to visually ground their statements. We posit this limitation arises from the scarcity of high-quality, large-scale clinical…

Computer Vision and Pattern Recognition · Computer Science 2026-01-13 Mengmeng Zhang , Xiaoping Wu , Hao Luo , Fan Wang , Yisheng Lv

Clinical decision-making routinely demands reasoning over heterogeneous data, yet existing multimodal language models (MLLMs) remain largely vision-centric and fail to generalize across clinical specialties. To bridge this gap, we introduce…

Machine Learning · Computer Science 2025-10-23 Wei Dai , Peilin Chen , Chanakya Ekbote , Paul Pu Liang

Large language models have achieved strong performance on medical reasoning benchmarks, yet their deployment in clinical settings demands rigorous verification to ensure factual accuracy. While reward models offer a scalable approach for…

Artificial Intelligence · Computer Science 2026-01-29 Hang Zhang , Ruheng Wang , Yuelyu Ji , Mingu Kwak , Xizhi Wu , Chenyu Li , Li Zhang , Wenqi Shi , Yifan Peng , Yanshan Wang

Artificial intelligence has demonstrated significant potential in clinical decision-making; however, developing models capable of adapting to diverse real-world scenarios and performing complex diagnostic reasoning remains a major…

Computer Vision and Pattern Recognition · Computer Science 2025-08-18 Ronghao Xu , Zhen Huang , Yangbo Wei , Xiaoqian Zhou , Zikang Xu , Ting Liu , Zihang Jiang , S. Kevin Zhou

Recently, large language model (LLM) based artificial intelligence (AI) systems have demonstrated remarkable capabilities in natural language understanding and generation. However, these models face a significant challenge when it comes to…

MLLMs have been successfully applied to multimodal embedding tasks, yet their generative reasoning capabilities remain underutilized. Directly incorporating chain-of-thought reasoning into embedding learning introduces two fundamental…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Yuchi Wang , Haiyang Yu , Weikang Bian , Jiefeng Long , Xiao Liang , Chao Feng , Hongsheng Li

This study analyzes the performance of domain-specific Large Language Models (LLMs) for the medical field by integrating Retrieval-Augmented Generation (RAG) systems within a federated learning framework. Leveraging the inherent advantages…

Computation and Language · Computer Science 2025-01-09 Jincheol Jung , Hongju Jeong , Eui-Nam Huh

Large language models (LLMs) have shown substantial progress in natural language understanding and generation, proving valuable especially in the medical field. Despite advancements, challenges persist due to the complexity and diversity…

Computation and Language · Computer Science 2024-10-18 Yusheng Liao , Shuyang Jiang , Zhe Chen , Yanfeng Wang , Yu Wang

Task arithmetic is a powerful technique for transferring skills between Large Language Models (LLMs), but it often suffers from negative interference when models have diverged during training. We address this limitation by first aligning…

Computation and Language · Computer Science 2025-11-17 Stefan Horoi , Sangwoo Cho , Supriyo Chakraborty , Shi-Xiong Zhang , Sambit Sahu , Guy Wolf , Genta Indra Winata

Evaluating medical AI systems using expert clinician panels is costly and slow, motivating the use of large language models (LLMs) as alternative adjudicators. Here, we evaluate an LLM jury composed of three frontier AI models scoring 3333…

Recent advances in large language models (LLMs) have made significant progress across multiple biomedical tasks, including biomedical question answering, lay-language summarization of the biomedical literature, and clinical note…

Information Retrieval · Computer Science 2026-03-24 Deepak Gupta , Dina Demner-Fushman , William Hersh , Steven Bedrick , Kirk Roberts

In numerous reinforcement learning (RL) problems involving safety-critical systems, a key challenge lies in balancing multiple objectives while simultaneously meeting all stringent safety constraints. To tackle this issue, we propose a…

Artificial Intelligence · Computer Science 2024-05-28 Shangding Gu , Bilgehan Sel , Yuhao Ding , Lu Wang , Qingwei Lin , Alois Knoll , Ming Jin