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Deep learning models in computational pathology often fail to generalize across cohorts and institutions due to domain shift. Existing approaches either fail to leverage unlabeled data from the target domain or rely on image-to-image…

Computer Vision and Pattern Recognition · Computer Science 2026-01-27 Tengyue Zhang , Ruiwen Ding , Luoting Zhuang , Yuxiao Wu , Erika F. Rodriguez , William Hsu

Both medical care and observational studies in oncology require a thorough understanding of a patient's disease progression and treatment history, often elaborately documented in clinical notes. Despite their vital role, no current oncology…

Computation and Language · Computer Science 2024-03-18 Madhumita Sushil , Vanessa E. Kennedy , Divneet Mandair , Brenda Y. Miao , Travis Zack , Atul J. Butte

Explainability is key to enhancing artificial intelligence's trustworthiness in medicine. However, several issues remain concerning the actual benefit of explainable models for clinical decision-making. Firstly, there is a lack of consensus…

Image and Video Processing · Electrical Eng. & Systems 2023-12-18 Kazuma Kobayashi , Yasuyuki Takamizawa , Mototaka Miyake , Sono Ito , Lin Gu , Tatsuya Nakatsuka , Yu Akagi , Tatsuya Harada , Yukihide Kanemitsu , Ryuji Hamamoto

The LIDC-IDRI database is the most popular benchmark for lung cancer prediction. However, with subjective assessment from radiologists, nodules in LIDC may have entirely different malignancy annotations from the pathological ground truth,…

Image and Video Processing · Electrical Eng. & Systems 2022-07-29 Hanxiao Zhang , Xiao Gu , Minghui Zhang , Weihao Yu , Liang Chen , Zhexin Wang , Feng Yao , Yun Gu , Guang-Zhong Yang

The scarcity of annotated surgical data poses a significant challenge for developing deep learning systems in computer-assisted interventions. While diffusion models can synthesize realistic images, they often suffer from data memorization,…

Computer Vision and Pattern Recognition · Computer Science 2025-09-24 Danush Kumar Venkatesh , Stefanie Speidel

Data scarcity in medical imaging poses significant challenges due to privacy concerns. Diffusion models, a recent generative modeling technique, offer a potential solution by generating synthetic and realistic data. However, questions…

Image and Video Processing · Electrical Eng. & Systems 2024-12-24 Abdullah al Nomaan Nafi , Md. Alamgir Hossain , Rakib Hossain Rifat , Md Mahabub Uz Zaman , Md Manjurul Ahsan , Shivakumar Raman

Early detection of lung cancer in chest radiographs (CXRs) is crucial for improving patient outcomes, yet nodule detection remains challenging due to their subtle appearance and variability in radiological characteristics like size,…

Computer Vision and Pattern Recognition · Computer Science 2026-03-03 Aryan Goyal , Shreshtha Singh , Ashish Mittal , Manoj Tadepalli , Piyush Kumar , Preetham Putha

Machine learning models have shown increased accuracy in classification tasks when the training process incorporates human perceptual information. However, a challenge in training human-guided models is the cost associated with collecting…

Computer Vision and Pattern Recognition · Computer Science 2023-11-10 Colton R. Crum , Aidan Boyd , Kevin Bowyer , Adam Czajka

The annotated medical images are usually expensive to be collected. This paper proposes a deep learning method on small data to classify Common Imaging Signs of Lung diseases (CISL) in computed tomography (CT) images. We explore both the…

Computer Vision and Pattern Recognition · Computer Science 2019-03-04 Guocai He

One of the challenges of using machine learning techniques with medical data is the frequent dearth of source image data on which to train. A representative example is automated lung cancer diagnosis, where nodule images need to be…

Computer Vision and Pattern Recognition · Computer Science 2019-09-10 Steve Kommrusch , Louis-Noël Pouchet

Augmentation by generative modelling yields a promising alternative to the accumulation of surgical data, where ethical, organisational and regulatory aspects must be considered. Yet, the joint synthesis of (image, mask) pairs for…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Yannik Frisch , Christina Bornberg , Moritz Fuchs , Anirban Mukhopadhyay

Imaging has occupied a huge role in the management of patients, whether hospitalized or not. Depending on the patients clinical problem, a variety of imaging modalities were available for use. This gave birth of the annotation of medical…

Computer Vision and Pattern Recognition · Computer Science 2013-07-04 Mouhamed Gaith Ayadi , Riadh Bouslimi , Jalel Akaichi

Deep neural networks for medical image diagnosis often achieve high predictive accuracy while relying on spurious or clinically irrelevant visual cues, limiting their trustworthiness in practice. Post-hoc explanation methods are widely used…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Zubair Faruqui , Rahul Dubey

From the simple measurement of tissue attributes in pathology workflow to designing an explainable diagnostic/prognostic AI tool, access to accurate semantic segmentation of tissue regions in histology images is a prerequisite. However,…

Image and Video Processing · Electrical Eng. & Systems 2021-08-31 Mostafa Jahanifar , Neda Zamani Tajeddin , Navid Alemi Koohbanani , Nasir Rajpoot

Convolutional Neural Network (CNN)-based accurate prediction typically requires large-scale annotated training data. In Medical Imaging, however, both obtaining medical data and annotating them by expert physicians are challenging; to…

Computer Vision and Pattern Recognition · Computer Science 2019-05-30 Changhee Han , Kohei Murao , Shin'ichi Satoh , Hideki Nakayama

Training supervised deep neural networks that perform defect detection and segmentation requires large-scale fully-annotated datasets, which can be hard or even impossible to obtain in industrial environments. Generative AI offers…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Gabriele Valvano , Antonino Agostino , Giovanni De Magistris , Antonino Graziano , Giacomo Veneri

Supervised deep learning methods for segmentation require large amounts of labelled training data, without which they are prone to overfitting, not generalizing well to unseen images. In practice, obtaining a large number of annotations…

Computer Vision and Pattern Recognition · Computer Science 2019-03-01 Krishna Chaitanya , Neerav Karani , Christian Baumgartner , Olivio Donati , Anton Becker , Ender Konukoglu

Artificial intelligence (AI) continues to transform data analysis in many domains. Progress in each domain is driven by a growing body of annotated data, increased computational resources, and technological innovations. In medicine, the…

Computer Vision and Pattern Recognition · Computer Science 2023-08-09 Ahmad Chaddad , Qizong lu , Jiali Li , Yousef Katib , Reem Kateb , Camel Tanougast , Ahmed Bouridane , Ahmed Abdulkadir

Public imaging datasets are critical for the development and evaluation of automated tools in cancer imaging. Unfortunately, many do not include annotations or image-derived features, complicating their downstream analysis. Artificial…

Computer Vision and Pattern Recognition · Computer Science 2023-06-02 Deepa Krishnaswamy , Dennis Bontempi , Vamsi Thiriveedhi , Davide Punzo , David Clunie , Christopher P Bridge , Hugo JWL Aerts , Ron Kikinis , Andrey Fedorov

Medical imaging diagnosis increasingly relies on Machine Learning (ML) models. This is a task that is often hampered by severely imbalanced datasets, where positive cases can be quite rare. Their use is further compromised by their limited…

Machine Learning · Computer Science 2024-01-26 Yumnah Hasan , Allan de Lima , Fatemeh Amerehi , Darian Reyes Fernandez de Bulnes , Patrick Healy , Conor Ryan