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To interpret the genetic profile present in a patient sample, it is necessary to know which mutations have important roles in the development of the corresponding cancer type. Named entity recognition is a core step in the text mining…

Computation and Language · Computer Science 2021-06-16 Jiarun Cao , Elke M van Veen , Niels Peek , Andrew G Renehan , Sophia Ananiadou

Variational autoencoders (VAEs) learn representations of data by jointly training a probabilistic encoder and decoder network. Typically these models encode all features of the data into a single variable. Here we are interested in learning…

Classifying breast cancer molecular subtypes is crucial for tailoring treatment strategies. While immunohistochemistry (IHC) and gene expression profiling are standard methods for molecular subtyping, IHC can be subjective, and gene…

Image and Video Processing · Electrical Eng. & Systems 2024-09-17 Masoud Tafavvoghi , Anders Sildnes , Mehrdad Rakaee , Nikita Shvetsov , Lars Ailo Bongo , Lill-Tove Rasmussen Busund , Kajsa Møllersen

Recommender systems have been studied extensively due to their practical use in many real-world scenarios. Despite this, generating effective recommendations with sparse user ratings remains a challenge. Side information associated with…

Information Retrieval · Computer Science 2018-07-17 Yifan Chen , Maarten de Rijke

This study explores the application of Quantum Convolutional Neural Networks (QCNNs) for brain tumor classification using MRI images, leveraging quantum computing for enhanced computational efficiency. A dataset of 3,264 MRI images,…

Classification using supervised learning requires annotating a large amount of classes-balanced data for model training and testing. This has practically limited the scope of applications with supervised learning, in particular deep…

Computer Vision and Pattern Recognition · Computer Science 2022-12-29 Hao Zhen , Yucheng Shi , Jidong J. Yang , Javad Mohammadpour Vehni

While unsupervised variational autoencoders (VAE) have become a powerful tool in neuroimage analysis, their application to supervised learning is under-explored. We aim to close this gap by proposing a unified probabilistic model for…

Machine Learning · Computer Science 2019-07-15 Qingyu Zhao , Ehsan Adeli , Nicolas Honnorat , Tuo Leng , Kilian M. Pohl

Molecular subtyping of cancer is recognized as a critical and challenging upstream task for personalized therapy. Existing deep learning methods have achieved significant performance in this domain when abundant data samples are available.…

Quantitative Methods · Quantitative Biology 2025-01-15 Ran Su , Rui Shi , Hui Cui , Ping Xuan , Chengyan Fang , Xikang Feng , Qiangguo Jin

Deep autoencoders are often extended with a supervised or adversarial loss to learn latent representations with desirable properties, such as greater predictivity of labels and outcomes or fairness with respects to a sensitive variable.…

Machine Learning · Statistics 2022-01-10 William E. Carson , Austin Talbot , David Carlson

Accurately quantifying uncertainty in predictions and projections arising from irreducible internal climate variability is critical for informed decision making. Such uncertainty is typically assessed using ensembles produced with physics…

Machine Learning · Computer Science 2026-02-09 Parsa Gooya , Reinel Sospedra-Alfonso , Johannes Exenberger

Machine learning can precisely identify different cancer tumors at any stage by classifying cancerous and healthy samples based on their genomic profile. We have developed novel methods of MLAC (Machine Learning Against Cancer) achieving…

Genomics · Quantitative Biology 2020-09-15 Arash Hooshmand

Artificial intelligence methods including deep neural networks (DNN) can provide rapid molecular classification of tumors from routine histology with accuracy that matches or exceeds human pathologists. Discerning how neural networks make…

The aim of this paper is to formalise the task of continual semi-supervised anomaly detection (CSAD), with the aim of highlighting the importance of such a problem formulation which assumes as close to real-world conditions as possible.…

Machine Learning · Computer Science 2024-12-03 Jack Belham , Aryan Bhosale , Samrat Mukherjee , Biplab Banerjee , Fabio Cuzzolin

We demonstrate a new deep learning autoencoder network, trained by a nonnegativity constraint algorithm (NCAE), that learns features which show part-based representation of data. The learning algorithm is based on constraining negative…

Machine Learning · Computer Science 2016-01-13 Ehsan Hosseini-Asl , Jacek M. Zurada , Olfa Nasraoui

Deep learning approaches to breast cancer detection in mammograms have recently shown promising results. However, such models are constrained by the limited size of publicly available mammography datasets, in large part due to privacy…

Computer Vision and Pattern Recognition · Computer Science 2018-08-27 Eric Wu , Kevin Wu , David Cox , William Lotter

Classifying brain tumors using magnetic resonance imaging (MRI) is crucial for early diagnosis and treatment; however, tumor heterogeneity and a dearth of annotated datasets restrict the use of supervised deep learning approaches. In this…

Unsupervised learning on high-dimensional RNA-seq data can reveal molecular subtypes beyond standard labels. We combine an autoencoder-based representation with clustering and stability analysis to search for rare but reproducible genomic…

Machine Learning · Computer Science 2025-11-18 Alaa Mezghiche

Cervical cancer is one of the most deadly and common diseases among women worldwide. It is completely curable if diagnosed in an early stage, but the tedious and costly detection procedure makes it unviable to conduct population-wise…

Computer Vision and Pattern Recognition · Computer Science 2021-10-25 Hritam Basak , Rohit Kundu , Sukanta Chakraborty , Nibaran Das

In this study, a deep learning based conditional density estimation technique known as conditional variational auto-encoder (CVAE) is used to fill gaps typically observed in particle image velocimetry (PIV) measurements in combustion…

Fluid Dynamics · Physics 2023-12-12 Shashank Yellapantula

Deep learning has enabled realistic face manipulation (i.e., deepfake), which poses significant concerns over the integrity of the media in circulation. Most existing deep learning techniques for deepfake detection can achieve promising…

Computer Vision and Pattern Recognition · Computer Science 2022-12-26 Bosheng Yan , Chang-Tsun Li , Xuequan Lu