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The connection and eventual integration of High-Performance Computing (HPC) with Quantum Computing (QC) represents a transformative advancement in computational technology, promising significant enhancements in solving complex, previously…

We define some of the programming and system-level challenges facing the application of quantum processing to high-performance computing. Alongside barriers to physical integration, prominent differences in the execution of quantum and…

Quantum Physics · Physics 2017-12-06 Keith A. Britt , Fahd A. Mohiyaddin , Travis S. Humble

The purpose of this paper is to explore the applications of quantum computing to energy systems optimization problems and discuss some of the challenges faced by quantum computers with techniques to overcome them. The basic concepts…

Quantum Physics · Physics 2020-03-03 Akshay Ajagekar , Fengqi You

Rapid advancements in cloud based platforms providing access to quantum computing capabilities have opened up several challenges for efficient usage of these highly delicate and costly devices. Although most of the current systems use a…

Quantum Physics · Physics 2026-05-19 Abhishek Sawaika , Udaya Parampalli , Rajkumar Buyya

Robust execution environments are important for addressing key challenges in quantum computing, such as application development, portability, and reproducibility, and help unlock the development of modular quantum programs, driving forward…

Quantum Physics · Physics 2025-09-26 Aleksander Wennersteen , Matthieu Moreau , Aurelien Nober , Mourad Beji

High Performance Computing (HPC), Artificial Intelligence (AI)/Machine Learning (ML), and Quantum Computing (QC) and communications offer immense opportunities for innovation and impact on society. Researchers in these areas depend on…

Computers and Society · Computer Science 2020-12-18 William Gropp , Sujata Banerjee , Ian Foster

Programming for today's quantum computers is making significant strides toward modern workflows compatible with high performance computing (HPC), but fundamental challenges still remain in the integration of these vastly different…

Quantum computers have demonstrated utility in simulating quantum systems beyond brute-force classical approaches. As the community builds on these demonstrations to explore using quantum computing for applied research, algorithms and…

The quest for real-time dynamic optimization solutions in the process industry represents a formidable computational challenge, particularly within the realm of applications like model-predictive control, where rapid and reliable…

Optimization and Control · Mathematics 2024-04-29 Dennis Michael Nenno , Adrian Caspari

Recently, increased computational power and data availability, as well as algorithmic advances, have led machine learning techniques to impressive results in regression, classification, data-generation and reinforcement learning tasks.…

The current state of quantum computing is commonly described as the Noisy Intermediate-Scale Quantum era. Available computers contain a few dozens of qubits and can perform a few dozens of operations before the inevitable noise erases all…

Quantum Physics · Physics 2024-09-25 Ijaz Ahamed Mohammad , Matej Pivoluska , Martin Plesch

Quantum computing promises to solve difficult optimization problems in chemistry, physics and mathematics more efficiently than classical computers, but requires fault-tolerant quantum computers with millions of qubits. To overcome errors…

Databases · Computer Science 2021-07-23 Tobias Fankhauser , Marc E. Solèr , Rudolf M. Füchslin , Kurt Stockinger

Quantum computing has shown significant potential to address complex optimization problems; however, its application remains confined to specific problems at limited scales. Spatial regionalization remains largely unexplored in quantum…

Emerging Technologies · Computer Science 2025-07-29 Yunhan Chang , Amr Magdy , Federico M. Spedalieri , Ibrahim Sabek

One of the open challenges in quantum computing is to find meaningful and practical methods to leverage quantum computation to accelerate classical machine learning workflows. A ubiquitous problem in machine learning workflows is sampling…

Quantum Physics · Physics 2024-08-08 Owen Lockwood , Peter Weiss , Filip Aronshtein , Guillaume Verdon

Quantum computing (QC) offers a new computing paradigm that has the potential to provide significant speedups over classical computing. Each additional qubit doubles the size of the computational state space available to a quantum…

Quantum Physics · Physics 2022-05-13 Wei Tang , Margaret Martonosi

Despite numerous advances in the field and a seemingly ever-increasing amount of investment, we are still some years away from seeing a production quantum computer in action. However, it is possible to make some educated guesses about the…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-06-22 James H. Davenport , Jessica R. Jones , Matthew Thomason

Machine learning techniques have achieved impressive results in recent years and the possibility of harnessing the power of quantum physics opens new promising avenues to speed up classical learning methods. Rather than viewing classical…

Quantum Physics · Physics 2025-01-10 Johannes Nokkala , Gian Luca Giorgi , Roberta Zambrini

Quantum computing is presently undergoing rapid development to achieve a significant speedup promised in certain applications. Nonetheless, scaling quantum computers remains a formidable engineering challenge, prompting exploration of…

Exploiting quantum computing at the mobile edge holds immense potential for facilitating large-scale network design, processing multimodal data, optimizing resource management, and enhancing network security. In this paper, we propose a…

Networking and Internet Architecture · Computer Science 2025-04-14 Minrui Xu , Dusit Niyato , Jiawen Kang , Zehui Xiong , Mingzhe Chen , Dong In Kim , Xuemin , Shen

The practical application of quantum technologies to chemical problems faces significant challenges, particularly in the treatment of realistic basis sets and the accurate inclusion of electron correlation effects. A direct approach to…