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As recent text-conditioned diffusion models have enabled the generation of high-quality images, concerns over their potential misuse have also grown. This issue is critical in the medical domain, where text-conditioned generated medical…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Chanyoung Kim , Dayun Ju , Jinyeong Kim , Woojung Han , Roberto Alcover-Couso , Seong Jae Hwang

Transvaginal ultrasound is a critical imaging modality for evaluating cervical anatomy and detecting physiological changes. However, accurate segmentation of cervical structures remains challenging due to low contrast, shadow artifacts, and…

Computer Vision and Pattern Recognition · Computer Science 2025-04-18 Tran Quoc Khanh Le , Nguyen Lan Vi Vu , Ha-Hieu Pham , Xuan-Loc Huynh , Tien-Huy Nguyen , Minh Huu Nhat Le , Quan Nguyen , Hien D. Nguyen

Accurate semantic segmentation for histopathology image is crucial for quantitative tissue analysis and downstream clinical modeling. Recent segmentation foundation models have improved generalization through large-scale pretraining, yet…

Computer Vision and Pattern Recognition · Computer Science 2026-01-26 Peixian Liang , Songhao Li , Shunsuke Koga , Yutong Li , Zahra Alipour , Yucheng Tang , Daguang Xu , Zhi Huang

Color plays an important role in human visual perception, reflecting the spectrum of objects. However, the existing infrared and visible image fusion methods rarely explore how to handle multi-spectral/channel data directly and achieve high…

Computer Vision and Pattern Recognition · Computer Science 2024-10-28 Jun Yue , Leyuan Fang , Shaobo Xia , Yue Deng , Jiayi Ma

Breast cancer is one of the most common causes of cancer-related death in women worldwide. Early and accurate diagnosis of breast cancer may significantly increase the survival rate of patients. In this study, we aim to develop a fully…

Image and Video Processing · Electrical Eng. & Systems 2019-09-27 Sara Hosseinzadeh Kassani , Peyman Hosseinzadeh Kassani , Michal J. Wesolowski , Kevin A. Schneider , Ralph Deters

Histology imaging is an essential diagnosis method to finalize the grade and stage of cancer of different tissues, especially for breast cancer diagnosis. Specialists often disagree on the final diagnosis on biopsy tissue due to the complex…

Computer Vision and Pattern Recognition · Computer Science 2019-09-17 Yongxiang Huang , Albert Chi-shing Chung

Accurate whole-cell and nuclear segmentation is essential for precision pathology and spatial omics, yet routine hematoxylin and eosin (H&E) staining provides limited cytoplasmic contrast, restricting analyses to nuclei. Multiplex…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Yasin Shokrollahi , Karina B. Pinao Gonzales , Elizve N. Barrientos Toro , Paul Acosta , Patient Mosaic Team , Pingjun Chen , Yinyin Yuan , Xiaoxi Pan

Medical image classification has developed rapidly under the impetus of the convolutional neural network (CNN). Due to the fixed size of the receptive field of the convolution kernel, it is difficult to capture the global features of…

Image and Video Processing · Electrical Eng. & Systems 2022-09-22 Xiangzuo Huo , Gang Sun , Shengwei Tian , Yan Wang , Long Yu , Jun Long , Wendong Zhang , Aolun Li

Rheumatoid Arthritis (RA) is a chronic, autoimmune disease which primarily affects the joint's synovial tissue. It is a highly heterogeneous disease, with wide cellular and molecular variability observed in synovial tissues. Over the last…

Image and Video Processing · Electrical Eng. & Systems 2023-09-15 Amaya Gallagher-Syed , Abbas Khan , Felice Rivellese , Costantino Pitzalis , Myles J. Lewis , Gregory Slabaugh , Michael R. Barnes

Histopathology-based survival modelling has two major hurdles. Firstly, a well-performing survival model has minimal clinical application if it does not contribute to the stratification of a cancer patient cohort into different risk groups,…

Computer Vision and Pattern Recognition · Computer Science 2021-07-12 Hassan Muhammad , Chensu Xie , Carlie S. Sigel , Michael Doukas , Lindsay Alpert , William R. Jarnagin , Amber Simpson , Thomas J. Fuchs

Old-photo face restoration poses significant challenges due to compounded degradations such as breakage, fading, and severe blur. Existing pre-trained diffusion-guided methods either rely on explicit degradation priors or global statistical…

Computer Vision and Pattern Recognition · Computer Science 2025-10-15 Wenjie Li , Xiangyi Wang , Heng Guo , Guangwei Gao , Zhanyu Ma

Deep image restoration models aim to learn a mapping from degraded image space to natural image space. However, they face several critical challenges: removing degradation, generating realistic details, and ensuring pixel-level consistency.…

Computer Vision and Pattern Recognition · Computer Science 2025-07-31 Xinqi Lin , Fanghua Yu , Jinfan Hu , Zhiyuan You , Wu Shi , Jimmy S. Ren , Jinjin Gu , Chao Dong

Standard of care diagnostic procedure for suspected skin cancer is microscopic examination of hematoxylin \& eosin stained tissue by a pathologist. Areas of high inter-pathologist discordance and rising biopsy rates necessitate higher…

While human observers are able to cope with variations in color and appearance of histological stains, digital pathology algorithms commonly require a well-normalized setting to achieve peak performance, especially when a limited amount of…

Computer Vision and Pattern Recognition · Computer Science 2017-08-15 Daniel Bug , Steffen Schneider , Anne Grote , Eva Oswald , Friedrich Feuerhake , Julia Schüler , Dorit Merhof

Histopathology image segmentation is the gold standard for diagnosing cancer, and can indicate cancer prognosis. However, histopathology image segmentation requires high-quality masks, so many studies now use imagelevel labels to achieve…

Computer Vision and Pattern Recognition · Computer Science 2023-08-22 Liangrui Pan , Lian Wang , Zhichao Feng , Liwen Xu , Shaoliang Peng

Understanding the way cells communicate, co-locate, and interrelate is essential to furthering our understanding of how the body functions. H&E is widely available, however, cell subtyping often requires expert knowledge and the use of…

Breast cancer is the most common cancer among women worldwide. The human epidermal growth factor receptor 2 (HER2) with immunohistochemical (IHC) is widely used for pathological evaluation to provide the appropriate therapy for patients…

Quantitative Methods · Quantitative Biology 2022-03-08 Zichen Zhang , Lang Wang , Shuhao Wang

Learning high-quality, self-supervised, visual representations is essential to advance the role of computer vision in biomedical microscopy and clinical medicine. Previous work has focused on self-supervised representation learning (SSL)…

Computer Vision and Pattern Recognition · Computer Science 2023-03-06 Cheng Jiang , Xinhai Hou , Akhil Kondepudi , Asadur Chowdury , Christian W. Freudiger , Daniel A. Orringer , Honglak Lee , Todd C. Hollon

Crucial progress in our understanding of star formation and feedback will depend on the ability to obtain spatially resolved spectroscopic observations of \ion{H}{ii} regions, from which reliable instantaneous measurements of their physical…

This study evaluates the generalisation capabilities of state-of-the-art histopathology foundation models on out-of-distribution multi-stain autoimmune Immunohistochemistry datasets. We compare 13 feature extractor models, including…

Computer Vision and Pattern Recognition · Computer Science 2024-10-30 Amaya Gallagher-Syed , Elena Pontarini , Myles J. Lewis , Michael R. Barnes , Gregory Slabaugh
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