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Phylogenetic Diversity (PD) is a measure of the overall biodiversity of a set of present-day species (taxa) within a phylogenetic tree. In Maximize Phylogenetic Diversity (MPD) one is asked to find a set of taxa (of bounded size/cost) for…

Computational Complexity · Computer Science 2024-03-22 Mark Jones , Jannik Schestag

Although adversarial examples and model robustness have been extensively studied in the context of linear models and neural networks, research on this issue in tree-based models and how to make tree-based models robust against adversarial…

Machine Learning · Computer Science 2019-06-12 Hongge Chen , Huan Zhang , Duane Boning , Cho-Jui Hsieh

We propose a new hybrid quantum algorithm based on the classical Ant Colony Optimization algorithm to produce approximate solutions for NP-hard problems, in particular optimization problems. First, we discuss some previously proposed…

Quantum Physics · Physics 2022-06-30 Mikel Garcia de Andoin , Javier Echanobe

Motivation: The abundance of gene flow in the Tree of Life challenges the notion that evolution can be represented with a fully bifurcating process, as this process cannot capture important biological realities like hybridization,…

Populations and Evolution · Quantitative Biology 2023-11-10 Zhaoxing Wu , Claudia Solis-Lemus

Early literature on genome rearrangement modelling views the problem of computing evolutionary distances as an inherently combinatorial one. In particular, attention was given to estimating distances using the minimum number of events…

Populations and Evolution · Quantitative Biology 2023-01-12 Joshua Stevenson , Venta Terauds , Jeremy Sumner

In evolutionary biology, genetic sequences carry with them a trace of the underlying tree that describes their evolution from a common ancestral sequence. The question of how many sequence sites are required to recover this evolutionary…

Populations and Evolution · Quantitative Biology 2008-06-17 Mareike Fischer , Mike Steel

The emergence of huge-scale, data-intensive linear optimization (LO) problems in applications such as machine learning has driven the need for more computationally efficient interior point methods (IPMs). While conventional IPMs are…

We present an axiomatic framework for analyzing the algorithmic properties of decision trees. This framework supports the classification of decision tree problems through structural and ancestral constraints within a rigorous mathematical…

Machine Learning · Computer Science 2025-10-24 Xi He , Max A. Little

We propose a novel method for automatic program synthesis. P-Tree Programming represents the program search space through a single probabilistic prototype tree. From this prototype tree we form program instances which we evaluate on a given…

Artificial Intelligence · Computer Science 2017-07-13 Christian Oesch

Many biological studies involve inferring the evolutionary history of a sample of individuals from a large population and interpreting the reconstructed tree. Such an ascertained tree typically represents only a small part of a…

Populations and Evolution · Quantitative Biology 2024-08-13 Michael Celentano , William S. DeWitt , Sebastian Prillo , Yun S. Song

Genetic programming (GP) is an evolutionary computation technique to solve problems in an automated, domain-independent way. Rather than identifying the optimum of a function as in more traditional evolutionary optimization, the aim of GP…

Neural and Evolutionary Computing · Computer Science 2019-05-15 Andrei Lissovoi , Pietro S. Oliveto

Optimizing the mRNA codon has an essential impact on gene expression for a specific target protein. It is an NP-hard problem; thus, exact solutions to such optimization problems become computationally intractable for realistic problem sizes…

Quantum Physics · Physics 2024-05-13 Hongfeng Zhang , Aritra Sarkar , Koen Bertels

In recent years, the researches about solving partial differential equations (PDEs) based on artificial neural network have attracted considerable attention. In these researches, the neural network models are usually designed depend on…

Neural and Evolutionary Computing · Computer Science 2024-05-21 Bo Zhang , Chao Yang

A frame is a generalization of a basis of a vector space to a redundant overspanning set whose vectors are linearly dependent. Frames find applications in signal processing and quantum information theory. We present a genetic algorithm that…

Computational Physics · Physics 2025-08-13 Sebastián Roca-Jerat , Juan Román-Roche

Simulating noninteracting fermion systems is a common task in computational many-body physics. In absence of translational symmetries, modeling free fermions on $N$ modes usually requires poly$(N)$ computational resources. While often…

Quantum Physics · Physics 2026-02-24 Maarten Stroeks , Daan Lenterman , Barbara Terhal , Yaroslav Herasymenko

The Dollo model for reconstructing evolutionary trees from binary characters has been proposed as a generalization of the infinite sites model, also known as the Perfect Phylogeny. In particular, the Dollo model is considered more realistic…

Data Structures and Algorithms · Computer Science 2025-06-17 Paola Bonizzoni , Gianluca Della Vedova , Mauricio Soto Gomez , Gabriella Trucco

Among the genetic algorithms generally used for optimization problems in the recent decades, quantum-inspired variants are known for fast and high-fitness convergence and small resource requirement. Here the application to the patient…

Neural and Evolutionary Computing · Computer Science 2025-06-06 Akira SaiToh , Arezoo Modiri , Amit Sawant , Robabeh Rahimi

Distance-based phylogenetic algorithms attempt to solve the NP-hard least squares phylogeny problem by mapping an arbitrary dissimilarity map representing biological data to a tree metric. The set of all dissimilarity maps is a Euclidean…

Populations and Evolution · Quantitative Biology 2013-07-24 Ruth Davidson , Seth Sullivant

One of the challenges of quantum computers in the near- and mid- term is the limited number of qubits we can use for computations. Finding methods that achieve useful quantum improvements under size limitations is thus a key question in the…

Quantum Physics · Physics 2023-03-29 Mathys Rennela , Sebastiaan Brand , Alfons Laarman , Vedran Dunjko

As researchers collect increasingly large molecular data sets to reconstruct the Tree of Life, the heterogeneity of signals in the genomes of diverse organisms poses challenges for traditional phylogenetic analysis. A class of phylogenetic…

Populations and Evolution · Quantitative Biology 2015-09-11 Liang Liu , Zhenxiang Xi , Shaoyuan Wu , Charles Davis , Scott V. Edwards