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Clinical decisions are high-stakes and require explicit justification, making model interpretability essential for auditing deep clinical models prior to deployment. As the ecosystem of model architectures and explainability methods…

Machine Learning · Computer Science 2026-03-27 Yongda Fan , John Wu , Andrea Fitzpatrick , Naveen Baskaran , Jimeng Sun , Adam Cross

We introduce MiRAGE, an evaluation framework for retrieval-augmented generation (RAG) from multimodal sources. As audiovisual media becomes a prevalent source of information online, it is essential for RAG systems to integrate information…

Computation and Language · Computer Science 2025-10-30 Alexander Martin , William Walden , Reno Kriz , Dengjia Zhang , Kate Sanders , Eugene Yang , Chihsheng Jin , Benjamin Van Durme

The increasing demand in artificial intelligence (AI) for models that are both effective and explainable is critical in domains where safety and trust are paramount. In this study, we introduce MIRA, a transparent and interpretable…

Artificial Intelligence · Computer Science 2024-10-18 Sarah Seifi , Tobias Sukianto , Cecilia Carbonelli , Lorenzo Servadei , Robert Wille

The wide-spread adoption of representation learning technologies in clinical decision making strongly emphasizes the need for characterizing model reliability and enabling rigorous introspection of model behavior. While the former need is…

Machine Learning · Computer Science 2020-05-01 Jayaraman J. Thiagarajan , Prasanna Sattigeri , Deepta Rajan , Bindya Venkatesh

Medical imaging is frequently used in clinical practice and trials for diagnosis and treatment. Writing imaging reports is time-consuming and can be error-prone for inexperienced radiologists. Therefore, automatically generating radiology…

Computation and Language · Computer Science 2022-04-29 Zhihong Chen , Yan Song , Tsung-Hui Chang , Xiang Wan

Medical imaging research is increasingly shifting from controlled benchmark evaluation toward real-world clinical deployment. In such settings, applying analytical methods extends beyond model design to require dataset-aware workflow…

Automation of medical image interpretation could alleviate bottlenecks in diagnostic workflows, and has become of particular interest in recent years due to advancements in natural language processing. Great strides have been made towards…

Artificial Intelligence · Computer Science 2024-08-01 Hermione Warr , Yasin Ibrahim , Daniel R. McGowan , Konstantinos Kamnitsas

Clinical diagnosis requires answers that are accurate, verifiable, and explicitly grounded in official guidelines. While large language models excel at natural language processing, their tendency to hallucinate undermines their utility in…

Artificial Intelligence · Computer Science 2026-05-29 Navapat Nananukul , Mayank Kejriwal

Evaluating agentic AI on open-ended professional tasks faces a fundamental dilemma between rigor and flexibility. Static rubrics provide rigorous, reproducible assessment but fail to accommodate diverse valid response strategies, while…

Artificial Intelligence · Computer Science 2026-02-09 Lanbo Lin , Jiayao Liu , Tianyuan Yang , Li Cai , Yuanwu Xu , Lei Wei , Sicong Xie , Guannan Zhang

Recently large vision-language models have shown potential when interpreting complex images and generating natural language descriptions using advanced reasoning. Medicine's inherently multimodal nature incorporating scans and text-based…

Image and Video Processing · Electrical Eng. & Systems 2024-07-15 Naman Sharma

The rapid expansion of scholarly literature presents significant challenges in synthesizing comprehensive, high-quality academic surveys. Recent advancements in agentic systems offer considerable promise for automating tasks that…

Digital Libraries · Computer Science 2025-11-25 Zi Wang , Xingqiao Wang , Sangah Lee , Xiaowei Xu

This paper develops a new approach for estimating an interpretable, relational model of a black-box autonomous agent that can plan and act. Our main contributions are a new paradigm for estimating such models using a minimal query interface…

Artificial Intelligence · Computer Science 2021-04-12 Pulkit Verma , Shashank Rao Marpally , Siddharth Srivastava

The discovery of causal relationships from high-dimensional data is a major open problem in bioinformatics. Machine learning and feature attribution models have shown great promise in this context but lack causal interpretation. Here, we…

Machine Learning · Computer Science 2023-04-26 Payam Dibaeinia , Saurabh Sinha

The clinical adoption of artificial intelligence (AI) in medical diagnostics is critically hampered by its black-box nature, which prevents clinicians from verifying the rationale behind automated decisions. To overcome this fundamental…

Diagnosing rare diseases presents a common challenge in clinical practice, necessitating the expertise of specialists for accurate identification. The advent of machine learning offers a promising solution, while the development of such…

Machine Learning · Computer Science 2024-03-12 Yifan Wu , Yang Liu , Yue Yang , Michael S. Yao , Wenli Yang , Xuehui Shi , Lihong Yang , Dongjun Li , Yueming Liu , James C. Gee , Xuan Yang , Wenbin Wei , Shi Gu

Evaluating GUI agents presents a distinct challenge: trajectories are long, visually grounded, and open-ended, yet evaluation must be both accurate and interpretable. Existing approaches typically apply a single holistic judgment over the…

Artificial Intelligence · Computer Science 2026-04-07 Yuwen Zhai , Runze Li , Liang Wang , Nian Shi , Liwu Xu , Wei Zhang , Ran Lin , Bo Xu , Benlei Cui

IMACT-CXR is an interactive multi-agent conversational tutor that helps trainees interpret chest X-rays by unifying spatial annotation, gaze analysis, knowledge retrieval, and image-grounded reasoning in a single AutoGen-based workflow. The…

Artificial Intelligence · Computer Science 2026-04-17 Tuan-Anh Le , Anh Mai Vu , David Yang , Akash Awasthi , Hien Van Nguyen

We propose a new automated evaluation metric for machine-generated radiology reports using the successful COMET architecture adapted for the radiology domain. We train and publish four medically-oriented model checkpoints, including one…

Computation and Language · Computer Science 2023-11-29 Amos Calamida , Farhad Nooralahzadeh , Morteza Rohanian , Koji Fujimoto , Mizuho Nishio , Michael Krauthammer

Automatic radiology report generation is booming due to its huge application potential for the healthcare industry. However, existing computer vision and natural language processing approaches to tackle this problem are limited in two…

Computer Vision and Pattern Recognition · Computer Science 2024-02-07 Fudan Zheng , Mengfei Li , Ying Wang , Weijiang Yu , Ruixuan Wang , Zhiguang Chen , Nong Xiao , Yutong Lu

Interactive machine reading comprehension (iMRC) is machine comprehension tasks where knowledge sources are partially observable. An agent must interact with an environment sequentially to gather necessary knowledge in order to answer a…

Computation and Language · Computer Science 2021-09-02 Xingdi Yuan
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