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When applying multi-instance learning (MIL) to make predictions for bags of instances, the prediction accuracy of an instance often depends on not only the instance itself but also its context in the corresponding bag. From the viewpoint of…

Computer Vision and Pattern Recognition · Computer Science 2022-04-25 Tiancheng Lin , Hongteng Xu , Canqian Yang , Yi Xu

Multiple Instance Learning (MIL) involves predicting a single label for a bag of instances, given positive or negative labels at bag-level, without accessing to label for each instance in the training phase. Since a positive bag contains…

Machine Learning · Computer Science 2020-09-09 Beomjo Shin , Junsu Cho , Hwanjo Yu , Seungjin Choi

Fact verification datasets are typically constructed using crowdsourcing techniques due to the lack of text sources with veracity labels. However, the crowdsourcing process often produces undesired biases in data that cause models to learn…

Computation and Language · Computer Science 2021-10-01 Minwoo Lee , Seungpil Won , Juae Kim , Hwanhee Lee , Cheoneum Park , Kyomin Jung

Digitizing pathological images into gigapixel Whole Slide Images (WSIs) has opened new avenues for Computational Pathology (CPath). As positive tissue comprises only a small fraction of gigapixel WSIs, existing Multiple Instance Learning…

Computer Vision and Pattern Recognition · Computer Science 2025-09-16 Wenhao Tang , Sheng Huang , Heng Fang , Fengtao Zhou , Bo Liu , Qingshan Liu

Contrastive Learning (CL) performances as a rising approach to address the challenge of sparse and noisy recommendation data. Although having achieved promising results, most existing CL methods only perform either hand-crafted data or…

Information Retrieval · Computer Science 2023-11-22 Xiuyuan Qin , Huanhuan Yuan , Pengpeng Zhao , Junhua Fang , Fuzhen Zhuang , Guanfeng Liu , Victor Sheng

Recent works have advanced the performance of self-supervised representation learning by a large margin. The core among these methods is intra-image invariance learning. Two different transformations of one image instance are considered as…

Computer Vision and Pattern Recognition · Computer Science 2021-05-14 Haiping Wu , Xiaolong Wang

With the development of computational pathology, deep learning methods for Gleason grading through whole slide images (WSIs) have excellent prospects. Since the size of WSIs is extremely large, the image label usually contains only…

Computer Vision and Pattern Recognition · Computer Science 2022-06-28 Hao Bian , Zhuchen Shao , Yang Chen , Yifeng Wang , Haoqian Wang , Jian Zhang , Yongbing Zhang

Quantifying and evaluating image complexity can be instrumental in enhancing the performance of various computer vision tasks. Supervised learning can effectively learn image complexity features from well-annotated datasets. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-08-07 Shipeng Liu , Liang Zhao , Dengfeng Chen , Zhanping Song

Contrastive learning (CL) is a popular technique for self-supervised learning (SSL) of visual representations. It uses pairs of augmentations of unlabeled training examples to define a classification task for pretext learning of a deep…

Computer Vision and Pattern Recognition · Computer Science 2020-10-26 Chih-Hui Ho , Nuno Vasconcelos

Contrastive pretraining is well-known to improve downstream task performance and model generalisation, especially in limited label settings. However, it is sensitive to the choice of augmentation pipeline. Positive pairs should preserve…

Computer Vision and Pattern Recognition · Computer Science 2025-06-17 Melanie Roschewitz , Fabio De Sousa Ribeiro , Tian Xia , Galvin Khara , Ben Glocker

Domain shift in the field of histopathological imaging is a common phenomenon due to the intra- and inter-hospital variability of staining and digitization protocols. The implementation of robust models, capable of creating generalized…

Computer Vision and Pattern Recognition · Computer Science 2024-12-06 Ilán Carretero , Pablo Meseguer , Rocío del Amor , Valery Naranjo

Computer-aided pathology diagnosis based on the classification of Whole Slide Image (WSI) plays an important role in clinical practice, and it is often formulated as a weakly-supervised Multiple Instance Learning (MIL) problem. Existing…

Computer Vision and Pattern Recognition · Computer Science 2022-10-11 Linhao Qu , Xiaoyuan Luo , Manning Wang , Zhijian Song

In computational pathology, multiple instance learning (MIL) is widely used to circumvent the computational impasse in giga-pixel whole slide image (WSI) analysis. It usually consists of two stages: patch-level feature extraction and…

Image and Video Processing · Electrical Eng. & Systems 2023-09-21 Beidi Zhao , Wenlong Deng , Zi Han , Li , Chen Zhou , Zuhua Gao , Gang Wang , Xiaoxiao Li

We present a pioneering investigation into the application of deep learning techniques to analyze histopathological images for addressing the substantial challenge of automated prognostic prediction. Prognostic prediction poses a unique…

Unsupervised feature learning has made great strides with contrastive learning based on instance discrimination and invariant mapping, as benchmarked on curated class-balanced datasets. However, natural data could be highly correlated and…

Computer Vision and Pattern Recognition · Computer Science 2021-05-18 Xudong Wang , Ziwei Liu , Stella X. Yu

Whole slide image (WSI) classification is an essential task in computational pathology. Despite the recent advances in multiple instance learning (MIL) for WSI classification, accurate classification of WSIs remains challenging due to the…

Computer Vision and Pattern Recognition · Computer Science 2023-07-06 Saisai Ding , Jun Wang , Juncheng Li , Jun Shi

Graph-based Multiple Instance Learning (MIL) is widely used in survival analysis with Hematoxylin and Eosin (H\&E)-stained whole slide images (WSIs) due to its ability to capture topological information. However, variations in staining and…

Computer Vision and Pattern Recognition · Computer Science 2025-09-25 Min Cen , Zhenfeng Zhuang , Yuzhe Zhang , Min Zeng , Baptiste Magnier , Lequan Yu , Hong Zhang , Liansheng Wang

How to fast and accurately assess the severity level of COVID-19 is an essential problem, when millions of people are suffering from the pandemic around the world. Currently, the chest CT is regarded as a popular and informative imaging…

Image and Video Processing · Electrical Eng. & Systems 2021-02-09 Zekun Li , Wei Zhao , Feng Shi , Lei Qi , Xingzhi Xie , Ying Wei , Zhongxiang Ding , Yang Gao , Shangjie Wu , Jun Liu , Yinghuan Shi , Dinggang Shen

Digital pathology archives increasingly contain multiple whole-slide images (WSIs) per case, capturing spatially distinct tumour regions and reflecting intrinsic morphological heterogeneity. However, most existing approaches rely on a…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Zahra Rahimi Afzal , Wataru Uegami , Saghir Alfasly , Saba Yasir , Judy C. Boughey , Matthew P. Goetz , Krishna R. Kalari , H. R. Tizhoosh

Contrastive learning has led to substantial improvements in the quality of learned embedding representations for tasks such as image classification. However, a key drawback of existing contrastive augmentation methods is that they may lead…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Zhibo Zhang , Jongseong Jang , Chiheb Trabelsi , Ruiwen Li , Scott Sanner , Yeonjeong Jeong , Dongsub Shim