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Large Language Models (LLMs) have shown promising performance on diverse medical benchmarks, highlighting their potential in supporting real-world clinical tasks. Retrieval-Augmented Generation (RAG) has emerged as a key approach for…

Computation and Language · Computer Science 2025-09-30 Kaishuai Xu , Wenjun Hou , Yi Cheng , Wenjie Li

Large language models (LLM) hold significant potential for applications in biomedicine, but they struggle with hallucinations and outdated knowledge. While retrieval-augmented generation (RAG) is generally employed to address these issues,…

Computation and Language · Computer Science 2025-09-23 Jiwoong Sohn , Yein Park , Chanwoong Yoon , Sihyeon Park , Hyeon Hwang , Mujeen Sung , Hyunjae Kim , Jaewoo Kang

Large language models (LLMs) often generate outdated or inaccurate information based on static training datasets. Retrieval-augmented generation (RAG) mitigates this by integrating outside data sources. While previous RAG systems used…

Large language models (LLMs) have shown promise in medical question answering but often struggle with hallucinations and shallow reasoning, particularly in tasks requiring nuanced clinical understanding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2025-08-25 Ziyu Wang , Elahe Khatibi , Amir M. Rahmani

Artificial Intelligence (AI) has demonstrated significant potential in healthcare, particularly in disease diagnosis and treatment planning. Recent progress in Medical Large Vision-Language Models (Med-LVLMs) has opened up new possibilities…

Machine Learning · Computer Science 2025-03-04 Peng Xia , Kangyu Zhu , Haoran Li , Tianze Wang , Weijia Shi , Sheng Wang , Linjun Zhang , James Zou , Huaxiu Yao

Large language models equipped with retrieval-augmented generation (RAG) represent a burgeoning field aimed at enhancing answering capabilities by leveraging external knowledge bases. Although the application of RAG with language-only…

Computer Vision and Pattern Recognition · Computer Science 2024-06-03 Cheng Tan , Jingxuan Wei , Linzhuang Sun , Zhangyang Gao , Siyuan Li , Bihui Yu , Ruifeng Guo , Stan Z. Li

Large language models (LLMs) are transforming the landscape of medicine, yet two fundamental challenges persist: keeping up with rapidly evolving medical knowledge and providing verifiable, evidence-grounded reasoning. Retrieval-augmented…

Medical vision-language models (VLMs) achieve strong performance in diagnostic reporting and image-text alignment, yet their underlying reasoning mechanisms remain fundamentally correlational, exhibiting reliance on superficial statistical…

Machine Learning · Computer Science 2026-01-27 Weiqin Yang , Haowen Xue , Qingyi Peng , Hexuan Hu , Qian Huang , Tingbo Zhang

Medical question-answering (QA) systems can benefit from advances in large language models (LLMs), but directly applying LLMs to the clinical domain poses challenges such as maintaining factual accuracy and avoiding hallucinations. In this…

Computation and Language · Computer Science 2025-12-08 Tasnimul Hassan , Md Faisal Karim , Haziq Jeelani , Elham Behnam , Robert Green , Fayeq Jeelani Syed

Incentivizing the reasoning ability of Multimodal Large Language Models (MLLMs) is essential for medical applications to transparently analyze medical scans and provide reliable diagnosis. However, existing medical MLLMs rely solely on…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Lehan Wang , Yi Qin , Honglong Yang , Xiaomeng Li

Large Language Models (LLMs) have shown remarkable reasoning capabilities, while their practical applications are limited by severe factual hallucinations due to limitations in the timeliness, accuracy, and comprehensiveness of their…

Artificial Intelligence · Computer Science 2025-06-10 Xinyan Guan , Jiali Zeng , Fandong Meng , Chunlei Xin , Yaojie Lu , Hongyu Lin , Xianpei Han , Le Sun , Jie Zhou

The Retrieval-Augmented Language Model (RALM) has shown remarkable performance on knowledge-intensive tasks by incorporating external knowledge during inference, which mitigates the factual hallucinations inherited in large language models…

Computation and Language · Computer Science 2024-12-20 Yuan Xia , Jingbo Zhou , Zhenhui Shi , Jun Chen , Haifeng Huang

Large language models (LLMs) have demonstrated strong capabilities in medical question answering; however, purely parametric models often suffer from knowledge gaps and limited factual grounding. Retrieval-augmented generation (RAG)…

Computation and Language · Computer Science 2026-04-09 Nusrat Sultana , Abdullah Muhammad Moosa , Kazi Afzalur Rahman , Sajal Chandra Banik

Large reasoning models such as DeepSeek-R1 and OpenAI o1 generate extended chains of thought spanning thousands of tokens, yet their integration with retrieval-augmented generation (RAG) remains fundamentally misaligned. Current RAG systems…

Information Retrieval · Computer Science 2026-04-30 Dongxin Guo , Jikun Wu , Siu Ming Yiu

Retrieval-augmented generation (RAG) has proven to be effective in mitigating hallucinations in large language models, yet its effectiveness remains limited in complex, multi-step reasoning scenarios. Recent efforts have incorporated…

Computation and Language · Computer Science 2025-12-29 Wenda Wei , Yu-An Liu , Ruqing Zhang , Jiafeng Guo , Lixin Su , Shuaiqiang Wang , Dawei Yin , Maarten de Rijke , Xueqi Cheng

Retrieval-augmented generation (RAG) has emerged as a promising approach to enhance the performance of large language models (LLMs) in knowledge-intensive tasks such as those from medical domain. However, the sensitive nature of the medical…

Computation and Language · Computer Science 2024-11-15 Nghia Trung Ngo , Chien Van Nguyen , Franck Dernoncourt , Thien Huu Nguyen

Retrieval-Augmented Generation (RAG) has been shown to enhance the factual accuracy of Large Language Models (LLMs), but existing methods often suffer from limited reasoning capabilities in effectively using the retrieved evidence,…

Computation and Language · Computer Science 2024-10-03 Shayekh Bin Islam , Md Asib Rahman , K S M Tozammel Hossain , Enamul Hoque , Shafiq Joty , Md Rizwan Parvez

Retrieval-Augmented Generation (RAG) effectively enhances Large Language Models (LLMs) by incorporating retrieved external knowledge into the generation process. Reasoning models improve LLM performance in multi-hop QA tasks, which require…

Computation and Language · Computer Science 2026-01-21 Guo Chen , Junjie Huang , Huaijin Xie , Fei Sun , Tao Jia

Despite the potential of Large Language Models (LLMs) in medicine, they may generate responses lacking supporting evidence or based on hallucinated evidence. While Retrieval Augment Generation (RAG) is popular to address this issue, few…

Large Language Models (LLMs) have catalyzed significant advancements in Natural Language Processing (NLP), yet they encounter challenges such as hallucination and the need for domain-specific knowledge. To mitigate these, recent…

Computation and Language · Computer Science 2025-07-01 Yucheng Hu , Yuxing Lu
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