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In this paper, we first propose a diffusive pathogen infection model with general incidence rate which incorporates cell-to-cell transmission. By applying the theory of monotone dynamical systems, we prove that the model admits the global…

Analysis of PDEs · Mathematics 2026-02-24 Shohel Ahmed

A complex contagion is an infectious process in which individuals may require multiple transmissions before changing state. These are used to model behaviors if an individual only adopts a particular behavior after perceiving a consensus…

Physics and Society · Physics 2015-06-29 Joel C. Miller

Recent statistics of malaria shows that over 200 million cases and estimated deaths of nearly half a million occur globally. Africa alone accounts for almost 90% of the cases. Several studies have been conducted to understand the disease…

Populations and Evolution · Quantitative Biology 2020-04-15 Babagana Modu , Nereida Polovina , Savas Konur

Disease and pest control largely rely on pesticides use and progress still remains to be made towards more sustainable practices. Pest Monitoring Networks (PMNs) can provide useful information for improving crop protection by restricting…

Populations and Evolution · Quantitative Biology 2020-02-05 Marie-Josée Cros , Jean-Noël Aubertot , Sabrina Gaba , Xavier Reboud , Régis Sabbadin , Nathalie Peyrard

Understanding dynamics of an infectious disease helps in designing appropriate strategies for containing its spread in a population. Recent mathematical models are aimed at studying dynamics of some specific types of infectious diseases. In…

Dynamical Systems · Mathematics 2015-02-05 P. Raja Sekhara Rao , M. Naresh Kumar

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

In this paper, the steeped-transmission shaft design problem is proposed for weight optimization. The bio-inspired search-based Snail Homing and Mating Search (SHMS) algorithm is utilized to solve the problem. It is inspired by the social…

Neural and Evolutionary Computing · Computer Science 2025-09-18 Kaustav Saha , Ishaan R Kale , Vivek Patel , Anand J Kulkarni , Puskaraj D Sonawwanay

Malaria, childhood acute respiratory infection, and child undernutrition together account for over two million deaths annually in children under five, with the burden concentrated in low and middle-income countries where climate variability…

Applications · Statistics 2026-05-13 Usman Nazir , I-Han Cheng , Sara Khalid

We use a stochastic Markovian dynamics approach to describe the spreading of vector-transmitted diseases, like dengue, and the threshold of the disease. The coexistence space is composed by two structures representing the human and mosquito…

Populations and Evolution · Quantitative Biology 2013-01-01 David R. Souza , Tânia Tomé , Suani T. R. Pinho , Florisneide R. Barreto , Mário J. de Oliveira

We investigate a model for spatial epidemics explicitly taking into account bi-directional movements between base and destination locations on individual mobility networks. We provide a systematic analysis of generic dynamical features of…

Physics and Society · Physics 2012-03-07 Vitaly Belik , Theo Geisel , Dirk Brockmann

Modeling and simulation of disease spreading in pedestrian crowds has been recently become a topic of increasing relevance. In this paper, we consider the influence of the crowd motion in a complex dynamical environment on the course of…

Dynamical Systems · Mathematics 2021-01-06 Parveena Samim Abdul Salam , Wolfgang Bock , Axel Klar , Sudarshan Tiwari

The contact structure of a population plays an important role in transmission of infection. Many ``structured models'' capture aspects of the contact structure through an underlying network or a mixing matrix. An important observation in…

Populations and Evolution · Quantitative Biology 2020-07-15 Francesco Di Lauro , Luc Berthouze , Matthew D. Dorey , Joel C. Miller , István Z. Kiss

The spread of sexually transmitted diseases (e.g. Chlamydia, Syphilis, Gonorrhea, HIV) across populations is a major concern for scientists and health agencies. In this context, both data collection on sexual contact networks and the…

Physics and Society · Physics 2009-11-13 J. Gomez-Gardenes , V. Latora , Y. Moreno , E. V. Profumo

Coupling within-host infection dynamics with population-level transmission remains a major challenge in infectious disease modeling, especially for airborne pathogens with potential to spread indoor. The frequent emergence of such diseases…

Analysis of PDEs · Mathematics 2025-12-18 Andrew Omame , Sarafa Iyaniwura

We will study a mathematical model of the human immunodeficiency virus (HIV) infection in the presence of combination therapy that includes within-host infectious dynamics. The deterministic model requires us to analyze asymptotic stability…

Populations and Evolution · Quantitative Biology 2017-09-04 Majid Jaberi Douraki

The WHO 2021 malaria report revealed that its Global Technical Strategy (GTS) 2020 milestones for morbidity and mortality, based on the 2015 baseline, have not been achieved globally -- the world is off-track by 42% and, can be extended up…

Populations and Evolution · Quantitative Biology 2025-02-25 Laxmi , Tamer Oraby , Michael G Tyshenko , Ina Danquah , Samit Bhattacharyya

In the post-pandemic era of COVID-19, hospitalization remains a primary public health concern and wastewater surveillance has become an important tool for monitoring its dynamics at the level of community. However, there is usually no…

Methodology · Statistics 2026-01-14 K. Ken Peng , Charmaine B. Dean , Robert Delatolla , X. Joan Hu , Elizabeth Renouf

The propagation of infectious diseases and its impact on individuals play a major role in disease dynamics, and it is important to incorporate population heterogeneity into efforts to study diseases. As a simplistic but illustrative…

Populations and Evolution · Quantitative Biology 2019-07-24 Juan G. Calvo , Alberto Hernández , Mason A. Porter , Fabio Sanchez

The study proposes a modeling framework for investigating the disease dynamics with adaptive human behavior during a disease outbreak, considering the impacts of both local observations and global information. One important application…

Physics and Society · Physics 2020-08-26 Xinwu Qian , Jiawei Xue , Satish V. Ukkusuri

Understanding the dynamics of the spread of diseases within populations is critical for effective public health interventions. We extend the classical SIR model by incorporating additional complexities such as the introduction of a cure and…

Populations and Evolution · Quantitative Biology 2025-10-30 Daniel Perkins , Davis Hunter , Drake Brown , Trevor Garrity , Wyatt Pochman