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Deep learning has shown its great promise in various biomedical image segmentation tasks. Existing models are typically based on U-Net and rely on an encoder-decoder architecture with stacked local operators to aggregate long-range…

Computer Vision and Pattern Recognition · Computer Science 2020-02-20 Zhengyang Wang , Na Zou , Dinggang Shen , Shuiwang Ji

Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Cell Behavior · Quantitative Biology 2017-10-31 Mo Zhang , Xiang Li , Mengjia Xu , Quanzheng Li

Diffusion models have become a leading approach for high-fidelity medical image synthesis. However, most existing methods for 3D medical image generation rely on convolutional U-Net backbones within latent diffusion frameworks. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-27 Marvin Seyfarth , Salman Ul Hassan Dar , Yannik Frisch , Philipp Wild , Norbert Frey , Florian André , Sandy Engelhardt

Medical image segmentation is a critical task in clinical workflows, particularly for the detection and delineation of pathological regions. While convolutional architectures like U-Net have become standard for such tasks, their limited…

Computer Vision and Pattern Recognition · Computer Science 2025-09-09 Morteza Kiani Haftlang , Mohammadhossein Malmir , Foroutan Parand , Umberto Michelucci , Safouane El Ghazouali

Modern microscopy routinely produces gigapixel images that contain structures across multiple spatial scales, from fine cellular morphology to broader tissue organization. Many analysis tasks require combining these scales, yet most vision…

Computer Vision and Pattern Recognition · Computer Science 2026-03-02 Albert Dominguez Mantes , Gioele La Manno , Martin Weigert

For 3D medical image (e.g. CT and MRI) segmentation, the difficulty of segmenting each slice in a clinical case varies greatly. Previous research on volumetric medical image segmentation in a slice-by-slice manner conventionally use the…

Image and Video Processing · Electrical Eng. & Systems 2022-07-12 Wenxuan Wang , Chen Chen , Jing Wang , Sen Zha , Yan Zhang , Jiangyun Li

The accurate analysis of medical images is vital for diagnosing and predicting medical conditions. Traditional approaches relying on radiologists and clinicians suffer from inconsistencies and missed diagnoses. Computer-aided diagnosis…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Yulong Shisu , Susano Mingwin , Yongshuai Wanwag , Zengqiang Chenso , Sunshin Huing

Segmentation in 3D scans is playing an increasingly important role in current clinical practice supporting diagnosis, tissue quantification, or treatment planning. The current 3D approaches based on convolutional neural networks usually…

Computer Vision and Pattern Recognition · Computer Science 2019-03-12 Alexey Novikov , David Major , Maria Wimmer , Dimitrios Lenis , Katja Bühler

Vision Transformers (ViTs) have gained rapid adoption in computational pathology for their ability to model long-range dependencies through self-attention, addressing the limitations of convolutional neural networks that excel at local…

Image and Video Processing · Electrical Eng. & Systems 2026-01-15 Fuyao Chen , Yuexi Du , Elèonore V. Lieffrig , Nicha C. Dvornek , John A. Onofrey

In the realm of medical image segmentation, both CNN-based and Transformer-based models have been extensively explored. However, CNNs exhibit limitations in long-range modeling capabilities, whereas Transformers are hampered by their…

Image and Video Processing · Electrical Eng. & Systems 2024-11-11 Jiacheng Ruan , Jincheng Li , Suncheng Xiang

Accurate reorientation and segmentation of the left ventricular (LV) is essential for the quantitative analysis of myocardial perfusion imaging (MPI), in which one critical step is to reorient the reconstructed transaxial nuclear cardiac…

Image and Video Processing · Electrical Eng. & Systems 2023-10-17 Yangfan Ni , Duo Zhang , Gege Ma , Lijun Lu , Zhongke Huang , Wentao Zhu

In this paper, we present UNet++, a new, more powerful architecture for medical image segmentation. Our architecture is essentially a deeply-supervised encoder-decoder network where the encoder and decoder sub-networks are connected through…

Computer Vision and Pattern Recognition · Computer Science 2018-07-27 Zongwei Zhou , Md Mahfuzur Rahman Siddiquee , Nima Tajbakhsh , Jianming Liang

Automatic tumor or lesion segmentation is a crucial step in medical image analysis for computer-aided diagnosis. Although the existing methods based on Convolutional Neural Networks (CNNs) have achieved the state-of-the-art performance,…

Image and Video Processing · Electrical Eng. & Systems 2022-08-01 Shuchao Pang , Anan Du , Mehmet A. Orgun , Yan Wang , Quan Z. Sheng , Shoujin Wang , Xiaoshui Huang , Zhenmei Yu

Vision Transformers (ViT)s have recently become popular due to their outstanding modeling capabilities, in particular for capturing long-range information, and scalability to dataset and model sizes which has led to state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2022-04-06 Ali Hatamizadeh , Ziyue Xu , Dong Yang , Wenqi Li , Holger Roth , Daguang Xu

The aging population poses numerous challenges to healthcare, including the increase in chronic wounds in the elderly. The current approach to wound assessment by therapists based on photographic documentation is subjective, highlighting…

Computer Vision and Pattern Recognition · Computer Science 2024-09-02 Vanessa Borst , Timo Dittus , Konstantin Müller , Samuel Kounev

As an essential prerequisite for developing a medical intelligent assistant system, medical image segmentation has received extensive research and concentration from the neural network community. A series of UNet-like networks with…

Image and Video Processing · Electrical Eng. & Systems 2022-05-25 Ledan Qian , Xiao Zhou , Yi Li , Zhongyi Hu

While CNN-based methods have been the cornerstone of medical image segmentation due to their promising performance and robustness, they suffer from limitations in capturing long-range dependencies. Transformer-based approaches are currently…

Computer Vision and Pattern Recognition · Computer Science 2023-01-27 Reza Azad , Yiwei Jia , Ehsan Khodapanah Aghdam , Julien Cohen-Adad , Dorit Merhof

Semantic segmentation has a broad range of applications in a variety of domains including land coverage analysis, autonomous driving, and medical image analysis. Convolutional neural networks (CNN) and Vision Transformers (ViTs) provide the…

Computer Vision and Pattern Recognition · Computer Science 2023-05-08 Hans Thisanke , Chamli Deshan , Kavindu Chamith , Sachith Seneviratne , Rajith Vidanaarachchi , Damayanthi Herath

Vision transformers (ViTs) are usually considered to be less light-weight than convolutional neural networks (CNNs) due to the lack of inductive bias. Recent works thus resort to convolutions as a plug-and-play module and embed them in…

Computer Vision and Pattern Recognition · Computer Science 2022-07-13 Tao Huang , Lang Huang , Shan You , Fei Wang , Chen Qian , Chang Xu

Due to low tissue contrast, irregular object appearance, and unpredictable location variation, segmenting the objects from different medical imaging modalities (e.g., CT, MR) is considered as an important yet challenging task. In this…

Computer Vision and Pattern Recognition · Computer Science 2018-05-10 Jinquan Sun , Yinghuan Shi , Yang Gao , Lei Wang , Luping Zhou , Wanqi Yang , Dinggang Shen