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We define some of the programming and system-level challenges facing the application of quantum processing to high-performance computing. Alongside barriers to physical integration, prominent differences in the execution of quantum and…

Quantum Physics · Physics 2017-12-06 Keith A. Britt , Fahd A. Mohiyaddin , Travis S. Humble

Large language models (LLMs) excel at general programming but struggle with domain-specific software development, necessitating domain specialization methods for LLMs to learn and utilize domain knowledge and data. However, existing…

Software Engineering · Computer Science 2026-04-28 Xue Jiang , Ge Li , Jiaru Qian , Xianjie Shi , Chenjie Li , Hao Zhu , Ziyu Wang , Jielun Zhang , Zheyu Zhao , Lingwei Wu , Kechi Zhang , Jia Li , Wenpin Jiao , Zhi Jin , Yihong Dong

The Matrix Element Method has proven to be a powerful method to optimally exploit the information available in detector data. Its widespread use is nevertheless impeded by its complexity and the associated computing time. MoMEMta, a C++…

We present a multi-agent system for automation of scientific research tasks, cmbagent (https://github.com/CMBAgents/cmbagent). The system is formed by about 30 Large Language Model (LLM) agents and implements a Planning & Control strategy…

Recent advancements in natural language processing (NLP) have enabled the development of automated tools that support various domains, including software engineering. However, while NLP and artificial intelligence (AI) research has…

Software Engineering · Computer Science 2025-08-25 Sonia Nicoletti , Paolo Ciancarini

Deep generative models have recently shown success in solving complex engineering design problems where models predict solutions that address the design requirements specified as input. However, there remains a challenge in aligning such…

Machine Learning · Computer Science 2025-02-06 Hyunmin Cheong , Mohammadmehdi Ataei , Amir Hosein Khasahmadi , Pradeep Kumar Jayaraman

Computer models are widely used across a range of scientific disciplines to describe various complex physical systems, however to perform full uncertainty quantification we often need to employ emulators. An emulator is a fast statistical…

Methodology · Statistics 2022-10-20 Ian Vernon , Jonathan Owen , Jonathan Carter

The growing complexity and sophistication of the organizational information systems, and hospital ones particularly, render difficult their comprehension and, consequently, the implementation of control mechanisms that may assure, at all…

Software Engineering · Computer Science 2012-04-11 Carlos Santos , Armindo Rebelo , Carla Ferreira , José Tribolet

In an era where scientific experimentation is often costly, multi-fidelity emulation provides a powerful tool for predictive scientific computing. While there has been notable work on multi-fidelity modeling, existing models do not…

Molecular dynamics (MD) simulation is a powerful tool for studying biomolecular structural changes, molecular recognition, transmembrane transport, and functional mechanisms. However, its practical bottleneck lies not only in software…

Quantitative Methods · Quantitative Biology 2026-04-22 Zhenyu Ma , Chunyi Yang , Yuyang Song , Jingyi Zhu , Letian Yang , Limei Xu , Min Xiao , Xukai Jiang

Recent advancements in large language models (LLMs) have led to the creation of intelligent agents capable of performing complex tasks. This paper introduces a novel LLM-based multimodal agent framework designed to operate smartphone…

Computer Vision and Pattern Recognition · Computer Science 2023-12-25 Chi Zhang , Zhao Yang , Jiaxuan Liu , Yucheng Han , Xin Chen , Zebiao Huang , Bin Fu , Gang Yu

Within academia and industry, there has been a need for expansive simulation frameworks that include model-based simulation of sensors, mobile vehicles, and the environment around them. To this end, the modular, real-time, and open-source…

The emergence of Big Data in recent years has resulted in a growing need for efficient data processing solutions. While infrastructures with sufficient compute power are available, the I/O bottleneck remains. The Linux page cache is an…

Distributed, Parallel, and Cluster Computing · Computer Science 2021-01-06 Hoang-Dung Do , Valerie Hayot-Sasson , Rafael Ferreira da Silva , Christopher Steele , Henri Casanova , Tristan Glatard

Numerical simulation is one of the mainstream methods in scientific research, typically performed by professional engineers. With the advancement of multi-agent technology, using collaborating agents to replicate human behavior shows…

Multiagent Systems · Computer Science 2026-01-13 Chunwei Yang , Yankai Wang , Jianxiang Tang , Haojie Qu , Ziqiang Zou , YuLiu , Chunrui Deng , Zhifang Qiu , Ming Ding

Agent-based models (ABMs) and video games, including those taking advantage of virtual reality (VR), have undergone a remarkable parallel evolution, achieving impressive levels of complexity and sophistication. This paper argues that while…

Simulating high quality user behavior data has always been a fundamental problem in human-centered applications, where the major difficulty originates from the intricate mechanism of human decision process. Recently, substantial evidences…

Information Retrieval · Computer Science 2024-02-16 Lei Wang , Jingsen Zhang , Hao Yang , Zhiyuan Chen , Jiakai Tang , Zeyu Zhang , Xu Chen , Yankai Lin , Ruihua Song , Wayne Xin Zhao , Jun Xu , Zhicheng Dou , Jun Wang , Ji-Rong Wen

We introduce COMBO - a fully neural NLP system for accurate part-of-speech tagging, morphological analysis, lemmatisation, and (enhanced) dependency parsing. It predicts categorical morphosyntactic features whilst also exposes their vector…

Computation and Language · Computer Science 2021-09-14 Mateusz Klimaszewski , Alina Wróblewska

Large Language Models (LLMs) have shown impressive potential to simulate human behavior. We identify a fundamental challenge in using them to simulate experiments: when LLM-simulated subjects are blind to the experimental design (as is…

Artificial Intelligence · Computer Science 2025-11-25 George Gui , Olivier Toubia

Agentic systems, in which diverse agents cooperate to tackle challenging problems, are exploding in popularity in the AI community. However, existing agentic frameworks take a relatively narrow view of agents, apply a centralized model, and…

Multiagent Systems · Computer Science 2026-01-30 Alok Kamatar , J. Gregory Pauloski , Yadu Babuji , Ryan Chard , Mansi Sakarvadia , Daniel Babnigg , Kyle Chard , Ian Foster

Modern machine learning accelerators are designed to efficiently execute deep neural networks (DNNs) by optimizing data movement, memory hierarchy, and compute throughput. However, emerging DNN models such as large language models, state…

Hardware Architecture · Computer Science 2025-09-03 Shubham Negi , Manik Singhal , Aayush Ankit , Sudeep Bhoja , Kaushik Roy
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