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Improving performance on complex tasks and enabling interpretable decision making in large language models (LLMs), especially for clinical applications, requires effective reasoning. Yet this remains challenging without supervised…

Computation and Language · Computer Science 2025-05-26 Che Liu , Haozhe Wang , Jiazhen Pan , Zhongwei Wan , Yong Dai , Fangzhen Lin , Wenjia Bai , Daniel Rueckert , Rossella Arcucci

Supervised fine-tuning (SFT) is essential for the development of medical large language models (LLMs), yet prior poisoning studies have mainly focused on the detectable backdoor attacks. We propose a novel poisoning attack targeting the…

Cryptography and Security · Computer Science 2026-03-04 Jingyuan Xie , Wenjie Wang , Ji Wu , Jiandong Gao

Clinical Question-Answering (CQA) industry systems are increasingly rely on Large Language Models (LLMs), yet their deployment is often guided by the assumption that domain-specific fine-tuning is essential. Although specialised medical…

Computation and Language · Computer Science 2026-01-21 Sushant Kumar Ray , Gautam Siddharth Kashyap , Sahil Tripathi , Nipun Joshi , Vijay Govindarajan , Rafiq Ali , Jiechao Gao , Usman Naseem

Large language models (LLMs), owing to their extensive open-domain knowledge and semantic reasoning capabilities, have been increasingly integrated into recommender systems (RS). However, a substantial gap remains between the pre-training…

Information Retrieval · Computer Science 2026-01-27 Bohao Wang , Jiawei Chen , Feng Liu , Changwang Zhang , Jun Wang , Canghong Jin , Chun Chen , Can Wang

Current Large Language Models (LLMs) exhibit significant limitations, notably in structured, interpretable, and verifiable medical reasoning, alongside practical deployment challenges related to computational resources and data privacy.…

Computation and Language · Computer Science 2025-06-06 Boqin Zhuang , Chenxiao Song , Huitong Lu , Jiacheng Qiao , Mingqian Liu , Mingxing Yu , Ping Hong , Rui Li , Xiaoxia Song , Xiangjun Xu , Xu Chen , Yaoyao Ma , Yujie Gao

Large language models have driven significant progress in natural language processing, but their deployment requires substantial compute and memory resources. As models scale, compression techniques become essential for balancing model…

Machine Learning · Computer Science 2025-05-13 Vithursan Thangarasa , Ganesh Venkatesh , Mike Lasby , Nish Sinnadurai , Sean Lie

Multimodal large language models (MLLMs) have made rapid progress, yet their reasoning ability often lags behind strong text-only LLMs. Bridging this gap typically requires large-scale multimodal reasoning data or reinforcement learning,…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Chao Huang , Zeliang Zhang , Jiang Liu , Ximeng Sun , Jialian Wu , Xiaodong Yu , Ze Wang , Chenliang Xu , Emad Barsoum , Zicheng Liu

Accurate clinical diagnosis requires extensive domain knowledge and complex clinical reasoning capabilities. Although large language models (LLMs) hold great potential for clinical reasoning, their high computational and memory requirements…

Computers and Society · Computer Science 2026-05-12 Xinchun Su , Chunxu Luo , Lipeng Ma , Yixuan Li , Weidong Yang

Despite the effectiveness of data selection for large language models (LLMs) during pretraining and instruction fine-tuning phases, improving data efficiency in supervised fine-tuning (SFT) for specialized domains poses significant…

Computation and Language · Computer Science 2024-12-06 Yu Yang , Siddhartha Mishra , Jeffrey N Chiang , Baharan Mirzasoleiman

Supervised fine-tuning (SFT) plays a crucial role in adapting large language models (LLMs) to specific domains or tasks. However, as demonstrated by empirical experiments, the collected data inevitably contains noise in practical…

Computation and Language · Computer Science 2024-12-20 Junyu Luo , Xiao Luo , Kaize Ding , Jingyang Yuan , Zhiping Xiao , Ming Zhang

Diffusion models have recently shown strong potential in language modeling, offering faster generation compared to traditional autoregressive approaches. However, applying supervised fine-tuning (SFT) to diffusion models remains…

Computation and Language · Computer Science 2026-05-12 Guowei Xu , Wenxin Xu , Jiawang Zhao , Kaisheng Ma

Supervised fine-tuning (SFT) provides the standard approach for teaching LLMs new behaviors from offline expert demonstrations. However, standard SFT uniformly fits all samples -- including those with low likelihood under the base model --…

Machine Learning · Computer Science 2026-05-15 Mahdi Sabbaghi , George Pappas , Adel Javanmard , Hamed Hassani

High-quality and carefully curated data is a cornerstone of training medical large language models, as it directly impacts both generalization and robustness to unseen clinical tasks. We investigate strategies for training and data curation…

Artificial Intelligence · Computer Science 2025-12-01 Timothy Ossowski , Sheng Zhang , Qianchu Liu , Guanghui Qin , Reuben Tan , Tristan Naumann , Junjie Hu , Hoifung Poon

This paper explores a scientific question in supervised fine-tuning (SFT): why SFT is broadly effective for small-scale deep neural networks, yet can produce inconsistent or even detrimental effects when applied to large language models…

Artificial Intelligence · Computer Science 2026-05-19 Junpeng Zhang , Lei Cheng , Guoxi Zhang , Hua Cai , Qing Xu , Quanshi Zhang

Supervised fine-tuning (SFT) is fundamental to adapting large language models, yet training on complete datasets incurs prohibitive costs with diminishing returns. Existing data selection methods suffer from severe domain specificity:…

Computation and Language · Computer Science 2026-02-02 Junyou Su , He Zhu , Xiao Luo , Liyu Zhang , Hong-Yu Zhou , Yun Chen , Peng Li , Yang Liu , Guanhua Chen

Large language models (LLMs) have demonstrated remarkable performance across a wide range of tasks. Advances in prompt engineering and fine-tuning techniques have further enhanced their ability to address complex reasoning challenges.…

Computation and Language · Computer Science 2024-12-16 Jing Bi , Yuting Wu , Weiwei Xing , Zhenjie Wei

Accurate disease classification from radiology reports is essential for many applications. While supervised fine-tuning (SFT) of lightweight LLMs improves accuracy, it can degrade reasoning. We propose a two-stage approach: SFT on disease…

Artificial Intelligence · Computer Science 2026-04-22 Yishu Wei , Yi Lin , Adam Flanders , George Shih , Yifan Peng

Large language models (LLMs) have demonstrated significant progress in multilingual language understanding and generation. However, due to the imbalance in training data, their capabilities in non-English languages are limited. Recent…

Computation and Language · Computer Science 2025-03-06 Wenshuai Huo , Xiaocheng Feng , Yichong Huang , Chengpeng Fu , Baohang Li , Yangfan Ye , Zhirui Zhang , Dandan Tu , Duyu Tang , Yunfei Lu , Hui Wang , Bing Qin

Open-source, multilingual medical large language models (LLMs) have the potential to serve linguistically diverse populations across different regions. Adapting generic LLMs for healthcare often requires continual pretraining, but this…

Computation and Language · Computer Science 2024-09-10 Meng Zhou , Surajsinh Parmar , Anubhav Bhatti

Fine-tuning Large Language Models (LLMs) on specific datasets is a common practice to improve performance on target tasks. However, this performance gain often leads to overfitting, where the model becomes too specialized in either the task…

Computation and Language · Computer Science 2025-02-21 Sonam Gupta , Yatin Nandwani , Asaf Yehudai , Dinesh Khandelwal , Dinesh Raghu , Sachindra Joshi