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Machine learning algorithms can be fooled by small well-designed adversarial perturbations. This is reminiscent of cellular decision-making where ligands (called antagonists) prevent correct signalling, like in early immune recognition. We…

Biological Physics · Physics 2019-07-31 Thomas J. Rademaker , Emmanuel Bengio , Paul François

Online black-box optimization (BBO) aims to optimize an objective function by iteratively querying a black-box oracle in a sample-efficient way. While prior studies focus on forward approaches such as Gaussian Processes (GPs) to learn a…

Machine Learning · Computer Science 2025-02-04 Dongxia Wu , Nikki Lijing Kuang , Ruijia Niu , Yi-An Ma , Rose Yu

Equipping a deep model the abaility of few-shot learning, i.e., learning quickly from only few examples, is a core challenge for artificial intelligence. Gradient-based meta-learning approaches effectively address the challenge by learning…

Machine Learning · Computer Science 2024-01-09 Baoquan Zhang , Chuyao Luo , Demin Yu , Huiwei Lin , Xutao Li , Yunming Ye , Bowen Zhang

In recent years, the field of image generation has witnessed significant advancements, particularly in fine-tuning methods that align models with universal human preferences. This paper explores the critical role of preference data in the…

Computer Vision and Pattern Recognition · Computer Science 2025-03-24 Lingfan Zhang , Chen Liu , Chengming Xu , Kai Hu , Donghao Luo , Chengjie Wang , Yanwei Fu , Yuan Yao

Generative models such as diffusion have been employed as world models in offline reinforcement learning to generate synthetic data for more effective learning. Existing work either generates diffusion models one-time prior to training or…

Machine Learning · Computer Science 2024-05-31 Zeyu Fang , Tian Lan

Population-based evolutionary algorithms have great potential to handle multiobjective optimisation problems. However, these algorithms depends largely on problem characteristics, and there is a need to improve their performance for a wider…

Neural and Evolutionary Computing · Computer Science 2019-10-17 Shouyong Jiang , Hongru Li , Jinglei Guo , Mingjun Zhong , Shengxiang Yang , Marcus Kaiser , Natalio Krasnogor

Learning from a large corpus of data, pre-trained models have achieved impressive progress nowadays. As popular generative pre-training, diffusion models capture both low-level visual knowledge and high-level semantic relations. In this…

Computer Vision and Pattern Recognition · Computer Science 2023-03-20 Chaofan Ma , Yuhuan Yang , Chen Ju , Fei Zhang , Jinxiang Liu , Yu Wang , Ya Zhang , Yanfeng Wang

Diffusion-based models have gained significant popularity for text-to-image generation due to their exceptional image-generation capabilities. A risk with these models is the potential generation of inappropriate content, such as biased or…

Computer Vision and Pattern Recognition · Computer Science 2024-03-29 Hang Li , Chengzhi Shen , Philip Torr , Volker Tresp , Jindong Gu

Diffusion alignment aims to optimize diffusion models for the downstream objective. While existing methods based on reinforcement learning or direct backpropagation achieve considerable success in maximizing rewards, they often suffer from…

Machine Learning · Computer Science 2026-03-09 Jaewoo Lee , Minsu Kim , Sanghyeok Choi , Inhyuck Song , Sujin Yun , Hyeongyu Kang , Woocheol Shin , Taeyoung Yun , Kiyoung Om , Jinkyoo Park

The explosion in mobile data traffic together with the ever-increasing expectations for higher quality of service call for the development of AI algorithms for wireless network optimization. In this paper, we investigate how to learn…

Artificial Intelligence · Computer Science 2021-11-17 Miguel Suau , Alexandros Agapitos , David Lynch , Derek Farrell , Mingqi Zhou , Aleksandar Milenovic

To build effective therapeutics, biologists iteratively mutate antibody sequences to improve binding and stability. Proposed mutations can be informed by previous measurements or by learning from large antibody databases to predict only…

T cells are central to the adaptive immune response, capable of detecting pathogenic antigens while ignoring healthy tissues with remarkable specificity and sensitivity. Quantitatively understanding how T cell receptors (TCRs) discriminate…

Molecular Networks · Quantitative Biology 2025-11-25 François X. P. Bourassa , Sooraj Achar , Grégoire Altan-Bonnet , Paul François

Sensitivity to adversarial noise hinders deployment of machine learning algorithms in security-critical applications. Although many adversarial defenses have been proposed, robustness to adversarial noise remains an open problem. The most…

Machine Learning · Computer Science 2020-08-13 Alex Serban , Erik Poll , Joost Visser

This study proposes a UI interface generation method based on a diffusion model, aiming to achieve high-quality, diversified, and personalized interface design through generative artificial intelligence technology. The diffusion model is…

Human-Computer Interaction · Computer Science 2025-03-27 Yifei Duan , Liuqingqing Yang , Tong Zhang , Zhijun Song , Fenghua Shao

Meta learning aims at learning how to solve tasks, and thus it allows to estimate models that can be quickly adapted to new scenarios. This work explores distributionally robust minimization in meta learning for system identification.…

Machine Learning · Computer Science 2025-06-24 Matteo Rufolo , Dario Piga , Marco Forgione

In order to target threatening pathogens, the adaptive immune system performs a continuous reorganization of its lymphocyte repertoire. Following an immune challenge, the B cell repertoire can evolve cells of increased specificity for the…

Populations and Evolution · Quantitative Biology 2022-03-23 Victor Chardès , Massimo Vergassola , Aleksandra M. Walczak , Thierry Mora

In medical imaging, the heterogeneity of multi-centre data impedes the applicability of deep learning-based methods and results in significant performance degradation when applying models in an unseen data domain, e.g. a new centreor a new…

Computer Vision and Pattern Recognition · Computer Science 2020-08-12 Hongwei Li , Timo Loehr , Anjany Sekuboyina , Jianguo Zhang , Benedikt Wiestler , Bjoern Menze

The phenomenon of data distribution evolving over time has been observed in a range of applications, calling the needs of adaptive learning algorithms. We thus study the problem of supervised gradual domain adaptation, where labeled data…

Machine Learning · Computer Science 2022-11-15 Jing Dong , Shiji Zhou , Baoxiang Wang , Han Zhao

We frame the meta-learning of prediction procedures as a search for an optimal strategy in a two-player game. In this game, Nature selects a prior over distributions that generate labeled data consisting of features and an associated…

Machine Learning · Statistics 2020-09-29 Alex Luedtke , Incheoul Chung , Oleg Sofrygin

We propose a new problem formulation and a corresponding evaluation framework to advance research on unsupervised domain adaptation for semantic image segmentation. The overall goal is fostering the development of adaptive learning systems…

Computer Vision and Pattern Recognition · Computer Science 2022-03-31 Riccardo Volpi , Pau de Jorge , Diane Larlus , Gabriela Csurka