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Poly(N-isopropylacrylamide) (PNIPAM) is a temperature-responsive polymer that undergoes large volumetric deformations through a transition from a swollen to a collapsed state at the volume phase transition temperature (VPTT). Locally, these…

Soft Condensed Matter · Physics 2025-12-23 Noy Cohen

Thermoresponsive hydrogels have been studied intensively for creating smart drug carriers and controlled drug delivery. Understanding the drug release kinetics and corresponding transport mechanisms of nanoparticles (NPs) in a…

Soft Condensed Matter · Physics 2020-05-12 Yi Wang , Zhen Li , Jie Ouyang , George Em Karniadakis

Multiblock copolymer chains in implicit nonselective solvents are studied by Monte Carlo method which employs a parallel tempering algorithm. Chains consisting of 120 $A$ and 120 $B$ monomers, arranged in three distinct microarchitectures:…

Soft Condensed Matter · Physics 2014-10-20 Krzysztof Lewandowski , Michal Banaszak

Microgels are colloidal-scale particles individually made of crosslinked polymer networks that can swell and deswell in response to external stimuli, such as changes to temperature or pH. Despite a large amount of experimental activities on…

Soft Condensed Matter · Physics 2019-02-08 Nicoletta Gnan , Lorenzo Rovigatti , Maxime Bergman , Emanuela Zaccarelli

Microgels are elastic and deformable particles with a hybrid nature between that of polymers and colloids and unconventional behaviours with respect to hard colloids. We investigated the dynamics of a soft microgel made of interpenetrated…

Microgel particles composed of Interpenetrated Polymer Networks (IPN) of poly(N-isopropylacrylamide) (PNIPAM) and poly(acrylic acid) (PAAc) dispersed in water have been investigated through dynamic light scattering. The study of the…

Thermo-responsive microgel particles can exhibit a drastic volume shrinkage upon increasing the solvent temperature. Recently we found that the spreading of poly(N-isopropylacrylamide)(PNiPAm) microgels at a liquid interface under the…

Microgel suspensions of Interpenetrated Polymer Network (IPN) of PNIPAM and PAAc in D$_2$O, have been investigated through dynamic light scattering as a function of temperature, pH and concentration across the Volume Phase Transition (VPT).…

Microstructurally arrested matter, from molecular glasses to soft glassy materials, can retain a memory of their thermal or mechanical (shear) histories. Their history-dependent and nonlinear microstructural recoveries have been studied…

Soft Condensed Matter · Physics 2025-11-05 Sonali Vasant Kawale , Yogesh M Joshi , Ranjini Bandyopadhyay

PNIPAm microgels synthesized via free radical polymerization (FRP) are often considered as neutral colloids in aqueous media, although it is well known, since the pioneering work of Pelton and coworkers [Langmuir 1989, 5, 816-818], that the…

Soft Condensed Matter · Physics 2021-04-06 Simona Sennato , Edouard Chauveau , Stefano Casciardi , Federico Bordi , Domenico Truzzolillo

Ionic microgel particles are intriguing systems in which the properties of thermo-responsive polymeric colloids are enriched by the presence of charged groups. In order to rationalize their properties and predict the behaviour of microgel…

Soft Condensed Matter · Physics 2021-01-28 G. Del Monte , F. Camerin , A. Ninarello , N. Gnan , L. Rovigatti , E. Zaccarelli

Stimuli-responsive lyogels are known for their ability to undergo significant macroscopic changes when exposed to external stimuli. While thermo-responsive gels, such as poly N isopropylacrylamide (pNIPAM), have been extensively studied…

The self-assembly of copolymeric vesicles and micelles in micromixers is studied by External Potential Dynamics (EPD) simulations -- a dynamic density functional approach that explicitly accounts for the polymer architecture both at the…

Soft Condensed Matter · Physics 2018-04-10 Simon Kessler , Klaus Drese , Friederike Schmid

The formation of smart emulsions or foams whose stability can be controlled on-demand by switching external parameters is of great interest for basic research and applications. An emerging group of smart stabilizers are microgels, which are…

Soft Condensed Matter · Physics 2020-12-09 Steffen Bochenek , Andrea Scotti , Walter Richtering

We employ small-angle X-ray and dynamic light scattering to investigate the microscopic structure and dynamics of dense suspensions of ultra-low crosslinked (ULC) poly(N-isopropylacrylamide) (PNIPAM) microgels. By probing the supercooled…

Soft Condensed Matter · Physics 2026-01-01 A. Martinelli , R. Elancheliyan , A. Scotti , A. V. Petrunin , D. Truzzolillo , L. Cipelletti

A central quantity in the design of functional hydrogels used as nanocarrier systems, for instance for drug delivery or adaptive nanocatalysis, is the partition ratio, which quantifies the uptake of a molecular substance by the polymer…

Soft Condensed Matter · Physics 2019-01-08 Matej Kanduc , Won Kyu Kim , Rafael Roa , Joachim Dzubiella

Hollow microgels, consisting of a pNIPAM polymer network with a central cavity, have significant potential due to their tunable softness and encapsulation capabilities. Using molecular dynamics simulations, we thoroughly characterise the…

Soft Condensed Matter · Physics 2025-04-28 Leah Rank , Emanuela Zaccarelli

We study the swelling and shrinking behavior of core-shell microgels adsorbed on silicon wafers. In these systems, the core is made of cross-linked poly(N isopropylmethacrylamide) and the shell consists of cross linked poly(N-n…

Soft Condensed Matter · Physics 2018-11-22 Marian Cors , Oliver Wrede , Anne-Caroline Genix , Dario Anselmetti , Julian Oberdisse , Thomas Hellweg

Interpenetrated Polymer Network (IPN) microgels of PNIPAM and PAAc have been investigated and the experimental data have been compared with theoretical models from the Flory-Rehner theory. We confirm that the swelling behavior of PNIPAM…

Soft Condensed Matter · Physics 2019-06-24 Valentina Nigro , Roberta Angelini , Monica Bertoldo , Barbara Ruzicka

By means of atomistic molecular dynamics simulations we investigate the behaviour of poly(N-isopropylacrylamide), PNIPAM, in water at temperatures below and above the lower critical solution temperature (LCST), including the undercooled…

Soft Condensed Matter · Physics 2019-02-11 L. Tavagnacco , E. Zaccarelli , E. Chiessi