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Target Safety Assessment (TSA) requires systematic integration of heterogeneous evidence, including genetic, transcriptomic, target homology, pharmacological, and clinical data, to evaluate potential safety liabilities of therapeutic…

Computation and Language · Computer Science 2026-05-11 Xiaochen Zheng , Zhiwen Jiang , Melanie Guerard , Klas Hatje , Tatyana Doktorova

The automation of the medical evidence acquisition and diagnosis process has recently attracted increasing attention in order to reduce the workload of doctors and democratize access to medical care. However, most works proposed in the…

Computation and Language · Computer Science 2022-10-14 Arsene Fansi Tchango , Rishab Goel , Julien Martel , Zhi Wen , Gaetan Marceau Caron , Joumana Ghosn

A formal but intuitive framework is introduced to bridge the gap between data obtained from empirical studies and that generated by agent-based models. This is based on three key tenets. Firstly, a simulation can be given multiple formal…

Multiagent Systems · Computer Science 2013-02-21 Chih-Chun Chen

Large language models (LLMs) and vision-language models (VLMs) have the potential to transform biological research by enabling autonomous experimentation. Yet, their application remains constrained by rigid protocol design, limited…

Robotics · Computer Science 2025-07-03 Yibo Qiu , Zan Huang , Zhiyu Wang , Handi Liu , Yiling Qiao , Yifeng Hu , Shu'ang Sun , Hangke Peng , Ronald X Xu , Mingzhai Sun

Modeling human-human interactions from text remains challenging because it requires not only realistic individual dynamics but also precise, text-consistent spatiotemporal coupling between agents. Currently, progress is hindered by 1)…

Computer Vision and Pattern Recognition · Computer Science 2025-10-09 Qingxuan Wu , Zhiyang Dou , Chuan Guo , Yiming Huang , Qiao Feng , Bing Zhou , Jian Wang , Lingjie Liu

Existing multimodal retrieval systems excel at semantic matching but implicitly assume that query-image relevance can be measured in isolation. This paradigm overlooks the rich dependencies inherent in realistic visual streams, where…

Computer Vision and Pattern Recognition · Computer Science 2026-02-12 Chenlong Deng , Mengjie Deng , Junjie Wu , Dun Zeng , Teng Wang , Qingsong Xie , Jiadeng Huang , Shengjie Ma , Changwang Zhang , Zhaoxiang Wang , Jun Wang , Yutao Zhu , Zhicheng Dou

Multimodal empathetic response generation (MERG) aims to generate emotionally engaging and empathetic responses based on users' multimodal contexts. Existing approaches usually rely on an implicit one-pass generation paradigm from…

Computer Vision and Pattern Recognition · Computer Science 2026-04-22 Liping Wang , Cheng Ye , Weidong Chen , Peipei Song , Bo Hu , Zhendong Mao

Bias in medical artificial intelligence is conventionally viewed as a defect requiring elimination. However, human reasoning inherently incorporates biases shaped by education, culture, and experience, suggesting their presence may be…

Artificial Intelligence · Computer Science 2026-03-05 Farhad Abtahi , Mehdi Astaraki , Fernando Seoane

Recent progress in generative models has stimulated significant innovations in many fields, such as image generation and chatbots. Despite their success, these models often produce sketchy and misleading solutions for complex multi-agent…

Artificial Intelligence · Computer Science 2024-10-04 Zeyang Liu , Xinrui Yang , Shiguang Sun , Long Qian , Lipeng Wan , Xingyu Chen , Xuguang Lan

The history of science is punctuated by serendipitous discoveries, where unexpected observations, rather than targeted hypotheses, opened new fields of inquiry. While modern autonomous laboratories excel at accelerating hypothesis testing,…

Artificial Intelligence · Computer Science 2025-08-12 Lance Yao , Suman Samantray , Ayana Ghosh , Kevin Roccapriore , Libor Kovarik , Sarah Allec , Maxim Ziatdinov

LLM-based agents have demonstrated strong potential for autonomous machine learning, yet their applicability to health data remains limited. Existing systems often struggle to generalize across heterogeneous health data modalities, rely…

Artificial Intelligence · Computer Science 2026-02-03 Tong Xia , Weibin Li , Gang Liu , Yong Li

Rare disease diagnosis is inherently challenging due to heterogeneous symptoms, limited clinical familiarity, and fragmented evidence across specialties. Recent large language model (LLM)-based agentic systems have shown promise by…

Human-Computer Interaction · Computer Science 2026-03-31 Peng Kuai , Yukun Yang , Shaolun Ruan , Junchi Xu , Yanjie Zhang , Lin Zhang , Min Zhu , Rui Sheng

Large Language Models (LLMs) have demonstrated potential in automating scientific ideation, yet current approaches relying on iterative prompting or complex multi-agent architectures often suffer from hallucination or computational…

Population-population generalization is a challenging problem in multi-agent reinforcement learning (MARL), particularly when agents encounter unseen co-players. However, existing self-play-based methods are constrained by the limitation of…

Machine Learning · Computer Science 2025-05-19 Lang Feng , Jiahao Lin , Dong Xing , Li Zhang , De Ma , Gang Pan

Multi-agent debate (MAD) is an emerging approach to improving the reasoning capabilities of large language models (LLMs). Existing MAD methods rely on multiple rounds of interaction among agents to reach consensus, and the final output is…

Artificial Intelligence · Computer Science 2025-09-16 Yu Cui , Hang Fu , Haibin Zhang , Licheng Wang , Cong Zuo

The rapid evolution of AI-generated images poses growing challenges to information integrity and media authenticity. Existing detection approaches face limitations in robustness, interpretability, and generalization across diverse…

Computer Vision and Pattern Recognition · Computer Science 2026-04-08 Mengfei Liang , Yiting Qu , Yukun Jiang , Michael Backes , Yang Zhang

We introduce a new dataset, MELINDA, for Multimodal biomEdicaL experImeNt methoD clAssification. The dataset is collected in a fully automated distant supervision manner, where the labels are obtained from an existing curated database, and…

Computation and Language · Computer Science 2020-12-18 Te-Lin Wu , Shikhar Singh , Sayan Paul , Gully Burns , Nanyun Peng

A critical limitation in large-scale multi-agent systems is the cascading of errors. And without intermediate verification, downstream agents exacerbate upstream inaccuracies, resulting in significant quality degradation. To bridge this…

Multiagent Systems · Computer Science 2026-03-18 Churong Liang , Jinling Gan , Kairan Hong , Qiushi Tian , Zongze Wu , Runnan Li

Relational event network data are becoming increasingly available. Consequently, statistical models for such data have also surfaced. These models mainly focus on the analysis of single networks, while in many applications, multiple…

Methodology · Statistics 2023-06-08 Fabio Vieira , Roger Leenders , Daniel McFarland , Joris Mulder

In Biomedical Natural Language Processing (BioNLP) tasks, such as Relation Extraction, Named Entity Recognition, and Text Classification, the scarcity of high-quality data remains a significant challenge. This limitation poisons large…

Computation and Language · Computer Science 2025-04-01 Zhengyi Zhao , Shubo Zhang , Bin Liang , Binyang Li , Kam-Fai Wong
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