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The aim of the systematic review was to assess recently published studies on diagnostic test accuracy of glioblastoma treatment response monitoring biomarkers in adults, developed through machine learning (ML). Articles were searched for…

The optimal treatment strategy of newly diagnosed glioma is strongly influenced by tumour malignancy. Manual non-invasive grading based on MRI is not always accurate and biopsies to verify diagnosis negatively impact overall survival. In…

Image and Video Processing · Electrical Eng. & Systems 2019-08-08 Milan Decuyper , Roel Van Holen

Colorectal liver metastases (CLM) significantly impact colon cancer patients, influencing survival based on systemic chemotherapy response. Traditional methods like tumor grading scores (e.g., tumor regression grade - TRG) for prognosis…

Primary brain tumors including gliomas continue to pose significant management challenges to clinicians. While the presentation, the pathology, and the clinical course of these lesions are variable, the initial investigations are usually…

Image and Video Processing · Electrical Eng. & Systems 2020-04-13 Weina Jin , Mostafa Fatehi , Kumar Abhishek , Mayur Mallya , Brian Toyota , Ghassan Hamarneh

Glioma, a common and deadly brain tumor, requires early diagnosis for improved prognosis. However, low-quality Magnetic Resonance Imaging (MRI) technology in Sub-Saharan Africa (SSA) hinders accurate diagnosis. This paper presents our work…

Image and Video Processing · Electrical Eng. & Systems 2024-10-28 Yanguang Zhao , Long Bai , Zhaoxi Zhang , Yanan Wu , Mobarakol Islam , Hongliang Ren

In this work, we develop an attention convolutional neural network (CNN) to segment brain tumors from Magnetic Resonance Images (MRI). Further, we predict the survival rate using various machine learning methods. We adopt a 3D UNet…

Image and Video Processing · Electrical Eng. & Systems 2021-04-05 Mobarakol Islam , Vibashan VS , V Jeya Maria Jose , Navodini Wijethilake , Uppal Utkarsh , Hongliang Ren

Vision transformers (ViT) have been shown to allow for more flexible feature detection and can outperform convolutional neural network (CNN) when pre-trained on sufficient data. Due to their promising feature detection capabilities, we…

Computer Vision and Pattern Recognition · Computer Science 2026-04-16 Nghia , Nguyen , Amer Wahed , Andy Quesada , Yasir Ali , Hanadi El Achi , Y. Helen Zhang , Jocelyn Ursua , Alex Banerjee , Sahib Kalra , L. Jeffrey Medeiros , Jie Xu

The RSNA-MICCAI brain tumor radiogenomic classification challenge aimed to predict MGMT biomarker status in glioblastoma through binary classification on Multi parameter mpMRI scans: T1w, T1wCE, T2w and FLAIR. The dataset is splitted into…

Image and Video Processing · Electrical Eng. & Systems 2024-01-19 Amr Mohamed , Mahmoud Rabea , Aya Sameh , Ehab Kamal

Glioblastoma, a highly aggressive brain tumor, poses major challenges due to its poor prognosis and high morbidity rates. Partial differential equation-based models offer promising potential to enhance therapeutic outcomes by simulating…

Computer Vision and Pattern Recognition · Computer Science 2025-09-10 Zeineb Haouari , Jonas Weidner , Yeray Martin-Ruisanchez , Ivan Ezhov , Aswathi Varma , Daniel Rueckert , Bjoern Menze , Benedikt Wiestler

Radiomic models have been shown to outperform clinical data for outcome prediction in glioblastoma (GBM). However, clinical implementation is limited by lack of parameters standardization. We aimed to compare nine machine learning…

We proposed a fully automatic workflow for glioblastoma (GBM) survival prediction using deep learning (DL) methods. 285 glioma (210 GBM, 75 low-grade glioma) patients were included. 163 of the GBM patients had overall survival (OS) data.…

Medical Physics · Physics 2021-07-07 Jie Fu , Kamal Singhrao , Xinran Zhong , Yu Gao , Sharon Qi , Yingli Yang , Dan Ruan , John H Lewis

Breast cancer is still the second top cause of cancer deaths worldwide and this emphasizes the importance of necessary steps for early detection. Traditional diagnostic methods, such as mammography, ultrasound, and thermography, which have…

Glioblastoma is profoundly heterogeneous in regional microstructure and vasculature. Characterizing the spatial heterogeneity of glioblastoma could lead to more precise treatment. With unsupervised learning techniques, glioblastoma…

Machine Learning · Computer Science 2021-08-24 Yifan Li , Chao Li , Yiran Wei , Stephen Price , Carola-Bibiane Schönlieb , Xi Chen

Glioblastomas are the most aggressive type of glioma, having a 5-year survival rate of 6.9%. Treatment typically involves surgery, followed by radiotherapy and chemotherapy, and frequent magnetic resonance imaging (MRI) scans to monitor…

Image and Video Processing · Electrical Eng. & Systems 2025-06-05 Ana Matoso , Catarina Passarinho , Marta P. Loureiro , José Maria Moreira , Patrícia Figueiredo , Rita G. Nunes

This paper introduces a novel methodology to integrate human brain connectomics and parcellation for brain tumor segmentation and survival prediction. For segmentation, we utilize an existing brain parcellation atlas in the MNI152 1mm space…

Computer Vision and Pattern Recognition · Computer Science 2019-02-13 Po-Yu Kao , Thuyen Ngo , Angela Zhang , Jefferson W. Chen , B. S. Manjunath

Glioblastoma recurrence is largely driven by diffuse infiltration beyond radiologically visible tumor margins, yet standard radiotherapy, the mainstay of glioblastoma treatment, relies on uniform expansions that ignore patient-specific…

Image and Video Processing · Electrical Eng. & Systems 2026-03-17 L. Zimmer , J. Weidner , M. Balcerak , F. Kofler , M. Krupa , I. Ezhov , S. Cepeda , R. Zhang , J. Lowengrub , B. Menze , B. Wiestler

Glioblastoma (GBM) is one of the most aggressive and lethal human cancers. Intra-tumoral genetic heterogeneity poses a significant challenge for treatment. Biopsy is invasive, which motivates the development of non-invasive, MRI-based…

Glioblastoma (GBM) is a highly aggressive primary brain tumor with limited therapeutic options and poor prognosis. The methylation status of the O6-methylguanine-DNA methyltransferase (MGMT) gene promoter is a critical molecular biomarker…

Machine Learning · Computer Science 2026-01-13 Hasan M Jamil

Automatically segmenting sub-regions of gliomas (necrosis, edema and enhancing tumor) and accurately predicting overall survival (OS) time from multimodal MRI sequences have important clinical significance in diagnosis, prognosis and…

Image and Video Processing · Electrical Eng. & Systems 2019-12-17 Xiaoqing Guo , Chen Yang , Pak Lun Lam , Peter Y. M. Woo , Yixuan Yuan

Glioblastoma is a highly invasive brain tumor, whose cells infiltrate surrounding normal brain tissue beyond the lesion outlines visible in the current medical scans. These infiltrative cells are treated mainly by radiotherapy. Existing…