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Large foundation models, known for their strong zero-shot generalization, have excelled in visual and language applications. However, applying them to medical image segmentation, a domain with diverse imaging types and target labels,…

Image and Video Processing · Electrical Eng. & Systems 2024-04-18 Junde Wu , Jiayuan Zhu , Yueming Jin , Min Xu

The Segment Anything Model (SAM) and CLIP are remarkable vision foundation models (VFMs). SAM, a prompt driven segmentation model, excels in segmentation tasks across diverse domains, while CLIP is renowned for its zero shot recognition…

Computer Vision and Pattern Recognition · Computer Science 2024-05-01 Sidra Aleem , Fangyijie Wang , Mayug Maniparambil , Eric Arazo , Julia Dietlmeier , Guenole Silvestre , Kathleen Curran , Noel E. O'Connor , Suzanne Little

The rapid rise of large-scale foundation models has reshaped the landscape of image segmentation, with models such as Segment Anything achieving unprecedented versatility across diverse vision tasks. However, previous generations-including…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Tianrun Chen , Runlong Cao , Xinda Yu , Lanyun Zhu , Chaotao Ding , Deyi Ji , Cheng Chen , Qi Zhu , Chunyan Xu , Papa Mao , Ying Zang

Despite significant advances in deep learning for image and video segmentation, existing models continue to face challenges in cross-domain adaptability and generalization. Image and video segmentation are fundamental tasks in computer…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Zhang Jiaxing , Tang Hao

The Segment Anything Model (SAM) has demonstrated remarkable capabilities of scaled-up segmentation models, enabling zero-shot generalization across a variety of domains. By leveraging large-scale foundational models as pre-trained models,…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Weijia Feng , Lingting Zhu , Lequan Yu

Gliomas, the most prevalent primary brain tumors, require precise segmentation for diagnosis and treatment planning. However, this task poses significant challenges, particularly in the African population, were limited access to…

Image and Video Processing · Electrical Eng. & Systems 2023-12-20 Mohannad Barakat , Noha Magdy , Jjuuko George William , Ethel Phiri , Raymond Confidence , Dong Zhang , Udunna C Anazodo

Human preference alignment is critical in building powerful and reliable large language models (LLMs). However, current methods either ignore the multi-dimensionality of human preferences (e.g. helpfulness and harmlessness) or struggle with…

Machine Learning · Computer Science 2024-10-14 Xingzhou Lou , Junge Zhang , Jian Xie , Lifeng Liu , Dong Yan , Kaiqi Huang

Open-Vocabulary Segmentation (OVS) aims to segment image regions beyond predefined category sets by leveraging semantic descriptions. While CLIP based approaches excel in semantic generalization, they frequently lack the fine-grained…

Computer Vision and Pattern Recognition · Computer Science 2026-04-10 Haoxi Zeng , Qiankun Liu , Yi Bin , Haiyue Zhang , Yujuan Ding , Guoqing Wang , Deqiang Ouyang , Heng Tao Shen

Deep learning-based medical image segmentation typically requires large amount of labeled data for training, making it less applicable in clinical settings due to high annotation cost. Semi-supervised learning (SSL) has emerged as an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-03 Yichi Zhang , Bohao Lv , Le Xue , Wenbo Zhang , Yuchen Liu , Yu Fu , Yuan Cheng , Yuan Qi

Existing promptable segmentation methods in the medical imaging field primarily consider either textual or visual prompts to segment relevant objects, yet they often fall short when addressing anomalies in medical images, like tumors, which…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Zhongzhen Huang , Yankai Jiang , Rongzhao Zhang , Shaoting Zhang , Xiaofan Zhang

With the development of Deep Neural Networks (DNNs), many efforts have been made to handle medical image segmentation. Traditional methods such as nnUNet train specific segmentation models on the individual datasets. Plenty of recent…

Computer Vision and Pattern Recognition · Computer Science 2024-07-12 Xiaobao Wei , Jiajun Cao , Yizhu Jin , Ming Lu , Guangyu Wang , Shanghang Zhang

Interactive medical image segmentation refers to the accurate segmentation of the target of interest through interaction (e.g., click) between the user and the image. It has been widely studied in recent years as it is less dependent on…

Computer Vision and Pattern Recognition · Computer Science 2023-08-29 Ao Chang , Xing Tao , Xin Yang , Yuhao Huang , Xinrui Zhou , Jiajun Zeng , Ruobing Huang , Dong Ni

The Segment Anything Model 2 (SAM2) has recently demonstrated exceptional performance in zero-shot prompt segmentation for natural images and videos. However, when the propagation mechanism of SAM2 is applied to medical images, it often…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Yunhao Bai , Boxiang Yun , Zeli Chen , Qinji Yu , Yingda Xia , Yan Wang

The Segment Anything Model (SAM) has demonstrated strong and versatile segmentation capabilities, along with intuitive prompt-based interactions. However, customizing SAM for medical image segmentation requires massive amounts of…

Computer Vision and Pattern Recognition · Computer Science 2025-01-14 Zhonghao Yan , Zijin Yin , Tianyu Lin , Xiangzhu Zeng , Kongming Liang , Zhanyu Ma

The Segment Anything Model (SAM) and similar models build a family of promptable foundation models (FMs) for image and video segmentation. The object of interest is identified using prompts, such as bounding boxes or points. With these FMs…

Computer Vision and Pattern Recognition · Computer Science 2024-11-14 Caroline Magg , Hoel Kervadec , Clara I. Sánchez

Segmentation is a fundamental task in computer vision, with prompt-driven methods gaining prominence due to their flexibility. The Segment Anything Model (SAM) excels at point-prompted segmentation, while text-based models, often leveraging…

Computer Vision and Pattern Recognition · Computer Science 2025-09-23 Suzhe Xu , Jialin Peng , Chengyuan Zhang

The inverse folding problem, aiming to design amino acid sequences that fold into desired three-dimensional structures, is pivotal for various biotechnological applications. Here, we introduce a novel approach leveraging Direct Preference…

Machine Learning · Computer Science 2025-06-04 Junde Xu , Zijun Gao , Xinyi Zhou , Jie Hu , Xingyi Cheng , Le Song , Guangyong Chen , Pheng-Ann Heng , Jiezhong Qiu

We present SAM4EM, a novel approach for 3D segmentation of complex neural structures in electron microscopy (EM) data by leveraging the Segment Anything Model (SAM) alongside advanced fine-tuning strategies. Our contributions include the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-01 Uzair Shah , Marco Agus , Daniya Boges , Vanessa Chiappini , Mahmood Alzubaidi , Jens Schneider , Markus Hadwiger , Pierre J. Magistretti , Mowafa Househ , Corrado Calı

The remarkable capabilities of the Segment Anything Model (SAM) for tackling image segmentation tasks in an intuitive and interactive manner has sparked interest in the design of effective visual prompts. Such interest has led to the…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Jorge Quesada , Zoe Fowler , Mohammad Alotaibi , Mohit Prabhushankar , Ghassan AlRegib

The limited availability of labeled data has driven advancements in semi-supervised learning for medical image segmentation. Modern large-scale models tailored for general segmentation, such as the Segment Anything Model (SAM), have…

Computer Vision and Pattern Recognition · Computer Science 2024-12-19 Kaiwen Huang , Tao Zhou , Huazhu Fu , Yizhe Zhang , Yi Zhou , Chen Gong , Dong Liang
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