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We construct a nonstandard finite difference (NSFD) scheme for an SIRS mathematical model of respiratory virus transmission. This discretization is in full compliance with the NSFD methodology as formulated by R. E. Mickens. By use of an…

Populations and Evolution · Quantitative Biology 2010-08-16 Ronald E. Mickens , Talitha M. Washington

The SIR model is one of the most prototypical compartmental models in epidemiology. Generalizing this ordinary differential equation (ODE) framework into a spatially distributed partial differential equation (PDE) model is a considerable…

Quantitative Methods · Quantitative Biology 2024-07-11 Su Yang , Weiqi Chu , Panayotis Kevrekidis

Ordinary differential equations (ODE) are a popular tool to model the spread of infectious diseases, yet they implicitly assume an exponential distribution to describe the flow from one infection state to another. However, scientific…

Numerical Analysis · Mathematics 2025-10-13 Anna Wendler , Lena Plötzke , Hannah Tritzschak , Martin J. Kühn

In this work, we propose a generalized, second-order, nonstandard finite difference (NSFD) method for non-autonomous dynamical systems. The proposed method combines the NSFD framework with a new non-local approximation of the right-hand…

Numerical Analysis · Mathematics 2025-10-07 Manh Tuan Hoang , Matthias Ehrhardt

Reaction-diffusion epidemic models with vital dynamics are an important framework for describing the spatial and temporal spread of infectious diseases. In this work, we present a constraint-aware, physics-informed neural network (PINN)…

Dynamical Systems · Mathematics 2026-05-20 Achraf Zinihi , Matthias Ehrhardt

In this work, a class of continuous-time autonomous dynamical systems describing many important phenomena and processes arising in real-world applications is considered. We apply the nonstandard finite difference (NSFD) methodology proposed…

Numerical Analysis · Mathematics 2023-11-28 Manh Tuan Hoang

In this article, we construct a numerical method for a stochastic version of the Susceptible Infected Susceptible (SIS) epidemic model, expressed by a suitable stochastic differential equation (SDE), by using the semi-discrete method to a…

Numerical Analysis · Mathematics 2023-07-28 Yiannis Kiouvrekis , Ioannis S. Stamatiou

In recent years, discrete fractional epidemic models with reaction-diffusion have become increasingly popular in the literature, not only for its necessity of numerical simulation, but also for its defined physical processes. In this paper,…

Numerical Analysis · Mathematics 2022-08-16 Lu Zhenzhen , Yu Yongguang , Xu Weiyi , Ren Guojian , Meng Xiangyun

Standard finite difference (SFD) schemes often suffer from limited stability regions, especially when applied in explicit setup to partial differential equations. To address this challenge, this study investigates the efficacy of…

Numerical Analysis · Mathematics 2025-08-20 Shweta Kumari , Mani Mehra

In this work, we derive a nonstandard finite difference scheme for the SICA (Susceptible-Infected-Chronic-AIDS) model and analyze the dynamical properties of the discretized system. We prove that the discretized model is dynamically…

Numerical Analysis · Mathematics 2021-05-28 Sandra Vaz , Delfim F. M. Torres

This work proposes and analyzes a family of spatially inhomogeneous epidemic models. This is our first effort to use stochastic partial differential equations (SPDEs) to model epidemic dynamics with spatial variations and environmental…

Dynamical Systems · Mathematics 2020-01-01 Dang H Nguyen , Nhu N Nguyen , George Yin

Propagation characteristics of a wave are defined by the dispersion relationship, from which the governing partial differential equation (PDE) can be recovered. PDEs are commonly solved numerically using the finite-difference (FD) method,…

Numerical Analysis · Mathematics 2021-07-29 Edward Caunt

This study investigates an SEIS PDE model with a free boundary, which captures the dynamics of epidemic transmission, including diseases like COVID-19. This parabolic PDE system is analyzed in a rotationally symmetric domain, and the…

Analysis of PDEs · Mathematics 2025-11-11 Aesol Jeon , Ki-Ahm Lee

This paper introduces a novel hybrid model combining Partial Differential Equations (PDEs) and Ordinary Differential Equations (ODEs) to simulate infectious disease dynamics across geographic regions. By leveraging the spatial detail of…

Dynamical Systems · Mathematics 2025-11-18 Kristina Kehrer , Martin Weiser , Tim Conrad

We consider a dynamical system, defined by a system of autonomous differential equations, on $\Omega\subset\mathbb{R}^n$. By using Mickens' rule on the nonlocal approximation of nonlinear terms, we construct an implicit Nonstandard Finite…

Numerical Analysis · Mathematics 2022-07-26 Roumen Anguelov , Jean Lubuma

We study an SEIQR (Susceptible-Exposed-Infectious-Quarantined-Recovered) model for an infectious disease, with time delays for latency and an asymptomatic phase. For fast pandemics where nobody has prior immunity and everyone has immunity…

Populations and Evolution · Quantitative Biology 2020-04-09 C. P. Vyasarayani , Anindya Chatterjee

We study the construction of a non-standard finite differences numerical scheme for a general class of two dimensional differential equations including several models in population dynamics using the idea of non-local approximation…

Numerical Analysis · Mathematics 2014-10-27 Jacky Cresson , Frédéric Pierret

This paper introduces a spatiotemporal SEIQR epidemic model governed by a system of reaction-diffusion partial differential equations that incorporates optimal control strategies. The model captures the transmission dynamics of an…

Dynamical Systems · Mathematics 2025-07-29 Achraf Zinihi , Matthias Ehrhardt , Moulay Rchid Sidi Ammi

In this work, a novel second-order nonstandard finite difference (NSFD) method that preserves simultaneously the positivity and local asymptotic stability of one-dimensional autonomous dynamical systems is introduced and analyzed. This…

Numerical Analysis · Mathematics 2022-08-17 Manh Tuan Hoang

We propose a numerical method for approximating integro-differential equations arising in age-of-infection epidemic models. The method is based on a non-standard finite differences approximation of the integral term appearing in the…

Numerical Analysis · Mathematics 2024-07-22 Eleonora Messina , Mario Pezzella , Antonia Vecchio
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